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Toshiaki Shirai
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Journal Articles

Heme activates platelets and exacerbates rhabdomyolysis-induced acute kidney injury via CLEC-2 and GPVI/FcRγ

Clinical Trials & Observations
Saori Oishi, Nagaharu Tsukiji, Shimon Otake, Naoki Oishi, Tomoyuki Sasaki, Toshiaki Shirai, Yuri Yoshikawa, Katsuhiro Takano, Hideyuki Shinmori, Takeshi Inukai, Tetsuo Kondo, Katsue Suzuki-Inoue
Journal: Blood Advances
Blood Adv (2021) 5 (7): 2017–2026.
https://doi.org/10.1182/bloodadvances.2020001698
Published: 2021
Includes: Supplemental data
Journal Articles

Hepatic thrombopoietin gene silencing reduces platelet count and breast cancer progression in transgenic MMTV-PyMT mice

Toshiaki Shirai, Alexey S. Revenko, Justin Tibbitts, Anh T. P. Ngo, Annachiara Mitrugno, Laura D. Healy, Jennifer Johnson, Erik I. Tucker, Monica T. Hinds, Lisa M. Coussens, Owen J. T. McCarty, Brett P. Monia, András Gruber
Journal: Blood Advances
Blood Adv (2019) 3 (20): 3080–3091.
https://doi.org/10.1182/bloodadvances.2019000250
Published: 2019
Includes: Supplemental data
Journal Articles

Cobalt hematoporphyrin inhibits CLEC-2–podoplanin interaction, tumor metastasis, and arterial/venous thrombosis in mice

Nagaharu Tsukiji, Makoto Osada, Tomoyuki Sasaki, Toshiaki Shirai, Kaneo Satoh, Osamu Inoue, Norihiko Umetani, Chihiro Mochizuki, Tamio Saito, Soichi Kojima, Hideyuki Shinmori, Yukio Ozaki, Katsue Suzuki-Inoue
Journal: Blood Advances
Blood Adv (2018) 2 (17): 2214–2225.
https://doi.org/10.1182/bloodadvances.2018016261
Published: 2018
Includes: Supplemental data