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Antonio Costanzo
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Journal Articles

Pan-Aurora Kinase Inhibitor Mk-0457 Synergistically Potentiates Apo2L/Trail Cytotoxicity in Multiple Mieloma Cells Sensitive and Resistant to Bortezomib.

Paolo Lunghi, Laura Mazzera, Antonio Costanzo, Nicola Giuliani, Vittorio Rizzoli, Massimo Levrero, Antonio Bonati
Journal: Blood
Blood (2009) 114 (22): 1837.
https://doi.org/10.1182/blood.V114.22.1837.1837
Published: 2009
Journal Articles

Combined Treatment with the Mek Inhibitor PD0325901 and Arsenic Trioxide Has Potent Antitumor Activity in Vivo against Human Multiple Myeloma Xenograft Model.

Paolo Lunghi, Laura Mazzera, Guerino Lombardi, Micaela Ricca, Attilio Corradi, Anna Maria Cantoni, Nicola Giuliani, Luigi Salvatore, Roberta Riccioni, Antonio Costanzo, Ugo Testa, Massimo Levrero, Vittorio Rizzoli, Antonio Bonati
Journal: Blood
Blood (2008) 112 (11): 1712.
https://doi.org/10.1182/blood.V112.11.1712.1712
Published: 2008
Journal Articles

Targeting MEK/MAPK signal transduction module potentiates ATO-induced apoptosis in multiple myeloma cells through multiple signaling pathways

Paolo Lunghi, Nicola Giuliani, Laura Mazzera, Guerino Lombardi, Micaela Ricca, Attilio Corradi, Anna Maria Cantoni, Luigi Salvatore, Roberta Riccioni, Antonio Costanzo, Ugo Testa, Massimo Levrero, Vittorio Rizzoli, Antonio Bonati
Journal: Blood
Blood (2008) 112 (6): 2450–2462.
https://doi.org/10.1182/blood-2007-10-114348
Published: 2008
Includes: Supplemental data
Journal Articles

MEK1 inhibition sensitizes primary acute myelogenous leukemia to arsenic trioxide–induced apoptosis

Paolo Lunghi, Antonio Costanzo, Luigi Salvatore, Nelida Noguera, Laura Mazzera, Antonio Tabilio, Francesco Lo-Coco, Massimo Levrero, Antonio Bonati
Journal: Blood
Blood (2006) 107 (11): 4549–4553.
https://doi.org/10.1182/blood-2005-07-2829
Published: 2006
Journal Articles

Arsenic Trioxide (ATO) and MEK1 Inhibitor Activate Apoptotic p73 Pathway in Primary Acute Myelogenous Leukemia Blasts.

Paolo Lunghi, PhD, Antonio Costanzo, MD, Luigi Salvatore, PhD, Nelida Noguera, PhD, Antonio Tabilio, MD, Francesco Lo Coco, MD, Massimo Levrero, MD, Antonio Bonati, MD
Journal: Blood
Blood (2005) 106 (11): 613.
https://doi.org/10.1182/blood.V106.11.613.613
Published: 2005
Journal Articles

Treatment with arsenic trioxide (ATO) and MEK1 inhibitor activates the p73-p53AIP1 apoptotic pathway in leukemia cells

Paolo Lunghi, Antonio Costanzo, Massimo Levrero, Antonio Bonati
Journal: Blood
Blood (2004) 104 (2): 519–525.
https://doi.org/10.1182/blood-2003-08-2743
Published: 2004