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Antoine Soubret, PhD
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Journal Articles

An Optimized Crovalimab Dose and Regimen Reduced the Formation of Drug-Target-Drug Complexes in Patients with Paroxysmal Nocturnal Hemoglobinuria from the Phase I/II COMPOSER Trial

Jun-ichi Nishimura, MD PhD, Antoine Soubret, PhD, Simon Buatois, PharmD, PhD, Jean-Eric Charoin, Sasha Sreckovic, MD, Christoph Bucher, Jules Hernández-Sánchez, PhD, Gregor Jordan, Julia Ramos, MD PhD, Noriko Arase, MD PhD, Masaki Hotta, Yoshitaka Isaka, Yoshikazu Ito, MD PhD, Yuzuru Kanakura, MD PhD, Jin Seok Kim, MD PhD, Taroh Kinoshita, PhD, Eiichi Morii, Jens Panse, MD, Regis Peffault De Latour, MD PhD, Alexander Röth, MD, Hubert Schrezenmeier, Simona Sica, MD PhD, Hiroyuki Takamori, MD, Yasutaka Ueda, Sung-Soo Yoon, MD PhD, Ido Paz-Priel, Alexandre Sostelly, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 2–3.
https://doi.org/10.1182/blood-2020-136265
Published: 2020
Journal Articles

Population Pharmacokinetic/Pharmacodynamic Modelling from the Phase I/II COMPOSER Trial to Predict Lowering of Lactate Dehydrogenase in Crovalimab-Treated Patients with Paroxysmal Nocturnal Hemoglobinuria

Simon Buatois, PharmD, PhD, Alexandre Sostelly, PhD, Antoine Soubret, PhD, Felix Jaminion, Valerie Cosson, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 9–10.
https://doi.org/10.1182/blood-2020-134590
Published: 2020
Journal Articles

COMPOSER Part 4: An Optimized Dosing Strategy for Crovalimab in the Treatment of Complement Inhibitor-Naïve or -Experienced Patients with Paroxysmal Nocturnal Hemoglobinuria

Regis Peffault De Latour, MD PhD, Simona Sica, MD PhD, Julia Ramos, MD, Jules Hernández-Sánchez, PhD, Jin Seok Kim, MD PhD, Anna Kiialainen, PhD, Sung-Soo Yoon, MD PhD, Sasha Sreckovic, MD, Antoine Soubret, PhD, Haruhiko Ninomiya, MD PhD, Alexandre Sostelly, PhD, Jens Panse, MD, Simon Buatois, PharmD, PhD, Hubert Schrezenmeier, Ido Paz-Priel, MD, Jun-ichi Nishimura, MD PhD, Alexander Röth, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 6–7.
https://doi.org/10.1182/blood-2020-135841
Published: 2020