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Andrew Crew
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Journal Articles

Preclinical Activity of Novel BET Protein Proteolysis Targeting Chimeras (BETP-PROTACs) and Their Combination with Venetoclax or CDK4/6 Inhibitor Against Human Mantle Cell Lymphoma (MCL) Cells

Baohua Sun, MD PhD, Warren Fiskus, BSc,PhD, Kanak Raina, PhD, Yimin Qian, PhD, Andrew Crew, Dyana T. Saenz, PhD, Christopher Peter Mill, PhD BA, Agnieszka J Nowak, David N Saenz, Craig M Crews, PhD, Kapil N. Bhalla, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1265.
https://doi.org/10.1182/blood.V130.Suppl_1.1265.1265
Published: 2017
Journal Articles

Novel BET Protein Proteolysis Targeting Chimeras (BETP-PROTACs) Exert Potent Single Agent and Synergistic Activity with Ibrutinib and Venetoclax Against Human Mantle Cell Lymphoma Cells

Baohua Sun, MD PhD, Warren Fiskus, PhD, Liang Zhang, MD PhD, Kanak Raina, PhD, Kevin Coleman, PhD, Jim Winkler, PhD, Yimin Qian, PhD, Andrew Crew, PhD, Angela Shen, MD, Dyana T Saenz, PhD, Christopher P Mill, PhD, Michael Wang, MD, Craig Crews, PhD, Kapil N. Bhalla, MD
Journal: Blood
Blood (2016) 128 (22): 1058.
https://doi.org/10.1182/blood.V128.22.1058.1058
Published: 2016
Journal Articles

Superior Lethal Activity of Novel BET Protein Proteolysis Targeting Chimera (BETP-PROTACs) Versus Betp Bromodomain Inhibitor (BETi) Against Post-Myeloproliferative Neoplasm (MPN) Secondary (s) AML Cells

Dyana T Saenz, PhD, Warren Fiskus, PhD, Kanak Raina, PhD, Taghi Manshouri, PhD, Kevin Coleman, PhD, Jim Winkler, PhD, Yimin Qian, PhD, Andrew Crew, PhD, Angela Shen, MD, Christopher P Mill, PhD, Baohua Sun, MD PhD, Srdan Verstovsek, MD PhD, Craig Crews, PhD, Kapil N. Bhalla, MD
Journal: Blood
Blood (2016) 128 (22): 747.
https://doi.org/10.1182/blood.V128.22.747.747
Published: 2016
Journal Articles

BRD4 Degradation By Protacs Represents a More Effective Therapeutic Strategy Than BRD4 Inhibitors in DLBCL

Jing Lu, PhD, Yimin Qian, PhD, Kanak Raina, PhD, Martha Altieri, MS, Hanqing Dong, PhD, Jing Wang, PhD, Xin Chen, PhD, Andrew Crew, PhD, Kevin Coleman, PhD, Craig Crews, PhD, James Winkler, PhD
Journal: Blood
Blood (2015) 126 (23): 2050.
https://doi.org/10.1182/blood.V126.23.2050.2050
Published: 2015