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Valder R Arruda
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Journal Articles

Loss of factor VIII in zebrafish rebalances antithrombin deficiency but has a limited bleeding diathesis

Open Access
Raghunath Azhwar, Catherine E. Richter, Megan S Griffin, Sylvia M Emly, Murat Yaman, Valder R Arruda, Benjamin J Samelson-Jones, Jordan A Shavit
Journal: Blood Advances
Blood Adv bloodadvances.2024013143.
https://doi.org/10.1182/bloodadvances.2024013143
Published: 2025
Includes: Supplemental data
Journal Articles

Why is AAV FVIII gene therapy not approved by the US Food and Drug Administration yet?

Free
Clinical Trials & Observations
Valder R. Arruda
Journal: Blood Advances
Blood Adv (2021) 5 (20): 4313.
https://doi.org/10.1182/bloodadvances.2021004760
Published: 2021
Includes: Supplemental data
Journal Articles

Evolutionary insights into coagulation factor IX Padua and other high-specific-activity variants

Free
Benjamin J. Samelson-Jones, Jonathan D. Finn, Leslie J. Raffini, Elizabeth P. Merricks, Rodney M. Camire, Timothy C. Nichols, Valder R. Arruda
Journal: Blood Advances
Blood Adv (2021) 5 (5): 1324–1332.
https://doi.org/10.1182/bloodadvances.2019000405
Published: 2021
Includes: Supplemental data
Journal Articles

Complete correction of hemophilia B phenotype by FIX-Padua skeletal muscle gene therapy in an inhibitor-prone dog model

Free
Robert A. French, Benjamin J. Samelson-Jones, Glenn P. Niemeyer, Clinton D. Lothrop, Jr, Elizabeth P. Merricks, Timothy C. Nichols, Valder R. Arruda
Journal: Blood Advances
Blood Adv (2018) 2 (5): 505–508.
https://doi.org/10.1182/bloodadvances.2017015313
Published: 2018
Includes: Supplemental data