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Aaron R Thorner, PhD
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Journal Articles

Genomic Profiling of a Phase III Clinical Trial of Interferon Versus Hydroxyurea in MPN Patients Reveals Mutation-Specific and Treatment-Specific Patterns of Response

Trine Alma Knudsen, MD, Vibe Skov, PhD, Lillian Werner, MS, William Duke, Christopher J. Gibson, MD, Anwesha Nag, PhD, Aaron R. Thorner, PhD, Bruce Wollison, MS, Dennis Lund Hansen, MD, Thomas Stauffer Larsen, MD PhD, Christina Ellervik, MD PhD, Daniel El Fassi, MD, Karin de Stricker, MD, Lukas Frans Ocias, MD, Mette Brabrand, Ole Weis Bjerrum, MD PhD, Ulrik Malthe Overgaard, MD, Mikael Frederiksen, MD, Thomas Kielsgaard Kristensen, Torben A Kruse, Mads Thomassen, PhD, Torben Mourits-Andersen, MD, Marianne Tang Severinsen, MD PhD, Jesper Stentoft, MD, Joern Starklint, Peter Møller, MD, Donna S Neuberg, ScD, Lasse Kjær, PhD, Hans Hasselbalch, MD, R. Coleman Lindsley, MD PhD, Ann Mullally, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4202.
https://doi.org/10.1182/blood-2019-126164
Published: 2019
Journal Articles

Comparative Genomic Analyses Defines Shared and Unique Features of cHL and PMBL and New Mechanisms of Sensitivity to PD-1 Blockade

Kirsty Wienand, PhD, Bjoern Chapuy, MD PhD, Chip Stewart, PhD, Andrew Dunford, MS, David Wu, MD PhD, Jaegil Kim, PhD, Atanas Kamburov, PhD, Timothy Wood, Fathima Zumla Cader, MD PhD MRCP, Matthew D. Ducar, MS, Aaron R. Thorner, PhD, Anwesha Nag, PhD, Gabriel K Griffin, MD, Pei-Hsuan Chen, Alexander T Heubeck, BS, Michael J Buonopane, BS, Kamil Bojarczuk, PhD, Claire McEwen Cote, Lee N. Lawton, PhD, Philippe Armand, MD PhD, Scott J Rodig, MD PhD, Jonathan R. Fromm, MD PhD, Gad Getz, PhD, Margaret A. Shipp, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1493.
https://doi.org/10.1182/blood-2019-131904
Published: 2019
Journal Articles

Recurrent Genetic HLA Loss in Acute Myeloid Leukemia Relapsed after Matched Unrelated Allogeneic Hematopoietic Cell Transplant

Max Jan, MD PhD, Matt J Leventhal, BA, Elizabeth A Morgan, MD, Jordan Chase Wengrod, MD PhD, Anewsha Nag, PhD, Samantha D Drinan, BS, Bruce M Wollison, MSc, Matthew D. Ducar, MS, Aaron R. Thorner, PhD, Natasha Kekre, MDFRCPC, Vincent T. Ho, MD, John Koreth, MBBS, DPhil, Corey S. Cutler, MD MPH, Sarah Nikiforow, MD PhD, Edwin P. Alyea, III, MD, Joseph H. Antin, MD, Robert J. Soiffer, MD, Jerome Ritz, MD PhD, R. Coleman Lindsley, MD, PhD, Benjamin L. Ebert, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 817.
https://doi.org/10.1182/blood-2018-99-113911
Published: 2018
Journal Articles

Comprehensive Genomic Analysis of Flow-Sorted Hodgkin Reed Sternberg Cells Reveals Additional Genetic Bases of Immune Evasion

Kirsty Wienand, PhD, Bjoern Chapuy, MDPhD, Chip Stewart, PhD, Andrew Dunford, MS, David Wu, MD PhD, Jaegil Kim, PhD, Atanas Kamburov, PhD, Fathima Zumla Cader, MD PhD MRCP, Matthew D. Ducar, MS, Aaron R. Thorner, PhD, Alexander T Heubeck, BS, Michael J Buonopane, BS, Philippe Armand, MD PhD, Scott J Rodig, MD, Jonathan R. Fromm, MD PhD, Gad Getz, PhD, Margaret A. Shipp, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1559.
https://doi.org/10.1182/blood-2018-99-118453
Published: 2018
Journal Articles

Comprehensive Genomic Analysis of Primary Mediastinal B-Cell Lymphoma

Bjoern Chapuy, MDPhD, Chip Stewart, PhD, Andrew Dunford, MS, Jaegil Kim, PhD, Kirsty Wienand, PhD, Atanas Kamburov, PhD, Gabriel Kenneth Griffin, MD, Claire McEwen Cote, Matthew D. Ducar, MS, Aaron R. Thorner, PhD, Scott J Rodig, MD, Gad Getz, PhD, Margaret A. Shipp, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1564.
https://doi.org/10.1182/blood-2018-99-118135
Published: 2018
Journal Articles

Hedgehog Pathway Mutations Drive Oncogenic Transformation in High-Risk T-Cell Acute Lymphoblastic Leukemia

Melissa A. Burns, MD, Zi Wei Liao, Gayle P. Pouliot, MD PhD, Kristen E. Stevenson, MS, Donna S. Neuberg, ScD, Aaron R. Thorner, PhD, Matthew D. Ducar, MS, Emily A. Silverman, Stephen P. Hunger, MD, Mignon L. Loh, MD, Stuart S. Winter, MD, Kimberly P. Dunsmore, MD, Brent Wood, MDPhD, Meenakshi Devidas, PhD, Marian H. Harris, MD PhD, Lewis B. Silverman, MD, Stephen E. Sallan, MD, Alejandro Gutierrez, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 367.
https://doi.org/10.1182/blood.V130.Suppl_1.367.367
Published: 2017
Journal Articles

Genetically-Defined Diffuse Large B-Cell Lymphoma Subsets Arise By Distinct Pathogenetic Mechanisms and Predict Outcome

Bjoern Chapuy, MD PhD, Chip Stewart, PhD, Andrew Dunford, MS, Jaegil Kim, PhD, Atanas Kamburow, PhD, Robert A. Redd, MS, Michael Lawrence, PhD, Margaretha G.M. Roemer, MSc, Amy Li, Marita Ziepert, PhD, Annette M. Staiger, PhD, Jeremiah Wala, Matthew D. Ducar, MS, Ignaty Leshchiner, PhD, Esther Rheinbay, PhD, Amaro Taylor-Weiner, BS, Caroline Coughlin, BS, Julian Hess, Chandra Pedamallu, Dimitri Livitz, Daniel Rosebrock, Mara Rosenberg, Adam Tracy, Heike Horn, Paul van Hummelen, Andrew L Feldman, MD, Brian K Link, MD, Anne J Novak, PhD, James R. Cerhan, MD PhD, Thomas M Habermann, MD, Reiner Siebert, PhD, Andreas Rosenwald, Aaron R. Thorner, PhD, Matthew Meyerson, MDPhD, Todd R. Golub, MD, Rameen Beroukhim, Gerald Wulf, MD, German Ott, MD, Scott J. Rodig, MDPhD, Stefano Monti, PhD, Donna S. Neuberg, ScD, Markus Loeffler, MD, Michael Pfreundschuh, MD, Lorenz Trümper, MD, Gad Getz, PhD, Margaret A. Shipp, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 38.
https://doi.org/10.1182/blood.V130.Suppl_1.38.38
Published: 2017
Journal Articles

Longitudinal Analyses of the Genomic, Transcriptomic, and T Cell Repertoire in Diffuse Large B Cell Lymphoma Demonstrates Changes in Signaling and Immune Recognition at Relapse

Shamzah Araf, MRCP, MBBS, Koorosh Korfi, PhD BSc, Ai Nagano, PhD, Thomas E C Cummin, MRCP MBBCh BSc, Michael Bentley, PhD, Aaron R. Thorner, PhD, Margaret Ashton-Key, MD, Maria Calaminici, MD PhD, Andrew James Clear, BSc, Andrew Davies, PhD, Sharon Barrans, Suzan Van Hoppe, Cathy Burton, Simon Rule, MD, Nicola Crosbie, Daniel Painter, BSc, Alexandra Smith, PhD, David M. Weinstock, MD, David R Westhead, Jessica Okosun, MD PhD, John G. Gribben, MDDSc FMedSci, Peter Johnson, MD FRCP, Jude Fitzgibbon, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2734.
https://doi.org/10.1182/blood.V130.Suppl_1.2734.2734
Published: 2017
Journal Articles

Diffuse Large B-Cell Lymphoma Patient-Derived Xenograft Models Capture Molecular and Biologic Heterogeneity and Inform Therapy

Bjoern Chapuy, MDPhD, Honwei Cheng, MDPhD, Akira Watahiki, MDPhD, Matthew D Ducar, PhD, Daniel Gusenleitner, MS, Linfeng Chen, PhD, Margaretha GM Roemer, MS, Jing Quyang, PhD, Amanda L Christie, B.S., Liye Zhang, PhD, Yuxiang Tan, Ryan P Abo, PhD, Frederike Bonin, Aaron R Thorner, PhD, Heather H. Sun, Geraldine S Pinkus, MD, Paul van Hummelen, PhD, Gerald G Wulf, MD, Jon C Aster, MDPhD, David M Weinstock, MD, Stefano Monti, PhD, Scott J Rodig, MD PhD, Yuzhuo Wang, PhD, Margaret A. Shipp, MD
Journal: Blood
Blood (2015) 126 (23): 817.
https://doi.org/10.1182/blood.V126.23.817.817
Published: 2015