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Journal Articles

Deletion of the Artery Specific Enhancer Promotes B Cell and Impairs T Cell Development from the Hemogenic Endothelium

Saritha S. D'souza, Akhilesh Kumar, Yoon Jung Choi, Samuel Dettle, Isla Emmen, Portia Smith, Divine M. Sedzro, Ho Sun Jung, Peng Liu, Igor Slukvin
Journal: Blood
Blood (2023) 142 (Supplement 1): 1299.
https://doi.org/10.1182/blood-2023-174748
Published: 2023
Journal Articles

BCL11B Modulates Hemogenic Endothelium-Derived Multipotent Hematopoietic Progenitors and Enhances Myeloid and Lymphoid Pathways from Human iPSCs

Akhilesh Kumar, Colin Fischer, Alexander Lenvik, Ojas Singh, Jeffrey S Miller, Frank Cichocki
Journal: Blood
Blood (2023) 142 (Supplement 1): 2684.
https://doi.org/10.1182/blood-2023-188760
Published: 2023
Journal Articles

Artery Specific Enhancer Is Essential for Specification of Arterial Hemogenic Endothelium with T Lymphoid Potential

Saritha S D'souza, Akhilesh Kumar, Yoon Jung Choi, Samuel T Dettle, Portia Smith, Ho Sun Jung, Peng Liu, Irene Ong, Igor I Slukvin
Journal: Blood
Blood (2022) 140 (Supplement 1): 8592–8593.
https://doi.org/10.1182/blood-2022-168131
Published: 2022
Journal Articles

Infusion of iPSC-Derived CD34 + Hematopoietic Progenitors Following Myeloablative HSC Transplantation and Assessment of Their Immunogenicity in MHC-Defined Nonhuman Primate Model

Saritha S D'souza, Akhilesh Kumar, John P Maufort, Nick Strelchenko, Mathew Raymond, Jason Weinfurter, Jennifer Coonen, Matt Reynolds, James A. Thomson, Igor I Slukvin
Journal: Blood
Blood (2021) 138 (Supplement 1): 2763.
https://doi.org/10.1182/blood-2021-149003
Published: 2021
Journal Articles

NOTCH Activation at the Definitive Mesoderm Stage Facilitates Efficient Generation of T Cells with High Proliferation Potential from Human Pluripotent Stem Cells

Akhilesh Kumar, PhD, Kran Suknuntha, MDPhD, Saritha S D'souza, PhD, Jeong Hee Lee, MS, Andres Grandea, PhD, Abhir S Thakur, David T Evans, PhD, Igor Slukvin, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3185.
https://doi.org/10.1182/blood.V130.Suppl_1.3185.3185
Published: 2017
Journal Articles

Induction of Arterial Type of Hemogenic Endothelium from Human Pluripotent Stem Cells

Mi Ae Park, PhD, Akhilesh Kumar, PhD, Ho Sun Jung, PhD, Gene Ueneshi, PhD, Oleg Moskvin, PhD, Scott Swanson, PhD, James A. Thomson, VMD, PhD, Igor Slukvin, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1143.
https://doi.org/10.1182/blood.V130.Suppl_1.1143.1143
Published: 2017
Journal Articles

Efficient Induction of Myleoid and Lymphoid Hematopoiesis from Nonhuman Primate Pluripotent Stem Cells Using GSK3b Inhibitor

Saritha D'Souza, PhD, John Maufort, PhD, Akhilesh Kumar, PhD, James Thomson, D.V.M., PhD, Igor Slukvin, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2363.
https://doi.org/10.1182/blood.V126.23.2363.2363
Published: 2015