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Journal Articles

Profiling of Circulating Exosomes in Patients with Waldenström Macroglobulinemia

Juliette Marie Charlotte Bouyssou, BSc, MSc, Yosra Aljawai, MSc, Amir Yosef, MD, Salomon Manier, MD, Ragyie Rawal, Katsutoshi Kokubun, PhD, Adriana Perilla Glen, MBA, Antonio Sacco, BS, RN, Jorge J. Castillo, MD, Steven P Treon, MD PhD, Aldo M. Roccaro, MD PhD, Marzia Capelletti, PhD MMSc, Olivier Hermine, MD PhD, Irene M. Ghobrial, MD

Blood (2016) 128 (22): 2940.

https://doi.org/10.1182/blood.V128.22.2940.2940

Published: 2016

Journal Articles

Driver Mutation in Waldenstrom's Macroglobullinemia and Their Clonal Heterogeneity during Progression and Relapse

Jihye Park, PhD, Antonio Sacco, BS, RN, Salomon Manier, MD, Karma Salem, MD, Mira Mashood, MD, Adriana Perilla-Glen, MBA, Yosra Aljawai, Jiantao Shi, PhD, Eliezer Van Allen, MD, Marzia Capelletti, PhD MMSc, Irene M. Ghobrial, MD, Aldo M. Roccaro, MD PhD

Blood (2016) 128 (22): 1092.

https://doi.org/10.1182/blood.V128.22.1092.1092

Published: 2016

Journal Articles

In Vivo Genome-Wide Crispr Library Screen in a Xenograft Mouse Model of Tumor Growth and Metastasis of Multiple Myeloma

Yujia Shen, PhD, Salomon Manier, MD, Jihye Park, PhD, Yuji Mishima, PhD, Marzia Capelletti, PhD MMSc, Aldo M. Roccaro, MD PhD, Daisy Huynh, BS, MS, Antonio Sacco, BS, Sabrin Tahri, BS, Glenn Cowley, PhD, John G Doench, PhD, David Root, PhD, Irene M. Ghobrial, MD

Blood (2016) 128 (22): 1137.

https://doi.org/10.1182/blood.V128.22.1137.1137

Published: 2016

Journal Articles

Dual Conditional Loss of BLIMP-1 and p53 in B-Cells Drives B-Cell Lymphomagenesis

Antonio Sacco, BS, Yawara Kawano, MD PhD, Michele Moschetta, MD, Jihye Park, PhD, Oksana Zavidij, PhD, Michaela Reagan, PhD, Yuji Mishima, PhD, Elizabeth A. Morgan, MD, Satoshi Takagi, PhD, Salomon Manier, MD, Luisa Imberti, MD, Giuseppe Rossi, MD, Kwok Wong, MD, Ruben D. Carrasco, MD PhD, Irene M. Ghobrial, MD, Aldo M. Roccaro, MD PhD

Blood (2016) 128 (22): 4169.

https://doi.org/10.1182/blood.V128.22.4169.4169

Published: 2016

Journal Articles

Whole-Exome Sequencing and Targeted Deep Sequencing of cfDNA Enables a Comprehensive Mutational Profiling of Multiple Myeloma

Blood (2016) 128 (22): 197.

https://doi.org/10.1182/blood.V128.22.197.197

Published: 2016

Journal Articles

Roundabout 1 (ROBO1)/SLIT2 Is a Novel Signaling Pathway in Multiple Myeloma Promoting Survival and Bone Marrow Niche Interaction

Giada Bianchi, MD, Peter G. Czarnecki, MD, Aldo M. Roccaro, MD PhD, Antonio Sacco, BS, Yawara Kawano, MD PhD, Mehmet K. Samur, PhD, Annamaria Gulla, MD, Yu-Tzu Tai, PhD, Irene M. Ghobrial, MD, Ruben D. Carrasco, MD PhD, Kenneth C. Anderson, MD

Blood (2016) 128 (22): 485.

https://doi.org/10.1182/blood.V128.22.485.485

Published: 2016

Journal Articles

In Vivo Analysis of Clonal Evolution of Multiple Myeloma

Yuji Mishima, PhD, Jiantao Shi, PhD, Michele Moschetta, MD, Yujia Shen, PhD, Salomon Manier, MD, Aldo M. Roccaro, MD PhD, Francois Mercier, MD FRCPC, Satoshi Takagi, PhD, Yawara Kawano, MD PhD, Shokichi Tsukamoto, MD PhD, Ilyas Sahin, Antonio Sacco, BS, Kiyohiko Hatake, MD PhD, Franziska Michor, PhD, David T. Scadden, MD, Irene M. Ghobrial, MD

Blood (2016) 128 (22): 799.

https://doi.org/10.1182/blood.V128.22.799.799

Published: 2016

Journal Articles

Whole Exome Sequencing and Targeted Sequencing Reveal the Heterogeneity of Genomic Evolution and Mutational Profile in Smoldering Multiple Myeloma

Karma Salem, MD, Jihye Park, PhD, Claudia Freymond, MSc, Marzia Capelletti, PhD MMSc, Daisy Huynh, BS, MS, Antonio Sacco, BS, RN, Adriana Perilla Glen, MBA, Aaron M. Caola, BS, Patrick Henrick, BS, Eliezer Van Allen, MD, David Liu, MD, Aldo M. Roccaro, MD PhD, Nikhil C Munshi, MD, Gad Getz, PhD, Irene M. Ghobrial, MD, Salomon Manier, MD

Blood (2016) 128 (22): 237.

https://doi.org/10.1182/blood.V128.22.237.237

Published: 2016

Journal Articles

Microrna-138 Regulates Osteogenic Differentiation and Its Inhibition Presents a Novel Therapeutic Line to Prevent Bone Lytic Lesions in Multiple Myeloma

Shokichi Tsukamoto, MD PhD, Karma Salem, MD, Salomon Manier, MD, Michaela R. Reagan, PhD, Daisy Huynh, BS, MS, Adriana Perilla-Glen, MBA, Antonio Sacco, BS, Oksana Zavidij, PhD, Mahshid Rahmat, PhD, Satoshi Takagi, PhD, Yawara Kawano, MD PhD, Katsutoshi Kokubun, PhD, Charlotte Albæk Thrue, MSc, Andreas Petri, PhD MSc, David M. Dorfman, MD PhD, Aldo M. Roccaro, MD PhD, Marzia Capelletti, PhD MMSc, Sakari Kauppinen, PhD, Irene M. Ghobrial, MD

Blood (2016) 128 (22): 4483.

https://doi.org/10.1182/blood.V128.22.4483.4483

Published: 2016

Journal Articles

Mutational Profile and Prognostic Relevance of Circulating Tumor Cells in Multiple Myeloma

Blood (2015) 126 (23): 23.

https://doi.org/10.1182/blood.V126.23.23.23

Published: 2015

Journal Articles

Characterization of the Role of Regulatory T Cells (Tregs) in Inducing Progression of Multiple Myeloma

Yawara Kawano, MDPhD, Michele Moschetta, MD, Katsutoshi Kokubun, PhD, Pavlo Lukyanchykov, MD, Esilida Sula Karreci, MD, Salomon Manier, MD, Shokichi Tsukamoto, MD PhD, Satoshi Takagi, PhD, Jiantao Shi, Michaela R. Reagan, PhD, Daisy Huynh, BS, MS, Antonio Sacco, BS, David M. Dorfman, MD PhD, Marta Chesi, PhD, Peter Leif Bergsagel, MD PhD, Aldo M Roccaro, MD PhD, Jamil Azzi, MD, Irene M. Ghobrial, MD

Blood (2015) 126 (23): 502.

https://doi.org/10.1182/blood.V126.23.502.502

Published: 2015

Journal Articles

Platelets/Megakaryocytes Are Critical Regulators of Tumor Progression in Multiple Myeloma

Satoshi Takagi, PhD, Shokichi Tsukamoto, MD PhD, Yawara Kawano, MDPhD, Michele Moschetta, MD, Yuji Mishima, PhD, Katsutoshi Kokubun, PhD, Salomon Manier, MD, Karma Salem, MD, Daisy Huynh, BS, MS, Antonio Sacco, BS, Aldo M Roccaro, MD PhD, Kelly Elizabeth Johnson, PhD, Elisabeth M. Battinelli, MD PhD, Irene M. Ghobrial, MD

Blood (2015) 126 (23): 1793.

https://doi.org/10.1182/blood.V126.23.1793.1793

Published: 2015

Journal Articles

MYC Regulation Via the LIN28B/Let-7 Axis in Multiple Myeloma

Salomon Manier, MD, John Powers, PhD, Antonio Sacco, BS, Siobhan Glavey, MD, Daisy Huynh, BS, MS, Michaela R. Reagan, PhD, Karma Salem, MD, Michele Moschetta, MD, Yuji Mishima, PhD, Xavier Leleu, MD PhD, Aldo M Roccaro, MD PhD, George Q. Daley, MD PhD, Irene M. Ghobrial, MD

Blood (2015) 126 (23): 1755.

https://doi.org/10.1182/blood.V126.23.1755.1755

Published: 2015

Journal Articles

Circulating Exosomal microRNAs Are Prognostic Markers in Multiple Myeloma

Salomon Manier, MD, Herve Avet-Loiseau, Federico Campigotto, MS, Karma Salem, MD, Daisy Huynh, BS, MS, Siobhan Glavey, MD, Antonio Sacco, BS, Aldo M Roccaro, MD PhD, Stephane Minvielle, Philippe Moreau, MD PhD, Thierry Facon, Xavier Leleu, MD PhD, Edie A. Weller, PhD, Irene M. Ghobrial, MD

Blood (2015) 126 (23): 1770.

https://doi.org/10.1182/blood.V126.23.1770.1770

Published: 2015

Journal Articles

A New Model for Studying the Dissemination of Myeloma Cells throughout the Bone Marrow Using Embryonic Zebrafish

Aldo M Roccaro, MD PhD, Antonio Sacco, BS, Dongdong Ma, MD PhD, Jiantao Shi, Yuji Mishima, PhD, Michele Moschetta, MD, Robert I. Handin, MD, Irene M. Ghobrial, MD

Blood (2015) 126 (23): 915.

https://doi.org/10.1182/blood.V126.23.915.915

Published: 2015

Journal Articles

Novel CXCR4-Targeted Therapy to Inhibit Multiple Myeloma Bone Dissemination

Aldo M Roccaro, MD PhD, Antonio Sacco, BS, Michele Moschetta, MD, Yuji Mishima, PhD, Patricia Maiso, PhD, Daisy Huynh, MPS, Marco Chiarini, MSc, Pina M. Cardarelli, PhD, Lewis Cohen, MD MS, Michelle Kuhne, PhD, Irene M. Ghobrial, MD

Blood (2014) 124 (21): 4709.

https://doi.org/10.1182/blood.V124.21.4709.4709

Published: 2014

Journal Articles

Early Trafficking of Bone Marrow Derived-Endothelial Progenitor Cells Promotes Multiple Myeloma Progression

Michele Moschetta, MD, Yuji Mishima, PhD, Yawara Kawano, MD PhD, Yosra Aljawai, MS, Bruno Paiva, PhD, Luis Palomera, MD, Arianna Calcinotto, Unitt L. Christine, BSc, Ilyas Sahin, MD, Antonio Sacco, BS, Siobhan Glavey, MD, Michaela R. Reagan, PhD, Salomon Manier, MD, Peter Leif Bergsagel, MD PhD, Marta Chesi, PhD, Matteo Bellone, MD, Aldo M Roccaro, MD PhD, Irene M. Ghobrial, MD

Blood (2014) 124 (21): 4719.

https://doi.org/10.1182/blood.V124.21.4719.4719

Published: 2014

Journal Articles

Citron Rho-Interacting Serine/Threonine kinase (CIT) Is a Novel Therapeutic Target in Multiple Myeloma Cells

Yawara Kawano, MDPhD, Ilyas Sahin, MD, Michele Moschetta, MD, Jinhua Wang, Salomon Manier, MD, Siobhan Glavey, MD, Yuji Mishima, PhD, Katsutoshi Kokubun, PhD, Shokichi Tsukamoto, MD PhD, Antonio Sacco, BS, Kenneth C. Anderson, MD, Aldo M Roccaro, MD PhD, Nathanael S. Gray, PhD, Irene M. Ghobrial, MD

Blood (2014) 124 (21): 3430.

https://doi.org/10.1182/blood.V124.21.3430.3430

Published: 2014

Journal Articles

Dissecting the Mechanisms of Activity of SLAMF7 and the Targeting Antibody Elotuzumab in Multiple Myeloma

Siobhan Glavey, MD, Michaela Reagan, PhD, Salomon Manier, MD, Michele Moschetta, MD, Yawara Kawano, MDPhD, Antonio Sacco, BS, Aldo M Roccaro, MD PhD, Michael Robbins, BS, Irene M. Ghobrial, MD

Blood (2014) 124 (21): 3431.

https://doi.org/10.1182/blood.V124.21.3431.3431

Published: 2014

Journal Articles

Proteomic Characterization of the Multiple Myeloma Bone Marrow Extracellular Matrix

Siobhan Glavey, MD, Alexandra Naba, PhD, Salomon Manier, MD, Manuela Gambella, Alberto Rocci, MD, Antonio Sacco, BS, John M. Asara, PhD, Michele Moschetta, MD, Michaela R. Reagan, PhD, Yuji Mishima, PhD, Yawara Kawano, MD PhD, Aldo M Roccaro, MD PhD, Antonio Palumbo, MD, Richard O. Hynes, PhD, Irene M. Ghobrial, MD

Blood (2014) 124 (21): 2051.

https://doi.org/10.1182/blood.V124.21.2051.2051

Published: 2014

NARROW

Profiling of Circulating Exosomes in Patients with Waldenström Macroglobulinemia

Driver Mutation in Waldenstrom's Macroglobullinemia and Their Clonal Heterogeneity during Progression and Relapse

In Vivo Genome-Wide Crispr Library Screen in a Xenograft Mouse Model of Tumor Growth and Metastasis of Multiple Myeloma

Dual Conditional Loss of BLIMP-1 and p53 in B-Cells Drives B-Cell Lymphomagenesis

Whole-Exome Sequencing and Targeted Deep Sequencing of cfDNA Enables a Comprehensive Mutational Profiling of Multiple Myeloma

Roundabout 1 (ROBO1)/SLIT2 Is a Novel Signaling Pathway in Multiple Myeloma Promoting Survival and Bone Marrow Niche Interaction

In Vivo Analysis of Clonal Evolution of Multiple Myeloma

Whole Exome Sequencing and Targeted Sequencing Reveal the Heterogeneity of Genomic Evolution and Mutational Profile in Smoldering Multiple Myeloma

Microrna-138 Regulates Osteogenic Differentiation and Its Inhibition Presents a Novel Therapeutic Line to Prevent Bone Lytic Lesions in Multiple Myeloma

Mutational Profile and Prognostic Relevance of Circulating Tumor Cells in Multiple Myeloma

Characterization of the Role of Regulatory T Cells (Tregs) in Inducing Progression of Multiple Myeloma

Platelets/Megakaryocytes Are Critical Regulators of Tumor Progression in Multiple Myeloma

MYC Regulation Via the LIN28B/Let-7 Axis in Multiple Myeloma

Circulating Exosomal microRNAs Are Prognostic Markers in Multiple Myeloma

A New Model for Studying the Dissemination of Myeloma Cells throughout the Bone Marrow Using Embryonic Zebrafish

Novel CXCR4-Targeted Therapy to Inhibit Multiple Myeloma Bone Dissemination

Early Trafficking of Bone Marrow Derived-Endothelial Progenitor Cells Promotes Multiple Myeloma Progression

Citron Rho-Interacting Serine/Threonine kinase (CIT) Is a Novel Therapeutic Target in Multiple Myeloma Cells

Dissecting the Mechanisms of Activity of SLAMF7 and the Targeting Antibody Elotuzumab in Multiple Myeloma

Proteomic Characterization of the Multiple Myeloma Bone Marrow Extracellular Matrix

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American Society of Hematology

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