Abstract
A peculiar feature of the myelodysplastic syndrome (MDS) defined as refractory anemia with ringed sideroblasts (RARS) is that CD34+ cells have a distinct expression profile characterized by up-regulation of mitochondrial-related genes and, in particular, of those of heme synthesis, e.g., ALAS2 [
Blood
2006
;108
:337
–45Author notes
Disclosure: No relevant conflicts of interest to declare.
2007, The American Society of Hematology
2007
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