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Bao Nguyen, M.S.
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Journal Articles

Arsenic Trioxide Synergizes with FLT3 Tyrosine Kinase Inhibitors to Kill FLT3-ITD + Leukemic Cells through Depressed Production and Degradation of FLT3 Protein

Kozo Nagai, MD PhD, Lihong Hou, MD PhD, Li Li, MD PhD, Bao Nguyen, M.S., Courtney M Shirley, PhD, Hayley S Ma, PhD, Mark J. Levis, MD PhD, Amy S. Duffield, MD PhD, Donald Small, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1568.
https://doi.org/10.1182/blood.V128.22.1568.1568
Published: 2016
Journal Articles

FLT3 Inhibition and Retinoid Signaling Overcome Stromal Protection to Target FLT3/ITD-Expressing Leukemia Stem Cells in the Bone Marrow Microenvironment

Hayley S Ma, PhD, Megan E McCray, BA, Courtney M Shirley, PhD, Amy S. Duffield, MD PhD, J Kyle Bruner, Li Li, PhD, Bao Nguyen, M.S., Sarah Greenblatt, PhD, Eric Jung, BS, Peter D. Aplan, MD, Richard J Jones, MD, Donald Small, MD PhD, Gabriel Ghiaur, MD PhD
Journal: Blood
Blood (2015) 126 (23): 790.
https://doi.org/10.1182/blood.V126.23.790.790
Published: 2015
Journal Articles

Dnmt3a Deletion Cooperates with the Flt3-ITD Mutation to Drive Leukemogenesis in a Murine Model

Jennifer L Poitras, BS, Diane Heiser, PhD, Li Li, PhD, Bao Nguyen, M.S., Amy S. Duffield, MD PhD, Christopher Gamper, MD PhD, Donald Small, MD PhD
Journal: Blood
Blood (2014) 124 (21): 3568.
https://doi.org/10.1182/blood.V124.21.3568.3568
Published: 2014
Journal Articles

TTT-3002 Is Active Against Relapsed/Refractory AML Patient Bone Marrow With FLT3 TKI-Resistance Mutations At Residue D835

Hayley S Ma, Ph.D., Bao Nguyen, M.S., Mark Levis, MD, PhD, Allen B Williams, PhD, Donald Small, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 3818.
https://doi.org/10.1182/blood.V122.21.3818.3818
Published: 2013
Journal Articles

TTT-3002 Is a Novel FLT3 Tyrosine Kinase Inhibitor That Has the Potential to Overcome Some of the Limitations of Current FLT3 Inhibitors in Treatment of Acute Myeloid Leukemia

Hayley S Wall, B.S., Bao Nguyen, M.S., Li Li, PhD, Sarah M Greenblatt, PhD, Patrick Brown, MD, Mark J. Levis, MD, PhD, Donald Small, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 866.
https://doi.org/10.1182/blood.V120.21.866.866
Published: 2012
Journal Articles

Knock-in of a FLT3 Internal Tandem Duplication Mutation Cooperates with a NUP98-HOXD13 Fusion to Generate Acute Myeloid Leukemia

Sarah M Greenblatt, Li Li, PhD, Christopher Slape, PhD, Rachel L Novak, PhD, Amy S. Duffield, MD, PhD, Bao Nguyen, M.S., David Huso, D.V.M., Ph.D., Michael J. Borowitz, MD, PhD, Peter Aplan, MD, Donald Small, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 865.
https://doi.org/10.1182/blood.V118.21.865.865
Published: 2011
Journal Articles

Statin Treatment Prevents FLT3 Glycosylation and Overcomes Resistance to FLT3 Tyrosine Kinase Inhibitors

Allen Williams, PhD, Li Li, PhD, Bao Nguyen, M.S., Patrick Brown, MD, Mark J. Levis, MD, PhD, Donald Small, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 1421.
https://doi.org/10.1182/blood.V118.21.1421.1421
Published: 2011
Journal Articles

Statin Treatment Inhibits FLT3 Signaling by Preventing Glycosylation of the Mature Receptor and Leads to Cell Death In Mutant FLT3 Expressing Cells

Allen Williams, PhD, Bao Nguyen, M.S., Li Li, PhD, Patrick Brown, MD, Mark J. Levis, MD, PhD, Donald Small, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 779.
https://doi.org/10.1182/blood.V116.21.779.779
Published: 2010
Journal Articles

EB10, an Anti-FLT3 Monoclonal Antibody, Prolongs Survival and Reduces NOD/SCID Engraftment of AML Cell Lines and Primary Blasts.

Obdulio Piloto, B.S., Mark Levis, M.D./Ph.D., Li Li, Ph.D., Bao Nguyen, M.S., Kyu-Tae Kim, Ph.D., David Huso, Ph.D., Yiwen Li, Ph.D., Hongli Li, Ph.D., Mei-Nai Wang, Ph.D., Larry Witte, Ph.D., Daniel J. Hicklin, Ph.D., Donald Small, M.D./Ph.D.
Journal: Blood
Blood (2004) 104 (11): 2534.
https://doi.org/10.1182/blood.V104.11.2534.2534
Published: 2004
Journal Articles

EB10, an Anti-FLT3 Monoclonal Antibody, Selectively Targets ALL Cell Lines and Primary ALL Blasts without Interfering with Normal Hematopoiesis.

Obdulio Piloto, B.S., Patrick Brown, M.D., Li Li, Ph.D., Bao Nguyen, M.S., Kyu-Tae Kim, Ph.D., David Huso, Ph.D., Yiwen Li, Ph.D., Hongli Li, Ph.D., Mei-Nai Wang, Ph.D., Larry Witte, Ph.D., Daniel J. Hicklin, Ph.D., Donald Small, M.D./Ph.D.
Journal: Blood
Blood (2004) 104 (11): 2744.
https://doi.org/10.1182/blood.V104.11.2744.2744
Published: 2004
Journal Articles

FLT3/ITD Expression Increases Expansion, Survival and Entry into Cell Cycle of Human Hematopoietic Stem Cells.

Li Li, Ph.D., Obdulio Piloto, B.S., Kyu-Tae Kim, Ph.D., Zhaohui Ye, M.S., Bao Nguyen, M.S., Xiaobing Yu, M.D., Ph.D., Mark Levis, M.D., Ph.D., Linzhao Cheng, Ph.D., Donald Small, M.D., Ph.D.
Journal: Blood
Blood (2004) 104 (11): 484.
https://doi.org/10.1182/blood.V104.11.484.484
Published: 2004