Though protein-tyrosine kinases get most of the attention, there is growing evidence that serine/threonine kinases (S/TKs) also play an important role in amplifying platelet activation responses following exposure to low-dose platelet agonists. For example, granule secretion is markedly impaired in platelets from mice deficient in either isoform of the STKs Akt1 (
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Disclosure: No relevant conflicts of interest to declare.
2006, The American Society of Hematology
2006
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