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Antonio R. Lucena-Araujo, PhD
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Journal Articles

Reduced SLIT2 Are Associated with Increased Cell Proliferation and Arsenic Trioxide Resistance in APL Cells

Isabel Weinhäuser, MSc, Diego A Pereira-Martins, MSc, Luíse A A Simões, BSc, César Alexander Ortiz Rojas, BSc, Thiago Mantello Bianco, MSc, Cleide Lucia Silva, MSc, Mariane Cristina Do Nascimento, BSc, Lorena Lobo Figueiredo-Pontes, MD PhD, Antonio R. Lucena-Araujo, PhD, Eduardo M Rego, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5165.
https://doi.org/10.1182/blood-2019-131496
Published: 2019
Journal Articles

Arsenic Trioxide Abrogate MN1 Mediated RA-Resistance in Acute Promyelocytic Leukemia

Diego A Pereira-Martins, MSc, Juan L Coelho-Silva, BSc, MSc, Isabel Weinhäuser, MSc, Luisa C A Koury, MD, Raul Antônio Morais Melo, MD PhD, Rosane Bittencourt, Katia B Pagnano, MD PhD, Ricardo Pasquini, MD, Elenaide C. Nunes, MD, Evandro Maranhão Fagundes, MD, Ana Beatriz F. Gloria, MD, Fabio R. Kerbauy, MD, Armand Keating, MD, Martin S. Tallman, MD, Raul Ribeiro, MD, Richard Dillon, MA, PhD MRCP, FRCPath, Arnold Ganser, MD, Michael Heuser, MD, Bob Löwenberg, MD PhD, Peter Valk, PhD, Miguel A. Sanz, Nancy Berliner, MD, Antonio R. Lucena-Araujo, PhD, Eduardo M Rego, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5166.
https://doi.org/10.1182/blood-2019-131595
Published: 2019
Journal Articles

Molecular-Based Score Inspired on Metabolic Signature Improves Prognostic Stratification for Myelodysplastic Syndrome

Juan L Coelho-Silva, BSc, MSc, Douglas R. A. Silveira, Diego A Pereira-Martins, MSc, César Alexander Ortiz Rojas, BSc, Antonio R. Lucena-Araujo, PhD, Eduardo M Rego, MD PhD, João Agostinho Machado-Neto, PhD, Israel Bendit, MD PhD, Vanderson Rocha, MD PhD, Fabiola Traina, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4257.
https://doi.org/10.1182/blood-2019-132141
Published: 2019
Journal Articles

MN1 Expression Is an Indepedent Prognostic Marker in FLT3-Mutated Acute Myeloid Leukemia and Is Involved in the Resistance to FLT3 Inhibitors

Diego A Pereira-Martins, MSc, Juan L Coelho-Silva, BSc, MSc, Isabel Weinhäuser, MSc, Carol Hassibe Thomé, César Alexander Ortiz Rojas, BSc, Luíse A A Simões, BSc, Fabiola Traina, MD PhD, Michael Heuser, MD, Arnold Ganser, MD, Antonio R. Lucena-Araujo, PhD, Eduardo M Rego, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1403.
https://doi.org/10.1182/blood-2019-131542
Published: 2019
Journal Articles

Up-Regulation of Mir-21 and Mir-130a and Serum Leptin Levels on Leg Ulcers Development in Sickle Cell Anemia

Thais Helena Chaves Batista, Rodrigo Marcionilo Santana, Marcondes José de Vasconcelos Costa Sobreira, BSc, Gabriela da Silva Arcanjo, BSc, Diego Arruda Falcao, PhD, Diego A Pereira-Martins, MD, Aderson da Silva Araujo, MD PhD, Fernando Ferreira Costa, MD PhD, Mario José Abdalla Saad, PhD MD, Bruno de Melo Carvalho, PhD, Luydson Richardson Silva Vasconcelos, PhD, Antonio R. Lucena-Araujo, PhD, Marcos Andre Cavalcanti Bezerra, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 975.
https://doi.org/10.1182/blood-2019-132043
Published: 2019
Journal Articles

Slit-Robo Pathway Is Clinically Relevant and May Represent a Potential Target in Acute Promyelocytic Leukemia

Isabel Weinhäuser, MSc, Diego Antonio Pereira-Martins, MSc, Cesar Ortiz, BS, Josiane Lilian Schiavinato, PhD, Camila Bonaldo, Luisa C Koury, Virginia Mara De Deus Wagatsuma, PhD, Raul Antônio Morais Melo, MD PhD, Rosane Bittencourt, MD, Katia B Pagnano, MD, Evandro Maranhão Fagundes, MD, Ana Beatriz F. Gloria, MD, Fabio R. Kerbauy, MD, Maria de Lourdes Chauffaille, MD PhD, Ricardo Pasquini, MD, Martin S. Tallman, MD, Raul Ribeiro, MD, Richard Dillon, MA, PhD MRCP, FRCPath, Armand Keating, MD, Arnold Ganser, MD, Bob Lowenberg, MD, Peter Valk, PhD, Francesco Lo-Coco, MD, Miguel A. Sanz, MD, Nancy Berliner, MD, Antonio R. Lucena-Araujo, PhD, Eduardo Magalhães Rego, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1533.
https://doi.org/10.1182/blood-2018-99-115370
Published: 2018
Journal Articles

Metformintreatment Overcomes ATRA-Resistance in Acute Promyelocytic Leukemia and Increases FOXO3A Expression

Diego Antonio Pereira-Martins, MSc, Cesar Ortiz, BS, Pedro Luis Franca-Neto, MSc, Isabel Weinhäuser, MSc, Josiane Lilian Schiavinato, PhD, Patrícia Vianna Bonini Palma, BSc, Camila Bonaldo, Luisa C A Koury, MD, Mariane Cristina Do Nascimento, BSc, Raul Antônio Morais Melo, MD PhD, Rosane Bittencourt, MD, Katia B B Pagnano, MD PhD, Ricardo Pasquini, MD, Evandro Maranhão Fagundes, MD, Ana Beatriz F. Gloria, MD, Fabio R. Kerbauy, MD, Maria de Lourdes Chauffaille, MD PhD, Armand Keating, MD, Martin S. Tallman, MD, Raul Ribeiro, MD, Richard Dillon, MA, PhD MRCP, FRCPath, Arnold Ganser, MD, Bob Lowenberg, MD, Peter Valk, PhD, Francesco Lo-Coco, MD, Miguel A. Sanz, MD, Nancy Berliner, MD, Antonio R. Lucena-Araujo, PhD, Eduardo Magalhães Rego, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1532.
https://doi.org/10.1182/blood-2018-99-115068
Published: 2018
Journal Articles

KMT2E-Mediated Epigenetic Reprogramming Promotes the Sensitivity to All-Trans Retinoic Acid and Increases the Granulocytic Differentiation in AML Cells

Luciana Yamamoto Almeida, PhD, Isabel Weinhäuser, MSc, Diego Antonio Pereira-Martins, MSc, Josiane Lilian Schiavinato, PhD, Patrícia Vianna Bonini Palma, BSc, Camila Bonaldo, Cleide Lucia Silva, MSc, Juliana Oliveira Poltronieri, MSc, Larissa Cândido, MSc, Antonio R. Lucena-Araujo, PhD, Eduardo Magalhães Rego, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3838.
https://doi.org/10.1182/blood-2018-99-118478
Published: 2018
Journal Articles

NSD1 and NSD2 Transcriptional Levels Might Predict Clinical Outcome in AML Patients

Virginia Mara De Deus Wagatsuma, PhD, Diego Antonio Pereira-Martins, MSc, Mariane Cristina Do Nascimento, BSc, Silvia Elena Sanchez Mendoza, Antonio R. Lucena-Araujo, PhD, Aleide Lima, MSc, Felipe Saldanha-Araujo, PhD, Fabio Pitella, PhD, Fabiola Traina, MD PhD, Maria Isabel A Madeira, MSc, MD, Lorena Lobo Figueiredo-Pontes, MD PhD, Eduardo Magalhães Rego, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5257.
https://doi.org/10.1182/blood-2018-99-119411
Published: 2018
Journal Articles

Functional Analysis of the FOXO3 Gene on the Induction of Fetal Hemoglobin in K562 Cells

Flávia Peixoto Albuquerque, MD, Pedro Luis Franca-Neto, MSc, Rafael de Oliveira Franca, PhD, Aderson da Silva Araujo, PhD, Fernando F. Costa, MD, PhD, Marcos Bezerra, BSc, MSc, PhD, Antonio R. Lucena-Araujo, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2390.
https://doi.org/10.1182/blood-2018-99-111994
Published: 2018
Journal Articles

Combining Gene Mutation with Gene Expression Data Improves Outcomes Prediction in Acute Promyelocytic Leukemia

Antonio R. Lucena-Araujo, PhD, Diego A Pereira-Martins, MD, Luisa C A Koury, MD, Juan Luiz Coelho-Silva, BSc, MSc, Raul Antônio Morais Melo, MD PhD, Rosane Bittencourt, MD, Katia B Pagnano, MD, Ricardo Pasquini, MD, Carlos Chiattone, MD, Evandro Maranhão Fagundes, MD, Maria de Lourdes Chauffaille, MD PhD, Stanley L. Schrier, MD, Martin S. Tallman, MD, Raul C. Ribeiro, MD, David Grimwade, Arnold Ganser, MD, Bob Lowenberg, MD PhD, Francesco Lo Coco, MD, Miguel A. Sanz, MD, Nancy Berliner, MD, Eduardo Magalhães Rego, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2696.
https://doi.org/10.1182/blood.V130.Suppl_1.2696.2696
Published: 2017
Journal Articles

Association between Nuclear SET Domain ( NSD ) Protein Lysine Methyltransferases (KMT) Expression and Poor Prognosis in Acute Promyelocytic Leukemia (APL) Patients Treated with ATRA and Anthracycline Protocol

Virginia Mara De Deus Wagatsuma, PhD, Diego A Pereira-Martins, MD, Silvia Elena Sánchez Mendoza, MSc, Luisa C A Koury, MD, Mariane Cristina Nascimento, Raul Antônio Morais Melo, MD PhD, Rosane Bittencourt, MD, Katia B Pagnano, MD, Ricardo Pasquini, MD, Carlos Chiattone, MD, Evandro Maranhão Fagundes, MD, Maria de Lourdes Chauffaille, MD PhD, Antonio R. Lucena-Araujo, PhD, Martin S. Tallman, MD, Stanley L. Schrier, MD, Raul C. Ribeiro, MD, Arnold Ganser, MD, Bob Lowenberg, MD PhD, Francesco Lo Coco, MD, Miguel A. Sanz, MD, Nancy Berliner, MD, Eduardo Magalhães Rego, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2702.
https://doi.org/10.1182/blood.V130.Suppl_1.2702.2702
Published: 2017
Journal Articles

Overexpression of KMT2E Is Associated with Higher Granulocytic Differentiation Rate in Response to ATRA-Based Treatment in Acute Promyelocytic Leukemia Cell Lines

Diego Antonio Pereira-Martins, Isabel Weinhäuser, Luciana Yamamoto Almeida, PhD, Virginia Mara De Deus Wagatsuma, PhD, Priscila S Scheucher, PhD, Antonio R. Lucena-Araujo, PhD, Eduardo Magalhães Rego, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2680.
https://doi.org/10.1182/blood.V130.Suppl_1.2680.2680
Published: 2017
Journal Articles

Stathmin 1 Is Highly Expressed in Acute Promyelocytic Leukemia and Microtubule Dynamics Is a Potential Target for ATRA-Resistant APL Cells

João Agostinho Machado-Neto, BSc, Juan Luiz Coelho-Silva, BSc, MSc, Antonio R. Lucena-Araujo, PhD, Priscila S Scheucher, PhD, Raul Antônio Morais Melo, MD PhD, Rosane Bittencourt, MD, Ricardo Pasquini, MD, Katia B B Pagnano, MD PhD, Evandro Maranhão Fagundes, MD, Maria de Lourdes Chauffaille, MD PhD, Carlos Chiattone, MD, Eduardo Magalhães Rego, MDPhD, Fabiola Traina, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2514.
https://doi.org/10.1182/blood.V130.Suppl_1.2514.2514
Published: 2017
Journal Articles

High Aurora Kinase and Low Dido Levels Characterizes a Sub-Group of Chronic Lymphocytic Leukemia with Chromosomal Gains and High White Blood Cell Counts: Potential Inter-Regulatory Role of E2F1 and Mir-17-92 Cluster

Felipe C Souza, Msc., Josiane L Schiavinato, PhD, Antonio R. Lucena-Araujo, PhD, Fabio M Oliveira, PhD, Amelia G Araújo, Dimas Tadeu Covas, MD, PhD, Carlos Martínez-A, PhD, Marco A Zago, MD PhD, Rodrigo A Panepucci, PhD
Journal: Blood
Blood (2016) 128 (22): 2029.
https://doi.org/10.1182/blood.V128.22.2029.2029
Published: 2016
Journal Articles

Nuclear SET Domain (NSD) Protein Lysine Methyltransferases (KMT) Family Members Expression in Acute Myeloid Leukemia

Virginia Mara De Deus Wagatsuma, PhD, Luisa C A Koury, MD, Silvia Elena Sánchez, MSc, Lorena Lobo Figueiredo Pontes, MD; PhD, Fernanda Borges da Silva, MSc, Adriana Ines Dore, Biologist, Ana Silvia Gouvêa de Lima, PhD, Antonio R. Lucena-Araujo, PhD, Luciana Yamamoto Almeida, PhD, Fabiola Traina, MD, PhD, Felipe Saldanha-Araújo, PhD, Fabio Pittella-Silva, PhD, Eduardo Magalhães Rego, MD, PhD
Journal: Blood
Blood (2016) 128 (22): 5097.
https://doi.org/10.1182/blood.V128.22.5097.5097
Published: 2016
Journal Articles

Early Hematopoietic Progenitors of Dkc1 Hypomorphic Mutant Mice Display Decreased Proliferation Rate and an Impaired Control of Serine/Arginine-Rich Splicing Factor 4 (Srsf4) Translation

Antonio R Lucena-Araujo, PhD, Bárbara A Santana-Lemos, PhD, Carol H Thome, PhD, Germano A Ferreira, PhD, Davide Ruggero, Prof, MD PhD, Vitor Marcel Faça, Prof, PhD, Eduardo M Rego, Prof, MD PhD
Journal: Blood
Blood (2014) 124 (21): 2937.
https://doi.org/10.1182/blood.V124.21.2937.2937
Published: 2014
Journal Articles

Prognostic Impact Of MLL5 transcript Levels On Outcome Of Patients With Acute Promyelocytic Leukemia Treated With All-Trans Retinoic Acid and Anthracycline-Based Chemotherapy: An International Consortium On Acute Promyelocytic Leukemia Study

Antonio R Lucena-Araujo, PhD, Haesook T. Kim, PhD, Rafael Jacomo, MD, PhD, Raul A Melo, PhD, Rosane Bittencourt, MD, Ricardo Pasquini, MD, PhD, Katia B. Pagnano, MD, PhD, Evandro Fagundes, MD, Maria de Lourdes L. F. Chauffaille, MD, PhD, Ana S Lima, PhD, Hau C. Kwaan, M.D, F.R.C.P., Robert E Gallagher, MD, Charlotte M. Niemeyer, MD, Stanley L. Schrier, MD, Martin S Tallman, MD, David Grimwade, MD, PhD, Arnold Ganser, Nancy Berliner, MD, Raul Ribeiro, MD, Francesco Lo-Coco, MD, Bob Löwenberg, MD, PhD, Miguel Sanz, Eduardo M. Rego, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2586.
https://doi.org/10.1182/blood.V122.21.2586.2586
Published: 2013
Journal Articles

Aberrant Expression of the MLL5 , BAALC , ID1 , and WT1 Genes Is Associated with Higher Induction Mortality and Poorer Overall Survival in Acute Promyelocytic Leukemia Patients Treated with ATRA and Anthracycline-Based Chemotherapy: An International Consortium On Acute Promyelocytic Leukemia Study

Antonio R Lucena-Araujo, PhD, Rafael Henriques Jacomo, Haesook T Kim, PhD, Raul A Melo, Rosane Bittencourt, MD, Ricardo Pasquini, Katia B. Pagnano, MD, Evandro Fagundes, Maria de Lourdes L. F. Chauffaille, MD, PhD, Carlos S Chiattone, MD, PhD, Hau C. Kwaan, M.D., Ph.D., Robert E. Gallagher, MD, Charlotte M Niemeyer, Stanley L. Schrier, MD, Martin S Tallman, MD, David Grimwade, PhD, Arnold Ganser, Nancy Berliner, MD, Raul Ribeiro, MD, Roberto P. Falcao, M.D., Ph.D, Francesco Lo-Coco, MD, Bob Löwenberg, MD, PhD, Miguel Angel Sanz, Eduardo M Rego, MD
Journal: Blood
Blood (2012) 120 (21): 1407.
https://doi.org/10.1182/blood.V120.21.1407.1407
Published: 2012