Testing for t(3;8) in MYC/BCL6 re-arranged large B cell lymphoma identifies a high risk subgroup with inferior survival

Maybury, Bernard Douglas; James, Lisa Jane; Phillips, Neil; Venkatadasari, Indrani; Qureshi, Iman; Riley, James William Elliot; Talbot, Georgina; Moosai, Shivir; Giles, Hannah Victoria; Chadderton, Nicola; Dowds, James; Rakesh, Pallav; Crosland, Henry; Haslam, Aidan; Lane, Sarah; Vega Gonzalez, Monica; Davies, David; Cherian, George; Shenouda, Amir; Kaudlay Sathyanarayana, Praveen Kumar; Starczynski, Jane; Rudzki, Zbigniew; Chaganti, Sridhar

doi:10.1182/blood.2024024048

A reciprocal t(3;8) BCL6::MYC fusion is common in large B cell lymphoma (LBCL) with MYC and BCL6 disruption. These pseudo-double hit cases are not adverse, whereas t(3;8) negative MYC/BCL6 lymphoma has an inferior prognosis relative to other MYC-rearranged LBCL.-

This content is only available as a PDF.

2024

You do not currently have access to this content.

Sign in via your Institution

Testing for t(3;8) in MYC/BCL6 re-arranged large B cell lymphoma identifies a high risk subgroup with inferior survival

Article PDF first page preview

24-Hour Access

Cited By

Email alerts

ASH Publications

American Society of Hematology

Testing for t(3;8) in MYC/BCL6 re-arranged large B cell lymphoma identifies a high risk subgroup with inferior survival

Article PDF first page preview

This feature is available to Subscribers Only

My Account

24-Hour Access

Cited By

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only