During the publication process, an error was introduced into the figure on page 2306. “17q−” should read “17p−.” The publisher apologizes for the error, which has been corrected in the online version of the article.
Different diagnostic methods are applied to determine clinically relevant genetic markers in CLL. Fluorescence in situ hybridization (FISH) is performed to detect the deletions of 11q, 13q, and 17p, as well as trisomy 12, whereas the IGHV and TP53 mutation status is determined by sequencing (Sanger sequencing and/or NGS). Karyotypic complexity is determined by cytogenetic analysis, counting both numerical and structural chromosomal aberrations.
Different diagnostic methods are applied to determine clinically relevant genetic markers in CLL. Fluorescence in situ hybridization (FISH) is performed to detect the deletions of 11q, 13q, and 17p, as well as trisomy 12, whereas the IGHV and TP53 mutation status is determined by sequencing (Sanger sequencing and/or NGS). Karyotypic complexity is determined by cytogenetic analysis, counting both numerical and structural chromosomal aberrations.
This feature is available to Subscribers Only
Sign In or Create an Account Close Modal