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Journal Articles

Novel Evidence That the Nlrp3 Inflammasome Plays a Role in Bone Marrow As a "Cogwheel" Connecting Purinergic Signaling with Activation of the Complement Cascade to Induce "Sterile Inflammation", Which Is Required for Optimal Mobilization of Hematopoietic Stem/Progenitor Cells

Mateusz Adamiak, PhD, Anna Lenkiewicz, PhD, Kamila Bujko, MS, Arjun Thapa, PhD, Magdalena Kucia, PhD DSci, Ahmed Abdel-Latif, MD PhD, Janina Ratajczak, MD PhD DSci, Mariusz Z Ratajczak, MD PhD DSc

Blood (2019) 134 (Supplement_1): 4468.

https://doi.org/10.1182/blood-2019-125838

Published: 2019

Journal Articles

Sphingosine Kinase 2 (SphK2) Deficiency Does Not Lower but Instead Surprisingly Increases the Level of Sphingosine-1-Phosphate (S1P) in Peripheral Blood, Providing a Novel Strategy for Stimulating Hematopoietic Stem Cell Mobilization By Inhibiting SphK2 Activity

Mateusz Adamiak, PhD, Lakshman Chelvarajan, Webster Santos, PhD, Kevin R Lynch, PhD, Ahmed Abdel-Latif, MD PhD, Mariusz Z Ratajczak, MD PhD DSc

Blood (2017) 130 (Supplement 1): 4477.

https://doi.org/10.1182/blood.V130.Suppl_1.4477.4477

Published: 2017

Journal Articles

Novel Evidence That the Mannan-Binding Lectin (MBL) Pathway of Complement Activation Plays a Pivotal Role in Triggering Mobilization of Hematopoietic Stem/Progenitor Cells By Activation of Both the Complement and Coagulation Cascades

Mateusz Adamiak, Malwina Suszynska, PhD, Ahmed Abdel-Latif, MD PhD, Ahmed Abdelbaset-Ismail, PhD, Janina Ratajczak, MD PhD, Magdalena Kucia, PhD, Mariusz Z Ratajczak, MD PhD

Blood (2016) 128 (22): 3371.

https://doi.org/10.1182/blood.V128.22.3371.3371

Published: 2016

Journal Articles

Unexpected Evidence That Inducible Nitric Oxide Synthase (iNOS) Is a Negative Regulator of Hematopoietic Stem/Progenitor Cell Mobilization

Mateusz Adamiak, MS, Ahmed Abdelbaset-Ismail, PhD, Marcin Wysoczynski, PhD, Ahmed Abdel-Latif, MD PhD, Joseph B Moore, IV, MS, Janina Ratajczak, MD PhD, Mariusz Z Ratajczak, MD PhD

Blood (2016) 128 (22): 3372.

https://doi.org/10.1182/blood.V128.22.3372.3372

Published: 2016

Journal Articles

Novel Evidence That Hematopoietic-Specific PLC-β2 Is Required for Normal Homing and Engraftment of Hematopoietic Stem Cells

Mateusz Adamiak, MS, Ahmed Abdelbaset Ismail, PhD, Ahmed Abdel-Latif, MD PhD, Janina Ratajczak, MD PhD, Magdalena Kucia, PhD, Mariusz Z Ratajczak, MD PhD

Blood (2016) 128 (22): 3342.

https://doi.org/10.1182/blood.V128.22.3342.3342

Published: 2016

Journal Articles

Heme Oxygenase 1 (HO-1) Is a Novel Negative Regulator of Normal and Malignant Hematopoietic Cell Trafficking

Mateusz Adamiak, MS, Ahmed Abdelbaset-Ismail, PhD, Joseph B Moore, IV, MS, Ahmed Abdel-Latif, MD PhD, Marcin Wysoczynski, PhD, Magdalena Kucia, PhD, Janina Ratajczak, MD PhD, Mariusz Z Ratajczak, MD PhD

Blood (2016) 128 (22): 2150.

https://doi.org/10.1182/blood.V128.22.2150.2150

Published: 2016

Journal Articles

A Novel and Pivotal Role of the Mannose-Binding Lectin (MBL) Pathway of Complement Cascade (ComC) Activation in Triggering Mobilization of Hematopoietic Stem/Progenitor Cells (HSPCs)

Mateusz Adamiak, MS, Ahmed Abdel-Latif, MD PhD, Janina Ratajczak, MD PhD, Mariusz Z Ratajczak, MD PhD

Blood (2015) 126 (23): 4301.

https://doi.org/10.1182/blood.V126.23.4301.4301

Published: 2015

Journal Articles

Novel Evidence That a Lipolytic Enzyme - Hematopoietic-Specific Phospholipase C Beta 2 - Promotes Mobilization of Hematopoietic Stem Cells By Decreasing Their Lipid Raft-Mediated Bone Marrow Retention and Increasing the Pro-Mobilizing Effects of Granulocytes

Mateusz Adamiak, MS, Agata Poniewierska-Baran, PhD, Gabriela Schneider, PhD, Ahmed Abdelbaset-Ismail, PhD, Malwina Suszynska, PhD, Ahmed Abdel-Latif, MD PhD, Magdalena Kucia, PhD, Janina Ratajczak, MD PhD, Mariusz Z Ratajczak, MD PhD

Blood (2015) 126 (23): 1896.

https://doi.org/10.1182/blood.V126.23.1896.1896

Published: 2015

Journal Articles

Novel Evidence That Sphingosine-1-Phosphate-Mediated Mobilization Of Hematopoietic Stem/Progenitor Cells (HSPCs) During Intravascular Hemolysis Requires Attenuation Of The SDF-1–CXCR4 Retention Axis Of HSPCs In Bone Marrow Niches – Implications For Paroxysmal Nocturnal Hemoglobinuria-Induced Mobilization of HSPCs

Kasia Mierzejewska, PhD, Ahmed Abdel-Latif, MD, Gabriela Schneider, Ph.D., Janina Ratajczak, MD, PhD, Magdalena Kucia, Ph.D., Mariusz Z Ratajczak, MD, PhD

Blood (2013) 122 (21): 2477.

https://doi.org/10.1182/blood.V122.21.2477.2477

Published: 2013

Journal Articles

A Novel Perspective On Hematopoietic Stem/Progenitor Cell Homing - an Expanding Family of Bone Marrow Homing Factors That Can Support SDF-1-Mediated Homing or Even Replace SDF-1

Gabriela Schneider, Ph.D., Kim ChiHwa, PhD, Ahmed Abdel-Latif, MD, Anna Janowska-Wieczorek, MD, PhD, Janina Ratajczak, MD, PhD, Mariusz Z Ratajczak, MD, PhD

Blood (2012) 120 (21): 1247.

https://doi.org/10.1182/blood.V120.21.1247.1247

Published: 2012

Journal Articles

Novel Role for Bioactive Lipids in Mobilization of Bone Marrow Stem Cells During Myocardial Ischemia: Sphingosine-1 Phosphate (S1P) As Potential Therapeutic Target

Ahmed Abdel Latif, MD, Anush K. Karapetyan, PhD, Yuri Klyachkin, PhD, Manjula Sunkara, MS, Susan Smyth, MD, PhD, Mariusz Z Ratajczak, MD, PhD, Andrew J. Morris, PhD

Blood (2012) 120 (21): 1911.

https://doi.org/10.1182/blood.V120.21.1911.1911

Published: 2012

Journal Articles

Differential Responsiveness of HSPCs Harvested From Bone Marrow (BM), Mobilized Peripheral Blood (mPB) and Umbilical Cord Blood (UCB) to the BM Homing Factors Stromal-Derived Factor-1 (SDF-1), Sphingosine-1 Phosphate (S1P) and Ceramide-1 Phosphate (C1P) Is Related to the Desensitization of mPB and UCB HSPCs by S1P and C1P Present in mPB and UCB Plasma

Ahmed Abdel-Latif, MD, Anush V Karapetyan, PhD, Chihwa Kim, PhD, Mariusz Z Ratajczak, MD, PhD, DSc

Blood (2011) 118 (21): 2958.

https://doi.org/10.1182/blood.V118.21.2958.2958

Published: 2011

Journal Articles

Evidence That a Bioactive Lipid, Ceramide-1 Phosphate (C1P), Is Upregulated In Bone Marrow Microenvironment After Myeloablative Therapy and Is a Potential Novel Homing Factor for Hematopoietic Stem Cells

Chihwa Kim, Ph.D, Wu Wan, MS, Ahmed Abdel-Latif, MD, Marcin Wysoczynski, PhD, Magdalena Kucia, PhD, Janina Ratajczak, MD, PhD, Mariusz Z Ratajczak, MD, PhD, DSc

Blood (2010) 116 (21): 401.

https://doi.org/10.1182/blood.V116.21.401.401

Published: 2010

NARROW

Novel Evidence That the Nlrp3 Inflammasome Plays a Role in Bone Marrow As a "Cogwheel" Connecting Purinergic Signaling with Activation of the Complement Cascade to Induce "Sterile Inflammation", Which Is Required for Optimal Mobilization of Hematopoietic Stem/Progenitor Cells

Sphingosine Kinase 2 (SphK2) Deficiency Does Not Lower but Instead Surprisingly Increases the Level of Sphingosine-1-Phosphate (S1P) in Peripheral Blood, Providing a Novel Strategy for Stimulating Hematopoietic Stem Cell Mobilization By Inhibiting SphK2 Activity

Novel Evidence That the Mannan-Binding Lectin (MBL) Pathway of Complement Activation Plays a Pivotal Role in Triggering Mobilization of Hematopoietic Stem/Progenitor Cells By Activation of Both the Complement and Coagulation Cascades

Unexpected Evidence That Inducible Nitric Oxide Synthase (iNOS) Is a Negative Regulator of Hematopoietic Stem/Progenitor Cell Mobilization

Novel Evidence That Hematopoietic-Specific PLC-β2 Is Required for Normal Homing and Engraftment of Hematopoietic Stem Cells

Heme Oxygenase 1 (HO-1) Is a Novel Negative Regulator of Normal and Malignant Hematopoietic Cell Trafficking

A Novel and Pivotal Role of the Mannose-Binding Lectin (MBL) Pathway of Complement Cascade (ComC) Activation in Triggering Mobilization of Hematopoietic Stem/Progenitor Cells (HSPCs)

Novel Evidence That a Lipolytic Enzyme - Hematopoietic-Specific Phospholipase C Beta 2 - Promotes Mobilization of Hematopoietic Stem Cells By Decreasing Their Lipid Raft-Mediated Bone Marrow Retention and Increasing the Pro-Mobilizing Effects of Granulocytes

A Novel Perspective On Hematopoietic Stem/Progenitor Cell Homing - an Expanding Family of Bone Marrow Homing Factors That Can Support SDF-1-Mediated Homing or Even Replace SDF-1

Novel Role for Bioactive Lipids in Mobilization of Bone Marrow Stem Cells During Myocardial Ischemia: Sphingosine-1 Phosphate (S1P) As Potential Therapeutic Target

Evidence That a Bioactive Lipid, Ceramide-1 Phosphate (C1P), Is Upregulated In Bone Marrow Microenvironment After Myeloablative Therapy and Is a Potential Novel Homing Factor for Hematopoietic Stem Cells

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American Society of Hematology

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ASH Publications

American Society of Hematology

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