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Journal Articles

A Phase I/Pilot Study of CPX-351 [Daunorubicin and Cytarabine Liposome for Injection (Vyxeos®)] for Children, Adolescents and Young Adults with Recurrent or Refractory Acute Leukemia

Michael J. Absalon, MD PhD, Erin H. Breese, MD PhD, Lynn Lee, MD, Maureen M O'Brien, MD MS, Christine L Phillips, MD, Karen Burns, MD, Benjamin Mizukawa, MD, Qi An, Jennifer Mangino, MD, Joel Kaplan, DO, Robin Norris, MD, John Peter Perentesis, MD

Blood (2018) 132 (Supplement 1): 336.

https://doi.org/10.1182/blood-2018-99-119618

Published: 2018

Journal Articles

Proton Sensor GPR68 Is Essential to Maintain Myeloid Malignancies

Xiaofei He, B.S., Mark Wunderlich, MS, Benjamin Mizukawa, MD, James C. Mulloy, PhD, Saran Feng, MD, PhD, Lauren Lawley, B.S., Caleb Hawkins, B.S., Wenxin Fan, B.S., Guokun Zhou, PhD, Xiang-ming Zha, PhD, Jiajia Zhang, PhD, Johnie Hodge, MD,PhD, Daping Fan, PhD, Stephanie Halene, MD, Jing Fang, MD PhD

Blood (2018) 132 (Supplement 1): 1353.

https://doi.org/10.1182/blood-2018-99-110399

Published: 2018

Journal Articles

In Vitro Approach for the Identification of Exceptional Responders in Acute Myeloid Leukemia

Eric O'Brien, BSc, Brett VanCauwenbergh, BSc, Luke Byerly, BSc, Alexander Merk, BSc, Mayur Sarangdhar, PhD, Mark Wunderlich, MS, Mitali Basu, MSc, Benjamin Mizukawa, MD, Erin H. Breese, MD PhD, William Seibel, PhD, John Peter Perentesis, MD

Blood (2018) 132 (Supplement 1): 2212.

https://doi.org/10.1182/blood-2018-99-116650

Published: 2018

Journal Articles

PD-1 Inhibition Enhances Blinatumomab Response in a UCB/PDX Model of B-Cell Acute Lymphoblastic Leukemia

Mark Wunderlich, MS, Nicole Manning, Christina Sexton, Perentesis P John, MD, Benjamin Mizukawa, MD, James C. Mulloy, PhD

Blood (2017) 130 (Supplement 1): 1318.

https://doi.org/10.1182/blood.V130.Suppl_1.1318.1318

Published: 2017

Journal Articles

Exceptional Responses to Epigenetic Based Therapy in Pediatric and Young Adult Monosomy 7 MDS/AML Patients with and without TP53 Mutations

LaQuita M Jones, DO, Maureen M O'Brien, MD, Erin H. Breese, MD PhD, Karen Burns, MD, Jennifer Mangino, MD, Michael J. Absalon, MD PhD, Javier A. El-Bietar, MD, Michael Grimley, MD, Benjamin Mizukawa, MD, Lynn Lee, MD, John Peter Perentesis, MD, Christine L Phillips, MD

Blood (2017) 130 (Supplement 1): 3895.

https://doi.org/10.1182/blood.V130.Suppl_1.3895.3895

Published: 2017

Journal Articles

Protease-Activated Receptor 1 (PAR-1) Inhibits Proliferation but Enhances Leukemia Stem Cell Activity in Acute Myeloid Leukemia

Susumu Goyama, MD PhD, Mahesh Shrestha, Janet Schibler, Leah Rosenfeldt, Whitney Miller, Eric O'Brien, Benjamin Mizukawa, MD, Toshio Kitamura, MD PhD, Joseph S. Palumbo, MD, James C. Mulloy, PhD

Blood (2016) 128 (22): 2730.

https://doi.org/10.1182/blood.V128.22.2730.2730

Published: 2016

Journal Articles

A Xenograft Model of Lymphocyte-Independent, Effector-Driven Macrophage Activation SyndRome Amenable to Anti-CD33 and Anti-IL-6R Treatment

Mark Wunderlich, MS, Courtney Stockman, Mahima Devarajan, Navin Ravishankar, Christina Sexton, Ashish R Kumar, MBBS, PhD, Benjamin Mizukawa, MD, James C. Mulloy, PhD

Blood (2016) 128 (22): 3684.

https://doi.org/10.1182/blood.V128.22.3684.3684

Published: 2016

Journal Articles

Maintenance Of Bone Marrow Residency and Self-Renewal Of Leukemic Stem Cells By Cdc42 Gtpase

Benjamin Mizukawa, MD, Eric O'Brien, BS, Wei Liu, MD, PhD, Daniel Moriera Ridsdale, MD, Mark Wunderlich, MS, Yi Zheng, PhD, James C. Mulloy, PhD

Blood (2013) 122 (21): 2889.

https://doi.org/10.1182/blood.V122.21.2889.2889

Published: 2013

Journal Articles

NSGS Mice Develop a Progressive, Myeloid Cell Dependent Aplastic Anemia and Bone Marrow Failure Upon Engraftment With Human Umbilical Cord Blood CD34+ Cells

Mark Wunderlich, MS, Christina Sexton, Benjamin Mizukawa, MD, James C. Mulloy, PhD

Blood (2013) 122 (21): 3716.

https://doi.org/10.1182/blood.V122.21.3716.3716

Published: 2013

Journal Articles

Leukemic and Hematopoietic Stem Cells Compete for the Same Functional Marrow Niche in a MLL-AF9 Murine Leukemia Model

Ronan G. Desmond, MD, MRCP, FRCPath, Taha Bat, Olena Kamenyeva, Benjamin Mizukawa, MD, James C. Mulloy, PhD, Andre Larochelle, MD, PhD, Cynthia E. Dunbar, MD

Blood (2012) 120 (21): 4897.

https://doi.org/10.1182/blood.V120.21.4897.4897

Published: 2012

Journal Articles

Rac GTPase Survival Signaling Through Anti-Apoptotic Bcl-2 Proteins Reveals a Target for Combination Therapy in MLL-AF9 Acute Myeloid Leukemia

Benjamin Mizukawa, MD, Mahesh Shrestha, MS, Mark Wunderlich, MS, Fu-Sheng Chou, MD, PhD, Andrea Griesinger, BS, Ashish Kumar, MBBS, PhD, Yi Zheng, PhD, David A. Williams, MD, James C. Mulloy, PhD

Blood (2011) 118 (21): 1536.

https://doi.org/10.1182/blood.V118.21.1536.1536

Published: 2011

Journal Articles

A Novel Method of Mobilizing Leukemia Initiating Cells by a Small Molecule Cdc42 Activity-Specific Inhibitor (CASIN) for Acute Myeloid Leukemia Therapy.

Wei Liu, MD, MS, Benjamin Mizukawa, MD, Mark Wunderlich, MS, James F Johnson, James C. Mulloy, PhD, Yi Zheng, PhD

Blood (2009) 114 (22): 13.

https://doi.org/10.1182/blood.V114.22.13.13

Published: 2009

Journal Articles

Bcl-XL Is a Critical Mediator of Rac Signaling in MLL-AF9-Induced Acute Myeloid Leukemia.

Benjamin Mizukawa, MD, Junping Wei, MD, PhD, Mark Wunderlich, MS, Fu-Sheng Chou, MD, Yi Zheng, PhD, David A. Williams, MD, James C. Mulloy, PhD

Blood (2009) 114 (22): 1971.

https://doi.org/10.1182/blood.V114.22.1971.1971

Published: 2009

Journal Articles

A New Immunodeficient Mouse Strain, NOD/SCID IL2Rγ−/− SGM3, Promotes Enhanced Human Hematopoietic Cell Xenografts with a Robust T Cell Component.

Mark Wunderlich, MS, Fu-Sheng Chou, MD, Benjamin Mizukawa, MD, Kevin A Link, PhD, James C. Mulloy, PhD

Blood (2009) 114 (22): 3524.

https://doi.org/10.1182/blood.V114.22.3524.3524

Published: 2009

NARROW

A Phase I/Pilot Study of CPX-351 [Daunorubicin and Cytarabine Liposome for Injection (Vyxeos®)] for Children, Adolescents and Young Adults with Recurrent or Refractory Acute Leukemia

Proton Sensor GPR68 Is Essential to Maintain Myeloid Malignancies

In Vitro Approach for the Identification of Exceptional Responders in Acute Myeloid Leukemia

PD-1 Inhibition Enhances Blinatumomab Response in a UCB/PDX Model of B-Cell Acute Lymphoblastic Leukemia

Exceptional Responses to Epigenetic Based Therapy in Pediatric and Young Adult Monosomy 7 MDS/AML Patients with and without TP53 Mutations

Protease-Activated Receptor 1 (PAR-1) Inhibits Proliferation but Enhances Leukemia Stem Cell Activity in Acute Myeloid Leukemia

A Xenograft Model of Lymphocyte-Independent, Effector-Driven Macrophage Activation SyndRome Amenable to Anti-CD33 and Anti-IL-6R Treatment

Maintenance Of Bone Marrow Residency and Self-Renewal Of Leukemic Stem Cells By Cdc42 Gtpase

NSGS Mice Develop a Progressive, Myeloid Cell Dependent Aplastic Anemia and Bone Marrow Failure Upon Engraftment With Human Umbilical Cord Blood CD34+ Cells

Leukemic and Hematopoietic Stem Cells Compete for the Same Functional Marrow Niche in a MLL-AF9 Murine Leukemia Model

Rac GTPase Survival Signaling Through Anti-Apoptotic Bcl-2 Proteins Reveals a Target for Combination Therapy in MLL-AF9 Acute Myeloid Leukemia

A Novel Method of Mobilizing Leukemia Initiating Cells by a Small Molecule Cdc42 Activity-Specific Inhibitor (CASIN) for Acute Myeloid Leukemia Therapy.

Bcl-XL Is a Critical Mediator of Rac Signaling in MLL-AF9-Induced Acute Myeloid Leukemia.

A New Immunodeficient Mouse Strain, NOD/SCID IL2Rγ−/− SGM3, Promotes Enhanced Human Hematopoietic Cell Xenografts with a Robust T Cell Component.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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