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Journal Articles

The Immunophilin FKBP12 Inhibits Hepcidin By Modulating BMP Type I-Type II Receptors Interaction and Ligand Responsiveness

Alessandro Dulja, MSc, Alessia Pagani, PhD, Mariateresa Pettinato, Antonella Nai, PhD, Clara Camaschella, MD, Laura Silvestri, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 430.
https://doi.org/10.1182/blood-2019-130058
Published: 2019
Journal Articles

Targeting the BMP Receptor Inhibitor FKBP12 to Upregulate Hepcidin in Wild-Type and Hemojuvelin-Hemochromatosis Models

Mariateresa Pettinato, Mariam Aghajan, PhD, Violante Olivari, MSc, Alessandro Dulja, MSc, Antonella Nai, PhD, Jessica Bordini, PhD, Alessandro Campanella, PhD, Alessia Pagani, PhD, Shuling Guo, PhD, Clara Camaschella, MD, Laura Silvestri, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 955.
https://doi.org/10.1182/blood-2019-126496
Published: 2019
Journal Articles

Targeting Transferrin Receptor 2: A Novel "Erythropoiesis-Stimulating Approach" in a Model of Anemia of Chronic Kidney Disease

Violante Olivari, MSc, Maria Rosa Lidonnici, PhD, Mariateresa Pettinato, Laura Silvestri, PhD, Giuliana Ferrari, PhD, Clara Camaschella, MD, Antonella Nai, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 956.
https://doi.org/10.1182/blood-2019-125783
Published: 2019
Journal Articles

Novel Insights Into Systemic Iron Regulation

Laura Silvestri, PhD, Alessia Pagani, PhD, Antonella Nai, PhD, Clara Camaschella, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): SCI-1.
https://doi.org/10.1182/blood-2018-99-109518
Published: 2018
Journal Articles

Exploring the Mechanisms of Thalassemic Erythropoiesis Improvement Caused By Bone Marrow Tfr2 Deletion

Antonella Nai, PhD, Irene Artuso, MSc, Maria Rosa Lidonnici, PhD, Sandro Altamura, PhD, Giacomo Mandelli, PhD, Mariateresa Pettinato, MSc, Martina U. Muckenthaler, PhD, Laura Silvestri, PhD, Giuliana Ferrari, PhD, Clara Camaschella, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3624.
https://doi.org/10.1182/blood-2018-99-115835
Published: 2018
Journal Articles

Inhibiting the Immunophilin FKBP12: A Potential Therapeutic Approach to Iron Overload/Low Hepcidin Disorders

Mariateresa Pettinato, MSc, Mariam Aghajan, Alessandro Dulja, Antonella Nai, PhD, Violante Olivari, Jessica Bordini, MSc, Alessandro Campanella, PhD, Alessia Pagani, PhD, Shuling Guo, Clara Camaschella, MD, Laura Silvestri, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2333.
https://doi.org/10.1182/blood-2018-99-118112
Published: 2018
Journal Articles

NCOA4 Links Iron Bioavailability to DNA Metabolism

Giorgia Federico, PhD, Roberto Bellelli, PhD, Antonella Nai, PhD, Laura Silvestri, PhD, Clara Camaschella, MD, Achille Iolascon, MD PhD, Massimo Santoro, MD, Francesca Carlomagno, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 223.
https://doi.org/10.1182/blood.V130.Suppl_1.223.223
Published: 2017
Journal Articles

The Macrophage Nuclear Receptor Coactivator 4 Counteracts Iron-Deficiency Anemia

Antonella Nai, PhD, Maria Rosa Lidonnici, Irene Artuso, MSc, Giorgia Federico, PhD, Giacomo Mandelli, Giuliana Ferrari, PhD, Clara Camaschella, MD, Francesca Carlomagno, MD, Laura Silvestri, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 224.
https://doi.org/10.1182/blood.V130.Suppl_1.224.224
Published: 2017
Journal Articles

Transient Reduction of Transferrin Saturation Contributes to Hepcidin Inhibition Independently of Erfe in Mice Treated with Erythropoietin

Irene Artuso, MSc, Antonella Nai, PhD, Mariateresa Pettinato, MSc, Alessia Pagani, PhD, Chloe Latour, Benjamin Billore, Maria Rosa Lidonnici, Giacomo Mandelli, Giuliana Ferrari, Clara Camaschella, MD, Leon C. Kautz, PhD, Laura Silvestri, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 174.
https://doi.org/10.1182/blood.V130.Suppl_1.174.174
Published: 2017
Journal Articles

A Novel Crosstalk Between Iron Homeostasis and mTOR Mediated By the Immunophilin FKBP12

Laura Silvestri, PhD, Silvia Colucci, Alessia Pagani, PhD, Irene Artuso, BSc, Mariatesera Pettinato, BSc, Antonella Nai, PhD, Clara Camaschella, MD
Journal: Blood
Blood (2016) 128 (22): 261.
https://doi.org/10.1182/blood.V128.22.261.261
Published: 2016
Journal Articles

Unraveling the Erythroid Function of Tfr2 in Beta-Thalassemia

Antonella Nai, PhD, Maria Rosa Lidonnici, PhD, Irene Artuso, BSc, Giacomo Mandelli, PhD, Mariateresa Pettinato, BSc, Laura Silvestri, PhD, Giuliana Ferrari, PhD, Clara Camaschella, MD
Journal: Blood
Blood (2016) 128 (22): 73.
https://doi.org/10.1182/blood.V128.22.73.73
Published: 2016
Journal Articles

Inactivation of Tmprss6 Hampers Hepcidin Inhibition By Erythroferrone through Upregulation of the BMP-SMAD Pathway

Laura Silvestri, PhD, Antonella Nai, PhD, Alessandro Campanella, PhD, Irene Artuso, BSc, Jessica Bordini, BSc, Clara Camaschella, MD
Journal: Blood
Blood (2015) 126 (23): 408.
https://doi.org/10.1182/blood.V126.23.408.408
Published: 2015
Journal Articles

Is Tmprss6 Required for Hepcidin Inhibition By Erythroferrone?

Laura Silvestri, PhD, Grazia Rita Gelsomino, Antonella Nai, PhD, Marco Rausa, Alessia Pagani, PhD, Clara Camaschella, MD
Journal: Blood
Blood (2014) 124 (21): 1347.
https://doi.org/10.1182/blood.V124.21.1347.1347
Published: 2014
Journal Articles

The Role Of Liver Endothelial Sinusoidal Cells In Iron-Mediated Bmp6 Regulation

Laura Silvestri, PhD, Marco Rausa, Antonella Nai, PhD, Alessia Pagani, PhD, Clara Camaschella, MD
Journal: Blood
Blood (2013) 122 (21): 177.
https://doi.org/10.1182/blood.V122.21.177.177
Published: 2013