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Ari Friedland
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Journal Articles

Durable Multiplex Epigenetic Editing for Generation of Allogeneic CAR T without Chromosomal Rearrangements

Jamie Schafer, Justin Trombley, Benjamin Hallisey, Kunza Ahmad, Scott Clarkson, Thijs Udo, McKensie Collins, Laura Kehoe, Erica Hildebrand, Kaylie Schneider, Kuo-Chan Hung, Ricardo N Ramirez, Mary Morrison, Morgan Maeder, Sahar Abubucker, Ari Friedland, Pietro Spinelli, Vic Myer, Aron Jaffe
Journal: Blood
Blood (2023) 142 (Supplement 1): 3446.
https://doi.org/10.1182/blood-2023-179282
Published: 2023
Journal Articles

Comparative Studies Reveal Robust HbF Induction By Editing of HBG1/2 Promoters or BCL11A Erythroid-Enhancer in Human CD34+ Cells but That BCL11A Erythroid-Enhancer Editing Is Associated with Selective Reduction in Erythroid Lineage Reconstitution in a Xenotransplantation Model

Kai-Hsin Chang, PhD, Minerva Sanchez, Jack Heath, Edouard deDreuzy, PhD, Scott Haskett, MS, Abigail Vogelaar, Kiran Gogi, Jen Da Silva, Tongyao Wang, Andrew Sadowski, Gregory Gotta, Jamaica Siwak, Ramya Viswanathan, Katherine Loveluck, Hoson Chao, Eric Tillotson, Aditi Chalishazar, MS, Abhishek Dass, Frederick Ta, Emily Brennan, Diana Tabbaa, Eugenio Marco, PhD, John A Zuris, PhD, Deepak Reyon, PhD, Meltem Isik, PhD, Ari Friedland, PhD, Terence Ta, PhD, Fred Harbinski, Georgia Giannoukos, PhD, Sandra Teixeira, PhD, Christopher J Wilson, PhD, Charlie Albright, PhD, Haiyan Jiang, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 409.
https://doi.org/10.1182/blood-2018-99-114780
Published: 2018