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Journal Articles

Azacytidine Inhibits Megakaryopoiesis Via the Induction of Immunogenic RNA Species and Activation of Type-I Interferon Signaling

Ujunwa Cynthia Okoye-Okafor, MS,PhD, Komal Kumar Javarappa, PhD, Dimitrios Tsallos, BSc(Hons),MSc, Joseph J Saad, MSc, BSc, Lumie Benard, Victor Thiruthuvanathan, M.S, Sally Cole, Madhuri Tatiparthy, M.S., Stephen Ruiz, B.Sc, Stefanie DeFronzo, Celine Pallaud, PhD, Pedro Marques Ramos, PhD, Amit Verma, MBBS, Aditi Shastri, MD, Caroline A Heckman, PhD, Britta Will, PhD

Blood (2019) 134 (Supplement_1): 1280.

https://doi.org/10.1182/blood-2019-131461

Published: 2019

Journal Articles

The Tissue Factor/Thrombin/Protease-Activated Receptor 1 Pathway Enhances Double-Strand RNA Induced Immune Responses in Macrophages

Silvio Antoniak, PhD, Kohei Tatsumi, MD,PhD, Nigel Mackman, PhD

Blood (2014) 124 (21): 4114.

https://doi.org/10.1182/blood.V124.21.4114.4114

Published: 2014

Journal Articles

New Mechanism in Anti Tumor Activity of Poly (I:C): Modulation of Tumor-Associated Myeloid Derived Suppressor Cells in Murine Model of Breast Cancer

Parvin Forghani, PhD, Edmund K. Waller, MD PhD

Blood (2014) 124 (21): 2728.

https://doi.org/10.1182/blood.V124.21.2728.2728

Published: 2014

Journal Articles

Combination Immunotherapy After ASCT for Multiple Myeloma (MM) Using MAGE-A3/Poly-ICLC Immunizations Followed by Vaccine-Primed and Activated Autologous T-Cells

Blood (2012) 120 (21): 352.

https://doi.org/10.1182/blood.V120.21.352.352

Published: 2012

Journal Articles

Cross-Presentation by Host CD8α + dendritic Cells Augments Graft-Versus-Tumor Effect without Aggravating Graft-Versus-Host Disease After Allogeneic BMT

Tomomi Toubai, MD, PhD, Yaping Sun, MD, PhD, Isao Tawara, MD, PhD, Chen Liu, PhD, Pavan Reddy, M.D.

Blood (2011) 118 (21): 310.

https://doi.org/10.1182/blood.V118.21.310.310

Published: 2011

Journal Articles

Toll-Like Receptor 3 Activation Is Involved in Venous Thrombosis Development,

Catherine A Lemarie, Sandrine Laurance, Mark Blostein

Blood (2011) 118 (21): 3277.

https://doi.org/10.1182/blood.V118.21.3277.3277

Published: 2011

Journal Articles

Expression of Toll-Like Receptors on Peripheral Blood Cells After Allogeneic Stem Cell Transplantation: Ongoing Results of a Prospective Study

Cristina Skert, MD, Emirena Garrafa, Jr, Manuela Fogli, Simona Fiorentini, Doris Ricotta, Luigi Caimi, Carla Filì, Annalisa Peli, Cesare Bergonzi, Michele Malagola, Martinelli Giovanni, MD, Ilaria Iacobucci, Alessandro Turra, Mario Arpinati, Federica Cattina, Arnaldo Caruso, Domenico Russo

Blood (2010) 116 (21): 4704.

https://doi.org/10.1182/blood.V116.21.4704.4704

Published: 2010

Journal Articles

Self-Complementary AAV Vectors Cause a Substantially Heightened TLR9-Dependent Innate Immune Response In the Liver

Ashley T Martino, Ph.D., Masataka Suzuki, Ph.D., David Markusic, Irene Zolotukhin, M.S., Daniel A Muruve, M.D., Brendan Lee, MD, PhD, Roland W Herzog, PhD

Blood (2010) 116 (21): 252.

https://doi.org/10.1182/blood.V116.21.252.252

Published: 2010

Journal Articles

TLR4-Agonist Stimulated Human Multipotent Mesenchymal Stromal Cells Enhance Both Hematopoietic Progenitors and Myeloid Differentiation

Patrick Ziegler, PhD, Steffen Boettcher, Guido Garavaglia, MD, Markus G. Manz, MD

Blood (2008) 112 (11): 1366.

https://doi.org/10.1182/blood.V112.11.1366.1366

Published: 2008

Journal Articles

Augmentation of Vasculogenesis by Injected Human Hematopoietic Stem Cells in Response to Ischemia Follows Early Activation of Innate Immune Response.

Marcie R. Finney, MS, Laura R. Fanning, BS, Margaret Kozik, BS, Shigemi Matsuyama, PhD, Matthew E. Joseph, BS, Johnathan L. Goldberg, MD, Nicholas J. Greco, PhD, Peter Haviernik, PhD, Pingfu Fu, PhD, Vincent J. Pompili, MD, Mary J. Laughlin, MD

Blood (2007) 110 (11): 4051.

https://doi.org/10.1182/blood.V110.11.4051.4051

Published: 2007

Journal Articles

TLR Agonist Induced Cytokine Production in Human Multipotent Mesenchymal Stromal Cells: A Potential Mechanism How Hematopoiesis Is Enhanced during Generalized Inflammatory Conditions.

Steffen Boettcher, Patrick Ziegler, Ph.D., Markus G. Manz, M.D.

Blood (2007) 110 (11): 1411.

https://doi.org/10.1182/blood.V110.11.1411.1411

Published: 2007

Journal Articles

Double-Stranded RNA Acts as a Strong Danger Signal in Human Myeloid Leukemia Cells Leading to Increased Immunogenicity.

Zwi N. Berneman, MD, PhD, Evelien L.J.M. Smits, M.Sc., Peter Ponsaerts, Ph.D., Nathalie Cools, M.Sc., Ann L.R. Van de Velde, M.D., Alain P. Gadisseur, M.D., Ph.D., Wilfried A. Schroyens, M.D., Ph.D., Viggo F.I. Van Tendeloo, Ph.D.

Blood (2006) 108 (11): 5203.

https://doi.org/10.1182/blood.V108.11.5203.5203

Published: 2006

Journal Articles

Post-Transplant Administration of Flt3 Ligand Enhances Innate Cellular-Mediated Immune Responses to Toll-Like Receptor Agonists in Syngeneic Bone Marrow Transplant Mice.

Jeffery J. Auletta, MD, Laura Xu, MD, Jennifer L. DeVecchio, BA, Frederick P. Heinzel, MD

Blood (2005) 106 (11): 5229.

https://doi.org/10.1182/blood.V106.11.5229.5229

Published: 2005

Journal Articles

Toll-Like Receptor Agonists Induce Secretion of Immunomodulatory Soluble Factors from Human Mesenchymal Stem Cells.

Jeffery J. Auletta, MD, Basabi Maitra, BS, Emese Szekely, BS, Omer N. Koc, MD

Blood (2005) 106 (11): 1394.

https://doi.org/10.1182/blood.V106.11.1394.1394

Published: 2005

Journal Articles

Pathogen-Associated Molecular Patterns Are Growth and Survival Factors for Human Myeloma Cells through Toll-Like Receptors.

Gaetan Jego, PhD, Catherine Pellat-Deceunynck, PhD, Catherine David, MS, Bataille Regis, MD, PhD

Blood (2005) 106 (11): 3403.

https://doi.org/10.1182/blood.V106.11.3403.3403

Published: 2005

Journal Articles

Toll-Like Receptor 3 Is a Mediator of the Innate Immune Response to Cytomegalovirus in Immature Dendritic Cells.

Hermann Einsele, MD, Michael Bonin, MD, Florian Gebhardt, Tobias Kessler, Susanne Riegler, MD, Ziad Haddad, Holger Hebart, MD, Juergen Loeffler, PhD

Blood (2004) 104 (11): 731.

https://doi.org/10.1182/blood.V104.11.731.731

Published: 2004

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Azacytidine Inhibits Megakaryopoiesis Via the Induction of Immunogenic RNA Species and Activation of Type-I Interferon Signaling

The Tissue Factor/Thrombin/Protease-Activated Receptor 1 Pathway Enhances Double-Strand RNA Induced Immune Responses in Macrophages

New Mechanism in Anti Tumor Activity of Poly (I:C): Modulation of Tumor-Associated Myeloid Derived Suppressor Cells in Murine Model of Breast Cancer

Combination Immunotherapy After ASCT for Multiple Myeloma (MM) Using MAGE-A3/Poly-ICLC Immunizations Followed by Vaccine-Primed and Activated Autologous T-Cells

Cross-Presentation by Host CD8α + dendritic Cells Augments Graft-Versus-Tumor Effect without Aggravating Graft-Versus-Host Disease After Allogeneic BMT

Toll-Like Receptor 3 Activation Is Involved in Venous Thrombosis Development,

Expression of Toll-Like Receptors on Peripheral Blood Cells After Allogeneic Stem Cell Transplantation: Ongoing Results of a Prospective Study

Self-Complementary AAV Vectors Cause a Substantially Heightened TLR9-Dependent Innate Immune Response In the Liver

TLR4-Agonist Stimulated Human Multipotent Mesenchymal Stromal Cells Enhance Both Hematopoietic Progenitors and Myeloid Differentiation

Augmentation of Vasculogenesis by Injected Human Hematopoietic Stem Cells in Response to Ischemia Follows Early Activation of Innate Immune Response.

TLR Agonist Induced Cytokine Production in Human Multipotent Mesenchymal Stromal Cells: A Potential Mechanism How Hematopoiesis Is Enhanced during Generalized Inflammatory Conditions.

Double-Stranded RNA Acts as a Strong Danger Signal in Human Myeloid Leukemia Cells Leading to Increased Immunogenicity.

Post-Transplant Administration of Flt3 Ligand Enhances Innate Cellular-Mediated Immune Responses to Toll-Like Receptor Agonists in Syngeneic Bone Marrow Transplant Mice.

Toll-Like Receptor Agonists Induce Secretion of Immunomodulatory Soluble Factors from Human Mesenchymal Stem Cells.

Pathogen-Associated Molecular Patterns Are Growth and Survival Factors for Human Myeloma Cells through Toll-Like Receptors.

Toll-Like Receptor 3 Is a Mediator of the Innate Immune Response to Cytomegalovirus in Immature Dendritic Cells.

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