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Journal Articles

Lentiviral correction of enzymatic activity restrains macrophage inflammation in adenosine deaminase 2 deficiency

Matteo Zoccolillo, Immacolata Brigida, Federica Barzaghi, Serena Scala, Raisa Jofra Hernández, Luca Basso-Ricci, Mariasilvia Colantuoni, Emanuela Pettinato, Lucia Sergi Sergi, Giulia Milardi, Paola Capasso, Angelo Lombardo, Silvia Gregori, Francesca Sanvito, Francesca Schena, Simone Cesaro, Francesca Conti, Andrea Pession, Fabio Benedetti, Marco Gattorno, Pui Y. Lee, Luigi Naldini, Maria Pia Cicalese, Alessandro Aiuti, Alessandra Mortellaro
Journal: Blood Advances
Blood Adv (2021) 5 (16): 3174–3187.
https://doi.org/10.1182/bloodadvances.2020003811
Published: 2021
Includes: Supplemental data
Journal Articles

Patients with triple-negative, JAK2 V617F- and CALR -mutated essential thrombocythemia share a unique gene expression signature

Samah Alimam, William Villiers, Richard Dillon, Michael Simpson, Manohursingh Runglall, Alexander Smith, Prodromos Chatzikyriakou, Paul Lavender, Anju Kanda, Ken Mills, Beatriz Bellosillo Paricio, James Kaufman-Cook, Sophie Ord, Shahram Kordasti, Deepti Radia, Claire Woodley, Yvonne Francis, Ghulam Mufti, Donal P. McLornan, Claire N. Harrison
Journal: Blood Advances
Blood Adv (2021) 5 (4): 1059–1068.
https://doi.org/10.1182/bloodadvances.2020003172
Published: 2021
Includes: Supplemental data
Journal Articles

Improving the antitumor activity of R-CHOP with NGR-hTNF in primary CNS lymphoma: final results of a phase 2 trial

Clinical Trials & Observations
Andrés J. M. Ferreri, Teresa Calimeri, Maurilio Ponzoni, Flavio Curnis, Gian Marco Conte, Eloise Scarano, Eltjona Rrapaj, Daniela De Lorenzo, Dario Cattaneo, Federico Fallanca, Alessandro Nonis, Marco Foppoli, Paolo Lopedote, Giovanni Citterio, Letterio S. Politi, Marianna Sassone, Piera Angelillo, Elena Guggiari, Sara Steffanoni, Vittoria Tarantino, Fabio Ciceri, Claudio Bordignon, Nicoletta Anzalone, Angelo Corti
Journal: Blood Advances
Blood Adv (2020) 4 (15): 3648–3658.
https://doi.org/10.1182/bloodadvances.2020002270
Published: 2020
Includes: Multimedia, Supplemental data
Journal Articles

Immunomodulatory drugs suppress Th1-inducing ability of dendritic cells but enhance Th2-mediated allergic responses

Vien Phan, Tomoki Ito, Muneo Inaba, Yoshiko Azuma, Kayoko Kibata, Noriko Inagaki-Katashiba, Akihiro Tanaka, Atsushi Satake, Shosaku Nomura
Journal: Blood Advances
Blood Adv (2020) 4 (15): 3572–3585.
https://doi.org/10.1182/bloodadvances.2019001410
Published: 2020
Includes: Supplemental data
Journal Articles

Rapidly expanded partially HLA DRB1–matched fungus-specific T cells mediate in vitro and in vivo antifungal activity

Gloria Castellano-González, Helen M. McGuire, Fabio Luciani, Leighton E. Clancy, Ziduo Li, Selmir Avdic, Brendan Hughes, Mandeep Singh, Barbara Fazekas de St Groth, Giorgia Renga, Marilena Pariano, Marina M. Bellet, Luigina Romani, David J. Gottlieb
Journal: Blood Advances
Blood Adv (2020) 4 (14): 3443–3456.
https://doi.org/10.1182/bloodadvances.2020001565
Published: 2020
Includes: Supplemental data
Journal Articles

Runx1 negatively regulates inflammatory cytokine production by neutrophils in response to Toll-like receptor signaling

Dana C. Bellissimo, Chia-hui Chen, Qin Zhu, Sumedha Bagga, Chung-Tsai Lee, Bing He, Gerald B. Wertheim, Martha Jordan, Kai Tan, G. Scott Worthen, D. Gary Gilliland, Nancy A. Speck
Journal: Blood Advances
Blood Adv (2020) 4 (6): 1145–1158.
https://doi.org/10.1182/bloodadvances.2019000785
Published: 2020
Includes: Supplemental data
Journal Articles

Defective negative regulation of Toll-like receptor signaling leads to excessive TNF-α in myeloproliferative neoplasm

Clinical Trials & Observations
Hew Yeng Lai, Stefan A. Brooks, Brianna M. Craver, Sarah J. Morse, Thanh Kim Nguyen, Nahideh Haghighi, Michael R. Garbati, Angela G. Fleischman
Journal: Blood Advances
Blood Adv (2019) 3 (2): 122–131.
https://doi.org/10.1182/bloodadvances.2018026450
Published: 2019
Includes: Supplemental data
Journal Articles

TLR2 agonism reverses chemotherapy-induced neutropenia in Macaca fascicularis

Nicholas J. Laping, Michael P. DeMartino, Joshua E. Cottom, Jeffrey M. Axten, John G. Emery, Jeffrey H. Guss, Miriam Burman, James J. Foley, Mui Cheung, Allen Oliff, Sanjay Kumar
Journal: Blood Advances
Blood Adv (2017) 1 (26): 2553–2562.
https://doi.org/10.1182/bloodadvances.2017010611
Published: 2017
Journal Articles

TAK1 inhibition subverts the osteoclastogenic action of TRAIL while potentiating its antimyeloma effects

Hirofumi Tenshin, Jumpei Teramachi, Asuka Oda, Ryota Amachi, Masahiro Hiasa, Ariunzaya Bat-Erdene, Keiichiro Watanabe, Masami Iwasa, Takeshi Harada, Shiro Fujii, Kumiko Kagawa, Kimiko Sogabe, Shingen Nakamura, Hirokazu Miki, Kiyoe Kurahashi, Sumiko Yoshida, Kenichi Aihara, Itsuro Endo, Eiji Tanaka, Toshio Matsumoto, Masahiro Abe
Journal: Blood Advances
Blood Adv (2017) 1 (24): 2124–2137.
https://doi.org/10.1182/bloodadvances.2017008813
Published: 2017
Includes: Supplemental data
Journal Articles

WNT ligands contribute to the immune response during septic shock and amplify endotoxemia-driven inflammation in mice

Marcela Gatica-Andrades, Dimitrios Vagenas, Jessica Kling, Tam T. K. Nguyen, Helen Benham, Ranjeny Thomas, Heinrich Körner, Bala Venkatesh, Jeremy Cohen, Antje Blumenthal
Journal: Blood Advances
Blood Adv (2017) 1 (16): 1274–1286.
https://doi.org/10.1182/bloodadvances.2017006163
Published: 2017
Includes: Supplemental data
Journal Articles

Th17 plasticity and transition toward a pathogenic cytokine signature are regulated by cyclosporine after allogeneic SCT

Kate H. Gartlan, Antiopi Varelias, Motoko Koyama, Renee J. Robb, Kate A. Markey, Karshing Chang, Andrew N. Wilkinson, David Smith, Md Ashik Ullah, Rachel D. Kuns, Neil C. Raffelt, Stuart D. Olver, Katie E. Lineburg, Bianca E. Teal, Melody Cheong, Michele W. L. Teng, Mark J. Smyth, Siok-Keen Tey, Kelli P. A. MacDonald, Geoffrey R. Hill
Journal: Blood Advances
Blood Adv (2017) 1 (6): 341–351.
https://doi.org/10.1182/bloodadvances.2016002980
Published: 2017