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Journal Articles

Dasatinib Has a Dual Mode of Action: Direct BCR-ABL1 Mediated Anti-Leukemic Effects Are Complemented by Promotion of Th1-Type and NK-Cell Mediated Cellular Immune Responses,

Anna Kreutzman, MSc, Jukka Vakkila, MD, PhD, Kimmo Porkka, MD, PhD, Satu Mustjoki, MD, PhD

Blood (2011) 118 (21): 3760.

https://doi.org/10.1182/blood.V118.21.3760.3760

Published: 2011

Journal Articles

Interferon Alpha Treated Patients with Chronic Myeloid Leukemia (CML) In Prolonged Complete Remission Have Increased Numbers of NK-Cells and Clonal Gamma-Delta T-Cells, and a Distinct Plasma Cytokine Profile.

Anna Kreutzman, MSc, Peter Rohon, MD, Edgar Faber, MD, PhD, Karel Indrak, MD, PhD, Vesa Juvonen, PhD, Veli Kairisto, MD, PhD, Jaroslava Voglova, MD, Marjatta Sinisalo, MD, PhD, Emilia Flochova, MD, PhD, Petteri Arstila, MD, PhD, Kimmo Porkka, MD, PhD, Satu Mustjoki, MD, PhD

Blood (2010) 116 (21): 1201.

https://doi.org/10.1182/blood.V116.21.1201.1201

Published: 2010

Journal Articles

Dasatinib Induces a Rapid, Dose-Controllable Mobilization of Cytotoxic Lymphocytes: A Novel Immunomodulatory Effect Associated with Prolonged Therapy Responses In Advanced Leukemia.

Satu Mustjoki, MD, PhD, Philippe Rousselot, MD, PhD, Sari Jalkanen, Msc, Anna Kreutzman, MSc, Teresa Melo, MD, Anna-Maria Lahesmaa, MSc, Sampsa Hautaniemi, PhD, Mathieu Molimard, MD, PhD, Richard Smykla, PhD, Francis Lee, PhD, Jukka Vakkila, MD, PhD, Kimmo Porkka, MD, PhD

Blood (2010) 116 (21): 1204.

https://doi.org/10.1182/blood.V116.21.1204.1204

Published: 2010

Journal Articles

Mono/Oligoclonal T and NK Cells Are Common in Philadelphia Chromosome Positive (Ph+) Leukemia Patients at Diagnosis and Expand During Successful Tyrosine Kinase Inhibitor Therapy.

Anna Kreutzman, MSc, Vesa Juvonen, PhD, Veli Kairisto, MD, PhD, Marja Ekblom, MD, PhD, Leif Stenke, MD, PhD, Ruth Seggewiss, MD, Kimmo Porkka, MD, PhD, Satu Mustjoki, MD, PhD

Blood (2009) 114 (22): 856.

https://doi.org/10.1182/blood.V114.22.856.856

Published: 2009

Journal Articles

Large Granular Lymphocyte (LGL) Expansions Comprising Oligoclonal T Cell or NK Cell Populations in Dasatinib Treated Patients Are Associated with HLA-A*0201, CMV Reactivation and Enhanced Anti-Leukemic Control.

Satu Mustjoki, MD, PhD, Anna Kreutzman, MSc, Carolin Dix, David A Price, MRCP, DPhil, Kristin Ladell, MD, Marja Ekblom, MD, PhD, Leif Stenke, MD, PhD, Hermann Einsele, MD, Kimmo Porkka, MD, PhD, Ruth Seggewiss, MD

Blood (2009) 114 (22): 1123.

https://doi.org/10.1182/blood.V114.22.1123.1123

Published: 2009

Journal Articles

Clonal Expansion of T/NK-Cells during Tyrosine Kinase Inhibitor Dasatinib Therapy

Blood (2008) 112 (11): 573.

https://doi.org/10.1182/blood.V112.11.573.573

Published: 2008

NARROW

Dasatinib Has a Dual Mode of Action: Direct BCR-ABL1 Mediated Anti-Leukemic Effects Are Complemented by Promotion of Th1-Type and NK-Cell Mediated Cellular Immune Responses,

Interferon Alpha Treated Patients with Chronic Myeloid Leukemia (CML) In Prolonged Complete Remission Have Increased Numbers of NK-Cells and Clonal Gamma-Delta T-Cells, and a Distinct Plasma Cytokine Profile.

Dasatinib Induces a Rapid, Dose-Controllable Mobilization of Cytotoxic Lymphocytes: A Novel Immunomodulatory Effect Associated with Prolonged Therapy Responses In Advanced Leukemia.

Mono/Oligoclonal T and NK Cells Are Common in Philadelphia Chromosome Positive (Ph+) Leukemia Patients at Diagnosis and Expand During Successful Tyrosine Kinase Inhibitor Therapy.

Large Granular Lymphocyte (LGL) Expansions Comprising Oligoclonal T Cell or NK Cell Populations in Dasatinib Treated Patients Are Associated with HLA-A*0201, CMV Reactivation and Enhanced Anti-Leukemic Control.

Clonal Expansion of T/NK-Cells during Tyrosine Kinase Inhibitor Dasatinib Therapy

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ASH Publications

American Society of Hematology

Dasatinib Has a Dual Mode of Action: Direct BCR-ABL1 Mediated Anti-Leukemic Effects Are Complemented by Promotion of Th1-Type and NK-Cell Mediated Cellular Immune Responses,

Interferon Alpha Treated Patients with Chronic Myeloid Leukemia (CML) In Prolonged Complete Remission Have Increased Numbers of NK-Cells and Clonal Gamma-Delta T-Cells, and a Distinct Plasma Cytokine Profile.

Dasatinib Induces a Rapid, Dose-Controllable Mobilization of Cytotoxic Lymphocytes: A Novel Immunomodulatory Effect Associated with Prolonged Therapy Responses In Advanced Leukemia.

Mono/Oligoclonal T and NK Cells Are Common in Philadelphia Chromosome Positive (Ph+) Leukemia Patients at Diagnosis and Expand During Successful Tyrosine Kinase Inhibitor Therapy.

Large Granular Lymphocyte (LGL) Expansions Comprising Oligoclonal T Cell or NK Cell Populations in Dasatinib Treated Patients Are Associated with HLA-A*0201, CMV Reactivation and Enhanced Anti-Leukemic Control.

Clonal Expansion of T/NK-Cells during Tyrosine Kinase Inhibitor Dasatinib Therapy

Email alerts

ASH Publications

American Society of Hematology

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