Harir et al. Oncogenic Kit controls neoplastic mast cell growth through a Stat5/PI3-kinase signaling cascade. Blood. 2008;112(6):2463-2473.

doi:10.1182/blood-2009-06-230177

ERRATUM| August 20, 2009

On page 2467 of the September 15, 2008, issue, Table 1 in the online version, which now differs from the print was omitted. Table 1 is shown below. The error was corrected version.

2009

Table 1

Patient characteristics

No.	Diagnosis*	Age	Sex	Serum tryptase, ng/mL	Percent infiltration of BM with MCs	MC positive for P-Y-Stat5	MC positive for P-S-Akt
1	SSM	47	F	153	25	+	+
2	SSM	34	M	937	50	+	+
3	ISM	66	F	17	2	+	+
4	ISM	39	M	17	5	+	+
5	ISM	70	M	28	2	+	+
6	ISM	64	M	164	15	+	ND
7	ISM	62	F	26	10	+	ND
8	ISM	53	M	50	15	+	ND
9	ISM	48	F	54	5	+	ND
10	ISM	43	M	20	5	+	+
11	ISM	32	F	18	5	+	ND
12	ISM	32	M	36	5	+	+
13	ISM	30	M	148	10	+	ND
14	ASM	40	F	ND	5	+	ND
15	MCL	60	M	285	70	+	ND

No.	Diagnosis*	Age	Sex	Serum tryptase, ng/mL	Percent infiltration of BM with MCs	MC positive for P-Y-Stat5	MC positive for P-S-Akt
1	SSM	47	F	153	25	+	+
2	SSM	34	M	937	50	+	+
3	ISM	66	F	17	2	+	+
4	ISM	39	M	17	5	+	+
5	ISM	70	M	28	2	+	+
6	ISM	64	M	164	15	+	ND
7	ISM	62	F	26	10	+	ND
8	ISM	53	M	50	15	+	ND
9	ISM	48	F	54	5	+	ND
10	ISM	43	M	20	5	+	+
11	ISM	32	F	18	5	+	ND
12	ISM	32	M	36	5	+	+
13	ISM	30	M	148	10	+	ND
14	ASM	40	F	ND	5	+	ND
15	MCL	60	M	285	70	+	ND

BM indicates bone marrow; F, female; M, male; MC, mast cells; SSM, smoldering systemic mastocytosis; ISM, indolent systemic mastocytosis; ASM, aggressive systemic mastocytosis; MCL, mast cell leukemia; and ND, not determined.

All patients examined exhibited the Kit D816V as determined by RT-PCR and RFLP analysis.

Harir et al. Oncogenic Kit controls neoplastic mast cell growth through a Stat5/PI3-kinase signaling cascade. Blood. 2008;112(6):2463-2473.

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No.	Diagnosis*	Age	Sex	Serum tryptase, ng/mL	Percent infiltration of BM with MCs	MC positive for P-Y-Stat5	MC positive for P-S-Akt
1	SSM	47	F	153	25	+	+
2	SSM	34	M	937	50	+	+
3	ISM	66	F	17	2	+	+
4	ISM	39	M	17	5	+	+
5	ISM	70	M	28	2	+	+
6	ISM	64	M	164	15	+	ND
7	ISM	62	F	26	10	+	ND
8	ISM	53	M	50	15	+	ND
9	ISM	48	F	54	5	+	ND
10	ISM	43	M	20	5	+	+
11	ISM	32	F	18	5	+	ND
12	ISM	32	M	36	5	+	+
13	ISM	30	M	148	10	+	ND
14	ASM	40	F	ND	5	+	ND
15	MCL	60	M	285	70	+	ND

No.	Diagnosis*	Age	Sex	Serum tryptase, ng/mL	Percent infiltration of BM with MCs	MC positive for P-Y-Stat5	MC positive for P-S-Akt
1	SSM	47	F	153	25	+	+
2	SSM	34	M	937	50	+	+
3	ISM	66	F	17	2	+	+
4	ISM	39	M	17	5	+	+
5	ISM	70	M	28	2	+	+
6	ISM	64	M	164	15	+	ND
7	ISM	62	F	26	10	+	ND
8	ISM	53	M	50	15	+	ND
9	ISM	48	F	54	5	+	ND
10	ISM	43	M	20	5	+	+
11	ISM	32	F	18	5	+	ND
12	ISM	32	M	36	5	+	+
13	ISM	30	M	148	10	+	ND
14	ASM	40	F	ND	5	+	ND
15	MCL	60	M	285	70	+	ND

No.	Diagnosis*	Age	Sex	Serum tryptase, ng/mL	Percent infiltration of BM with MCs	MC positive for P-Y-Stat5	MC positive for P-S-Akt
1	SSM	47	F	153	25	+	+
2	SSM	34	M	937	50	+	+
3	ISM	66	F	17	2	+	+
4	ISM	39	M	17	5	+	+
5	ISM	70	M	28	2	+	+
6	ISM	64	M	164	15	+	ND
7	ISM	62	F	26	10	+	ND
8	ISM	53	M	50	15	+	ND
9	ISM	48	F	54	5	+	ND
10	ISM	43	M	20	5	+	+
11	ISM	32	F	18	5	+	ND
12	ISM	32	M	36	5	+	+
13	ISM	30	M	148	10	+	ND
14	ASM	40	F	ND	5	+	ND
15	MCL	60	M	285	70	+	ND

No.	Diagnosis*	Age	Sex	Serum tryptase, ng/mL	Percent infiltration of BM with MCs	MC positive for P-Y-Stat5	MC positive for P-S-Akt
1	SSM	47	F	153	25	+	+
2	SSM	34	M	937	50	+	+
3	ISM	66	F	17	2	+	+
4	ISM	39	M	17	5	+	+
5	ISM	70	M	28	2	+	+
6	ISM	64	M	164	15	+	ND
7	ISM	62	F	26	10	+	ND
8	ISM	53	M	50	15	+	ND
9	ISM	48	F	54	5	+	ND
10	ISM	43	M	20	5	+	+
11	ISM	32	F	18	5	+	ND
12	ISM	32	M	36	5	+	+
13	ISM	30	M	148	10	+	ND
14	ASM	40	F	ND	5	+	ND
15	MCL	60	M	285	70	+	ND

Harir et al. Oncogenic Kit controls neoplastic mast cell growth through a Stat5/PI3-kinase signaling cascade. Blood. 2008;112(6):2463-2473.

Contents

Data & Figures

Supplemental data

References

Related

Related

Cited By

Email alerts

ASH Publications

American Society of Hematology

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No.	Diagnosis*	Age	Sex	Serum tryptase, ng/mL	Percent infiltration of BM with MCs	MC positive for P-Y-Stat5	MC positive for P-S-Akt
1	SSM	47	F	153	25	+	+
2	SSM	34	M	937	50	+	+
3	ISM	66	F	17	2	+	+
4	ISM	39	M	17	5	+	+
5	ISM	70	M	28	2	+	+
6	ISM	64	M	164	15	+	ND
7	ISM	62	F	26	10	+	ND
8	ISM	53	M	50	15	+	ND
9	ISM	48	F	54	5	+	ND
10	ISM	43	M	20	5	+	+
11	ISM	32	F	18	5	+	ND
12	ISM	32	M	36	5	+	+
13	ISM	30	M	148	10	+	ND
14	ASM	40	F	ND	5	+	ND
15	MCL	60	M	285	70	+	ND

No.	Diagnosis*	Age	Sex	Serum tryptase, ng/mL	Percent infiltration of BM with MCs	MC positive for P-Y-Stat5	MC positive for P-S-Akt
1	SSM	47	F	153	25	+	+
2	SSM	34	M	937	50	+	+
3	ISM	66	F	17	2	+	+
4	ISM	39	M	17	5	+	+
5	ISM	70	M	28	2	+	+
6	ISM	64	M	164	15	+	ND
7	ISM	62	F	26	10	+	ND
8	ISM	53	M	50	15	+	ND
9	ISM	48	F	54	5	+	ND
10	ISM	43	M	20	5	+	+
11	ISM	32	F	18	5	+	ND
12	ISM	32	M	36	5	+	+
13	ISM	30	M	148	10	+	ND
14	ASM	40	F	ND	5	+	ND
15	MCL	60	M	285	70	+	ND