Abstract
gp130 is the common signaling receptor subunit for the IL-6 family of cytokines. We have previously shown that expression of a dominant negative (DN) gp130 inhibitory protein in MDA-MB-231 breast cancer cells decreased tumor invasion and angiogenesis in an orthotopic animal model (
Cancer Research
64
:6924
, 2004
Author notes
Corresponding author
2005, The American Society of Hematology
2005
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