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Ashwin Unnikrishnan, PhD
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Journal Articles

Identification of Recurrent Alternative RNA Splicing in Adverse-Risk Acute Myeloid Leukemia

Govardhan Anande, Ashwin Unnikrishnan, PhD, Nandan Deshpande, PhD, Sylvain Mareschal, Aarif M. N. Batcha, Tobias Herold, MD, Sören Lehmann, MD PhD, Marc Wilkins, PhD, Jason Wong, PhD, John Pimanda, MBBS, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 457.
https://doi.org/10.1182/blood-2019-129537
Published: 2019
Journal Articles

In Vivo Assessment of Intracellular Dynamics Comparing Injection Versus Oral Azacitidine in a Phase IIb Investigator Initiated Clinical Trial

Ashwin Unnikrishnan, PhD, Xin Ying Lim, PhD, Swapna Joshi, Andrea C. Nunez, PhD, Lachlin Vaughan, MBBS, BSc, FRACP, FRCPA, Russell Pickford, PhD, Sally Hough, Sarah Davidson, Chun Fong, Melita Kenealy, MD, Devendra K Hiwase, MBBS, MD FRACP, FRCPA, PhD, Leonardo Pasalic, MBBS, PhD, Soma Mohammed, Linda Lee, PhD, Freda H. Passam, MD PhD, Kevin Spring, PhD, Patricia Rebeiro, MD, Silvia Ling, MBBS, PhD, Stephen Fuller, MBBS, PhD, Peter Presgrave, MBBS, Fernando Roncolato, BMed, FRACP, FRCPA, Stephen Larsen, MBBS, PhD FRACP, FRCPA, Anoop K Enjeti, MBBS,FRCPA, FRACP,PhDMD,MRCP, William S. Stevenson, MBBS, PhD, Campbell Tiley, MBBS, FRACP, Peter J Campbell, Charlotte Lemech, MD FRACP, Jake Olivier, PhD, Mark Hertzberg, MD MBBS, PhD, Mark N. Polizzotto, MBBS, FRACP, FRCPA, John Pimanda, MBBS, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4247.
https://doi.org/10.1182/blood-2019-123921
Published: 2019
Journal Articles

Small-Molecule Inhibition of PRMT5 Induces Translational Stress and p53 in JAK2V617F Mutant Myeloproliferative Neoplasms

Stefan Sonderegger, PhD MSc, Loretta Cerruti, BSc, Cedric Tremblay, PhD, Emma Toulmin, PhD, Jesslyn Saw, BSc, Tom Nebl, PhD, Katherine M Hannan, PhD, Steven W. Lane, MD PhD, Hendrik Falk, PhD, Ashwin Unnikrishnan, PhD, Paul Stupple, PhD, Ian Street, PhD, Stephen Jane, MDPhD, Rachel Altura, PhD, Benjamin Nicholson, PhD, David J. Curtis, MBBS,PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 53.
https://doi.org/10.1182/blood-2018-99-118406
Published: 2018
Journal Articles

Granulomonocytic Progenitors (GMPs) Are Key Target Cells of Azacitidine in MDS and AML

Ashfaq Ali, PhD, Justine Penneroux, Reinaldo Dal Bello Jr, Aline Massé, Samuel Quentin, Ashwin Unnikrishnan, PhD, Lucie Hernandez, Emmanuel Raffoux, MD, Raouf Benabelali, Aline Renneville, MDPhD, Claude Preudhomme, PharmD, PhD, John Pimanda, PhDFRACP,FRCPA,MBBS, Herve Dombret, MD, Jean Soulier, MDPhD, Pierre Fenaux, MD PhD, Emmanuelle Clappier, PharmD,PhD, Lionel Ades, MD PhD, Raphael Itzykson, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 587.
https://doi.org/10.1182/blood.V130.Suppl_1.587.587
Published: 2017
Journal Articles

An Integrative Genomics Approach Uncovers the Basis of Resistance to AZA Therapy in MDS and CMML

Ashwin Unnikrishnan, PhD, Elli Papaemmanuil, PhD, Dominik Beck, PhD, Arjun Verma, B.Sc., Ashu Kumari, PhD, Laura A. Richards, Kathy Knezevic, Vashe Chandrakanthan, PhD, Julie A.I. Thoms, PhD, Melinda L. Tursky, PhD, Yizhou Huang, Sally Galbraith, PhD, Austin G. Kulasekararaj, MBBS, MD MRCP, FRCPath, Magnus Tobiasson, MD, Petter S. Woll, PhD, Andrea Pellagatti, PhD, Susan R. Wilson, PhD, Robert Lindeman, MD, Jacqueline Boultwood, PhD, Kevin Lynch, MBBS, Sten Eirik Jacobsen, Ghulam J Mufti, FRCP, FRCPath, Eva Hellstrom-Lindberg, MD PhD, Karen Lee Mackenzie, PhD, Jason W.H. Wong, PhD, Peter J Campbell, MD PhD, John E. Pimanda, MDPhD
Journal: Blood
Blood (2015) 126 (23): 710.
https://doi.org/10.1182/blood.V126.23.710.710
Published: 2015
Journal Articles

Identification of a Prognostic Gene Expression Signature for AZA Response in MDS and CMML Patients

Ashwin Unnikrishnan, PhD, Dominik Beck, PhD, Arjun Verma, Laura A Richards, Julie A I Thoms, PhD, Ashu Kumari, PhD, Sally Galbraith, PhD, Austin Kulasekararaj, Magnus Tobiasson, MD, Petter S Woll, PhD, Andrea Pellagatti, PhD, Elli Papaemmanuil, PhD, Susan R Wilson, PhD, Robert Lindeman, MD, Peter J Campbell, PhD, Jacqueline Boultwood, PhD, Kevin Lynch, MBBS, Sten Eirik W Jacobsen, MD PhD, Ghulam J. Mufti, DM, FRCP, FRCPath, Eva Hellstrom-Lindberg, MD PhD, Karen L MacKenzie, PhD, Jason WH Wong, PhD, John E Pimanda, MD PhD
Journal: Blood
Blood (2014) 124 (21): 4601.
https://doi.org/10.1182/blood.V124.21.4601.4601
Published: 2014
Journal Articles

Mutations in Histone Modulators and HOXA5 Methylation Levels Affects Survival in Azacitidine Treated MDS Patients

Magnus Tobiasson, MD, Mohsen Karimi, Marios Dimitriou, Ying Qu, MDM.Sc, Andreas Lennartsson, PhD, Hani Abdulkadir Ali, Ashwin Unnikrishnan, PhD, Martin Jadersten, MDPhD, Monika Jansson, Asmaa Ben Azenkoud, John E Pimanda, MD PhD, Karl Ekwall, Prof, Johanna Ungerstedt, MD PhD, Soren Lehmann, MD PhD, Eva Hellstrom-Lindberg, MD PhD
Journal: Blood
Blood (2014) 124 (21): 4613.
https://doi.org/10.1182/blood.V124.21.4613.4613
Published: 2014