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Journal Articles

Spred1 Insufficiency in the Hematopoietic and/or Vascular Compartments of the Bone Marrow (BM) Niche Promotes Aggressive Leukemogenesis in Chronic Myelogenous Leukemia (CML)

Junjing Qiao, MD PhD, Dandan Zhao, MD, Le Xuan Truong Nguyen, PhD, Herman Wu, BS, Gang Liu, PhD, Shanshan Suo, MD, Huafeng Wang, Yasmin Elhajmoussa, Chen Liang, MD, David Snyder, MD, Haris Ali, MD, Steven Rosen, MD, Nadia Carlesso, MD, Ling Li, PhD, Ya-Huei Kuo, PhD, Guido Marcucci, MD, Bin Zhang, PhD

Blood (2019) 134 (Supplement_1): 3791.

https://doi.org/10.1182/blood-2019-127616

Published: 2019

Journal Articles

A Functional Analysis of SNP on Anthracycline-Induced Cardiotoxicity in a Uniform Genetic Background Using CRISPR/Cas9 Mediated Single-Base-Edited iPSCs

Takayuki Nakamura, MD, Shinichi Mizuno, MD PhD, Hidetoshi Ozawa, Yoshitaka Yamasaki, MD, Shuki Oya, MD, Satoshi Morishige, MD, Kazutoshi Aoyama, MD PhD, Maki Ymaguchi, MD PhD, Ritsuko Seki, PhD, Fumihiko Mouri, MD PhD, Koichi Osaki, MD, Koji Nagafuji, MD PhD

Blood (2019) 134 (Supplement_1): 5748.

https://doi.org/10.1182/blood-2019-123932

Published: 2019

Journal Articles

Dual Targeting of Mitochondrial Unfolded Protein Response and BCL2 in Acute Myeloid Leukemia

Ran Zhao, BS, Sarah Zarabi, MD, Takenobu Nii, PhD, Ondrej Halgas, PhD, Yulia Jitkova, PhD, Vivian Ruvolo, Lauren Heese, Yuki Nishida, MD PhD, Gautam M. Borthakur, MD, Kensuke Kojima, MD PhD, Martin Stogniew, Wolfgang Oster, MD, Emil Pai, PhD, Eric Davis, MD, Hagop M. Kantarjian, MD, Aaron D Schimmer, MD PhD, Michael Andreeff, MD PhD, Jo Ishizawa, MD PhD

Blood (2019) 134 (Supplement_1): 2562.

https://doi.org/10.1182/blood-2019-127101

Published: 2019

Journal Articles

Microrna-126 Levels Modulate B-ALL Aggressiveness but Require Tight Regulation to Guarantee Disease Maintenance

Carolina Caserta, Silvia Nucera, MD, Matteo Maria Naldini, Nadia Foligno, Giacomo Desantis, PhD, Fabio Ciceri, MD, Davide Cittaro, PhD, Bernhard Gentner, MD

Blood (2018) 132 (Supplement 1): 2834.

https://doi.org/10.1182/blood-2018-99-115101

Published: 2018

Journal Articles

Platelet Protein Glycosylation in Immune Thrombocytopenia

Elena Monzón Manzano, Raul Justo Sanz, Stuart M Haslam, BSc PhD, Leow Ke Xuan, Anne Dell, PhD, Teresa Álvarez-Roman, Mónica Martín, María Isabel Rivas Pollmar, Ihosvany Fernandez-Bello, Miguel A. Canales, Victor Jimenez-Yuste, Nora Butta, PhD

Blood (2018) 132 (Supplement 1): 2437.

https://doi.org/10.1182/blood-2018-99-114568

Published: 2018

Journal Articles

MYC Functions As a Master Switch for Natural Killer Cell-Mediated Immune Surveillance of Lymphoid Malignancies

Srividya Swaminathan, PhD, Line Dam Heftdal, MS, Daniel F Liefwalker, PhD, Renumathy Dhanasekaran, MD, Anja Deutzmann, PhD, Crista Horton, BS, Adriane Mosley, BS, Mariola Liebersbach, BS, Holden T. Maecker, PhD, Dean Felsher, MD PhD

Blood (2018) 132 (Supplement 1): 2619.

https://doi.org/10.1182/blood-2018-99-110472

Published: 2018

Journal Articles

Genomic and Proteomic Profiling of AF10-Fusion Oncoproteins Reveal Mechanisms of Leukemogenesis and Actionable Targets

Bo-Rui Chen, PhD, Anagha Deshpande, PhD, Maria Kleppe, PhD, Narayana Yeddula, PhD, Sunnie Yoh, PhD, Scott A. Armstrong, MD PhD, Ross L. Levine, MD, Sumit Chanda, PhD, Aniruddha J. Deshpande, PhD

Blood (2018) 132 (Supplement 1): 544.

https://doi.org/10.1182/blood-2018-99-119210

Published: 2018

Journal Articles

Targeting the Glyco-Antigen CD75s with the Tetravalent, Fc-Engineered Antibody 'Ebu-141 Tetra' Induces Potent Killing of B Cell Lymphoma and Plasma Cell Tumors

Katja Klausz, PhD, Amir Karimzadeh-Tabrizi, Malena Buck, Steffen Krohn, Anna-Kathrin Otte, PhD, Christian Kellner, PhD, Giorgio Alberto Croci, MD, Wolfram Klapper, MD, Matthias Peipp, PhD, Martin Gramatzki, MD

Blood (2018) 132 (Supplement 1): 4178.

https://doi.org/10.1182/blood-2018-99-118068

Published: 2018

Journal Articles

Inducible Correction of a RUNX1 Mutation of Human AML Causes a Switch of AML to B-ALL

Chen Wang, PhDcandidate, Yoshihiro Hayashi, MD PhD, Xiongwei Cai, PhD, Xiaomei Yan, MD PhD, Gang Huang, PhD, Yi Zheng, PhD

Blood (2018) 132 (Supplement 1): 1325.

https://doi.org/10.1182/blood-2018-99-116919

Published: 2018

Journal Articles

Improved Pharmacokinetic Profile for BAY 81-8973 Due to Increased Branching and Sialylation of N-Linked Glycans of Recombinant Factor VIII

John M. Teare, PhD, David S. Kates, Anita Shah, Stephen Garger

Blood (2018) 132 (Supplement 1): 1209.

https://doi.org/10.1182/blood-2018-99-113061

Published: 2018

Journal Articles

Repeated Transfusion of Granulocytes to Control Multidrug-Resistant Pseudomonas Aeruginosa Sepsis in Haploidentical Hematopoietic Stem Cell Transplant Patients during Pre-Engraftment Stage

Yixin Hu, MD, Ruonan Sun, Jun Lu, MD, Peifang Xiao, MD, Jie Li, MD, Defei Zheng, MD, Shaoyan Hu, MD PhD

Blood (2018) 132 (Supplement 1): 4946.

https://doi.org/10.1182/blood-2018-99-117832

Published: 2018

Journal Articles

HIF1A Is a Critical Downstream Mediator for Hemophagocytic Lymphohistiocytosis

Blood (2017) 130 (Supplement 1): 3565.

https://doi.org/10.1182/blood.V130.Suppl_1.3565.3565

Published: 2017

Journal Articles

A Spic/BCLAF1 Complex Suppresses Pre-B Cell Receptor Signaling in Response to RAG-Mediated DNA Breaks

Deepti Soodgupta, PhD, Lynn S White, Jeffrey J Bednarski, MD PhD

Blood (2017) 130 (Supplement 1): 619.

https://doi.org/10.1182/blood.V130.Suppl_1.619.619

Published: 2017

Journal Articles

Determinants of Early Death and Outcomes for Acute Promyelocytic Leukemia in the Arsenic Era: A Real World Study

Honghu Zhu, Jinsong Jia, Jiang Qian, PhD, Hao Jiang, MD, Jin Lu, Bin Jiang, Xiaojun Huang

Blood (2017) 130 (Supplement 1): 1340.

https://doi.org/10.1182/blood.V130.Suppl_1.1340.1340

Published: 2017

Journal Articles

Upregulation of Alternatively Glycosylated Smoothened (SMO) Is Involved in Doxorubicin (DXR) Resistance in Diffuse Large B-Cell Lymphoma

Nitin Agarwal, PhD, Kranthi Kunkalla, MS, Sandra Sanchez, MD, Amineh Vaghefi, MD, Darius Juskevicius, PhD, Alexandar Tzankov, Ramiro E Verdun, PhD, Ralf Landgraf, PhD, Francisco Vega, MD PhD

Blood (2017) 130 (Supplement 1): 3839.

https://doi.org/10.1182/blood.V130.Suppl_1.3839.3839

Published: 2017

Journal Articles

Attenuated Protein Synthesis Drives the Hematopoietic Defects in Shwachman-Diamond Syndrome

Pekka Jaako, PhD, Chi C Wong, PhD MD, David Adams, PhD, Alan J. Warren, PhD FRCP, FRCPath

Blood (2017) 130 (Supplement 1): 876.

https://doi.org/10.1182/blood.V130.Suppl_1.876.876

Published: 2017

Journal Articles

BCL-2 Inhibition with ABT-199 Shows Efficacy in AML Cell Lines with Synergistic Effects upon Addition of the MEK Inhibitor GDC-0973 and Prolongs Survival in an NAS/BCL-2-Mediated Mouse Model of AML Post-MDS

Rose Ann Padua, PhD, Mathieu Chiquet, BSc, Qi Zhang, PhD MD, Claire Kappel, Patricia Krief, PhD, Niclas Setterblad, PhD, Dr Omidvar, BSc, MSc, PhD, Marina Konopleva, MD PhD, Michael Andreeff, MD PhD, Marika PLA, PhD, Lionel Ades, MD PhD, Pierre Fenaux, MD PhD, Christine Chomienne, MD PhD

Blood (2017) 130 (Supplement 1): 2613.

https://doi.org/10.1182/blood.V130.Suppl_1.2613.2613

Published: 2017

Journal Articles

High-Level EVI1 Perturbs Hematopoietic Function By Skewing Cells Towards Myeloid Phenotype Via Induction of PU.1/ Spi1 Â Transcription

Archibald S Perkins, MD PhD, Michael Wilson, PhD, Edward Ayoub, MS, Yi Zhang, PhD, McGrath E Kathleen, PhD, James Palis, MD, Allison J. Li, MS, Laura M. Calvi, MD

Blood (2017) 130 (Supplement 1): 2505.

https://doi.org/10.1182/blood.V130.Suppl_1.2505.2505

Published: 2017

Journal Articles

Targeting Systemic Inflammatory Response Syndrome As Initial Therapy and Oral Arsenic Based Consolidation Regimen for Acute Promyelocytic Leukemia

Stephen Yang Liang, MD

Blood (2017) 130 (Supplement 1): 1333.

https://doi.org/10.1182/blood.V130.Suppl_1.1333.1333

Published: 2017

Journal Articles

Paradoxical Enhancement of Leukemogenesis in Acute Myeloid Leukemia Cells with Moderately Attenuated RUNX1 Expressions

Kensho Suzuki, Ken Morita, MD, PhD, Shintaro Maeda, Hiroki Kiyose, Souichi Adachi, MD, PhD, Yasuhiko Kamikubo, MD, PhD

Blood (2016) 128 (22): 2710.

https://doi.org/10.1182/blood.V128.22.2710.2710

Published: 2016

NARROW

Spred1 Insufficiency in the Hematopoietic and/or Vascular Compartments of the Bone Marrow (BM) Niche Promotes Aggressive Leukemogenesis in Chronic Myelogenous Leukemia (CML)

A Functional Analysis of SNP on Anthracycline-Induced Cardiotoxicity in a Uniform Genetic Background Using CRISPR/Cas9 Mediated Single-Base-Edited iPSCs

Dual Targeting of Mitochondrial Unfolded Protein Response and BCL2 in Acute Myeloid Leukemia

Microrna-126 Levels Modulate B-ALL Aggressiveness but Require Tight Regulation to Guarantee Disease Maintenance

Platelet Protein Glycosylation in Immune Thrombocytopenia

MYC Functions As a Master Switch for Natural Killer Cell-Mediated Immune Surveillance of Lymphoid Malignancies

Genomic and Proteomic Profiling of AF10-Fusion Oncoproteins Reveal Mechanisms of Leukemogenesis and Actionable Targets

Targeting the Glyco-Antigen CD75s with the Tetravalent, Fc-Engineered Antibody 'Ebu-141 Tetra' Induces Potent Killing of B Cell Lymphoma and Plasma Cell Tumors

Inducible Correction of a RUNX1 Mutation of Human AML Causes a Switch of AML to B-ALL

Improved Pharmacokinetic Profile for BAY 81-8973 Due to Increased Branching and Sialylation of N-Linked Glycans of Recombinant Factor VIII

Repeated Transfusion of Granulocytes to Control Multidrug-Resistant Pseudomonas Aeruginosa Sepsis in Haploidentical Hematopoietic Stem Cell Transplant Patients during Pre-Engraftment Stage

HIF1A Is a Critical Downstream Mediator for Hemophagocytic Lymphohistiocytosis

A Spic/BCLAF1 Complex Suppresses Pre-B Cell Receptor Signaling in Response to RAG-Mediated DNA Breaks

Determinants of Early Death and Outcomes for Acute Promyelocytic Leukemia in the Arsenic Era: A Real World Study

Upregulation of Alternatively Glycosylated Smoothened (SMO) Is Involved in Doxorubicin (DXR) Resistance in Diffuse Large B-Cell Lymphoma

Attenuated Protein Synthesis Drives the Hematopoietic Defects in Shwachman-Diamond Syndrome

BCL-2 Inhibition with ABT-199 Shows Efficacy in AML Cell Lines with Synergistic Effects upon Addition of the MEK Inhibitor GDC-0973 and Prolongs Survival in an NAS/BCL-2-Mediated Mouse Model of AML Post-MDS

High-Level EVI1 Perturbs Hematopoietic Function By Skewing Cells Towards Myeloid Phenotype Via Induction of PU.1/ Spi1 Â Transcription

Targeting Systemic Inflammatory Response Syndrome As Initial Therapy and Oral Arsenic Based Consolidation Regimen for Acute Promyelocytic Leukemia

Paradoxical Enhancement of Leukemogenesis in Acute Myeloid Leukemia Cells with Moderately Attenuated RUNX1 Expressions

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American Society of Hematology

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ASH Publications

American Society of Hematology

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