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Journal Articles

AO-176, a Differentiated Clinical-Stage Anti-CD47 Antibody, Demonstrates Potent Anti-Tumor Activity across Multiple Preclinical Models of B Cell Neoplasms

William Casey Wilson, John O Richards, Gabriela Andrejeva, Benjamin J Capoccia, Robyn J Puro, Mike J Donio, Ronald R Hiebsch, Arun K Kashyap, Daniel S Pereira

Blood (2021) 138 (Supplement 1): 2277.

https://doi.org/10.1182/blood-2021-152896

Published: 2021

Journal Articles

Pre-Clinical Combination of AO-176, a Highly Differentiated Clinical Stage CD47 Antibody, with Either Azacitidine or Venetoclax Significantly Enhances DAMP Induction and Phagocytosis of Acute Myeloid Leukemia

Mike J Donio, W. Casey Wilson, PhD, Isra Darwech, Gabriela Andrejeva, PhD, Benjamin J Capoccia, PhD, Robyn J Puro, PhD, Arun K Kashyap, PhD, Daniel S Pereira, PhD

Blood (2020) 136 (Supplement 1): 9–10.

https://doi.org/10.1182/blood-2020-140528

Published: 2020

Journal Articles

Dual-Function Anti-CD47mAbs Induce Tumor Cell Death and Promote Phagocytosis Resulting in Enhanced in Vivo Efficacy

Pamela T. Manning, PhD, Benjamin J. Capoccia, PhD, Michael P. Rettig, PhD, Ronald R. Hiebsch, BS, Robert W. Karr, MD, John F. DiPersio, MD PhD, William A. Frazier, PhD

Blood (2014) 124 (21): 991.

https://doi.org/10.1182/blood.V124.21.991.991

Published: 2014

Journal Articles

Revascularization of ischemic limbs after transplantation of human bone marrow cells with high aldehyde dehydrogenase activity

Benjamin J. Capoccia, Debra L. Robson, Krysta D. Levac, Dustin J. Maxwell, Sarah A. Hohm, Marian J. Neelamkavil, Gillian I. Bell, Anargyros Xenocostas, Daniel C. Link, David Piwnica-Worms, Jan A. Nolta, David A. Hess

Blood (2009) 113 (21): 5340–5351.

https://doi.org/10.1182/blood-2008-04-154567

Published: 2009

Includes: Supplemental data

Journal Articles

Conditioning of Monocytes in the Bone Marrow by Inflammatory Cytokines Inhibits Their Angiogenic Potential at Peripheral Sites of Ischemia

Alyssa D. Gregory, Benjamin J. Capoccia, PhD, Daniel C. Link, MD

Blood (2008) 112 (11): 471.

https://doi.org/10.1182/blood.V112.11.471.471

Published: 2008

Journal Articles

The Inflammatory Subset of Monocytes Stimulates Angiogenesis at Sites of Ischemia by Altering the Balance of Pro- and Anti-Inflammatory Cytokines.

Alyssa D. Gregory, Benjamin J. Capoccia, Daniel C. Link, MD

Blood (2007) 110 (11): 240.

https://doi.org/10.1182/blood.V110.11.240.240

Published: 2007

Journal Articles

Aldehyde Dehydrogenase-Activity Purifies Multiple Hemangiogenic Lineages That Accelerate Vascularization of Ischemic Tissue through Paracrine Support of Neovessel Formation.

Krysta D. Levac, PhD, Debra L. Robson, BSC, Marian J. Neelamkavil, BSc, Sarah A. Hohm, BSc, Benjamin J. Capoccia, BSc, Daniel C. Link, MD, Jan A. Nolta, PhD, David A. Hess, PhD

Blood (2007) 110 (11): 3716.

https://doi.org/10.1182/blood.V110.11.3716.3716

Published: 2007

Journal Articles

Angiogenic cells can be rapidly mobilized and efficiently harvested from the blood following treatment with AMD3100

Rebecca M. Shepherd, Benjamin J. Capoccia, Steven M. Devine, John DiPersio, Kathryn M. Trinkaus, David Ingram, Daniel C. Link

Blood (2006) 108 (12): 3662–3667.

https://doi.org/10.1182/blood-2006-06-030577

Published: 2006

Journal Articles

The Differential Role of Stromal Derived Factor-1 (SDF-1) and Monocyte Chemoattractant Protein-1 (MCP-1) in the Recruitment of Angiogenic Cells to Ischemic Tissue.

Benjamin J. Capoccia, Daniel C. Link, M.D

Blood (2006) 108 (11): 417.

https://doi.org/10.1182/blood.V108.11.417.417

Published: 2006

Journal Articles

G-CSF and AMD3100 mobilize monocytes into the blood that stimulate angiogenesis in vivo through a paracrine mechanism

Benjamin J. Capoccia, Rebecca M. Shepherd, Daniel C. Link

Blood (2006) 108 (7): 2438–2445.

https://doi.org/10.1182/blood-2006-04-013755

Published: 2006

Journal Articles

Bone Marrow-Derived Aldehyde Dehdrogenase Expressing Cells Possess Endothelial Progenitor Function in Addition to Hematopoietic Repopulating Ability and Aid in Blood Flow Recovery after Acute Ischemic Injury.

Benjamin J. Capoccia, BSc, Louisa Wirthlin, BSc, Rebecca Shepherd, MD, Kevin O’Dell, Jan A. Nolta, PhD, Daniel C. Link, MD, David A. Hess, PhD

Blood (2005) 106 (11): 2663.

https://doi.org/10.1182/blood.V106.11.2663.2663

Published: 2005

Journal Articles

AMD3100 and G-CSF Mobilize Angiogenic Cells into the Blood of Healthy Donors.

Rebecca M. Shepherd, MD, Benjamin J. Capoccia, Steven M. Devine, MD, David A. Ingram, MD, Daniel C. Link, MD

Blood (2005) 106 (11): 3022.

https://doi.org/10.1182/blood.V106.11.3022.3022

Published: 2005

Journal Articles

A Comparison of the Ability of AMD3100 Versus G-CSF to Induce Angiogenesis and Mobilize Endothelial Progenitor Cells (EPCs).

Benjamin J. Capoccia, B.S., Rebecca M. Shepherd, M.D., Hasan Guven, M.D., Steven M. Devine, M.D., Daniel C. Link, M.D.

Blood (2004) 104 (11): 3597.

https://doi.org/10.1182/blood.V104.11.3597.3597

Published: 2004

NARROW

AO-176, a Differentiated Clinical-Stage Anti-CD47 Antibody, Demonstrates Potent Anti-Tumor Activity across Multiple Preclinical Models of B Cell Neoplasms

Pre-Clinical Combination of AO-176, a Highly Differentiated Clinical Stage CD47 Antibody, with Either Azacitidine or Venetoclax Significantly Enhances DAMP Induction and Phagocytosis of Acute Myeloid Leukemia

Dual-Function Anti-CD47mAbs Induce Tumor Cell Death and Promote Phagocytosis Resulting in Enhanced in Vivo Efficacy

Revascularization of ischemic limbs after transplantation of human bone marrow cells with high aldehyde dehydrogenase activity

Conditioning of Monocytes in the Bone Marrow by Inflammatory Cytokines Inhibits Their Angiogenic Potential at Peripheral Sites of Ischemia

The Inflammatory Subset of Monocytes Stimulates Angiogenesis at Sites of Ischemia by Altering the Balance of Pro- and Anti-Inflammatory Cytokines.

Aldehyde Dehydrogenase-Activity Purifies Multiple Hemangiogenic Lineages That Accelerate Vascularization of Ischemic Tissue through Paracrine Support of Neovessel Formation.

Angiogenic cells can be rapidly mobilized and efficiently harvested from the blood following treatment with AMD3100

The Differential Role of Stromal Derived Factor-1 (SDF-1) and Monocyte Chemoattractant Protein-1 (MCP-1) in the Recruitment of Angiogenic Cells to Ischemic Tissue.

G-CSF and AMD3100 mobilize monocytes into the blood that stimulate angiogenesis in vivo through a paracrine mechanism

Bone Marrow-Derived Aldehyde Dehdrogenase Expressing Cells Possess Endothelial Progenitor Function in Addition to Hematopoietic Repopulating Ability and Aid in Blood Flow Recovery after Acute Ischemic Injury.

AMD3100 and G-CSF Mobilize Angiogenic Cells into the Blood of Healthy Donors.

A Comparison of the Ability of AMD3100 Versus G-CSF to Induce Angiogenesis and Mobilize Endothelial Progenitor Cells (EPCs).

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American Society of Hematology

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ASH Publications

American Society of Hematology

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