Abstract
Nef, an accessory protein of HIV−1, has been shown to be critical for both high viral loads and progression to AIDS. We recently demonstrated that Nef inhibited the bioactivities of M-CSF, a monocytes/macrophages-specific cytokine (
Blood
105
: 3230
–3237, 2005
Topics:
hiv-1,
macrophage colony-stimulating factor,
macrophage colony-stimulating factor receptor,
cytokine,
acquired immunodeficiency syndrome,
granulocyte-macrophage colony-stimulating factor,
receptors, granulocyte-macrophage colony-stimulating factor,
recombinant granulocyte-macrophage colony-stimulating factors,
src-family kinases,
viral load result
Disclosures: Supported by Health and Labour Sciences Research Grants from the Ministry of Health, Labour and Welfare of Japan.
Author notes
*
Corresponding author
2006, The American Society of Hematology
2006
This feature is available to Subscribers Only
Sign In or Create an Account Close Modal