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Journal Articles

FVIII Protein Is Not Detectable in Human PBMCs or Livers from Dogs with an Intron-22 Inversion Mutation: Implications for FVIII Immunogenicity and Tolerance

Devi Gunasekera, MBBS, Pooja Vir, PhD, Ahmad Faisal Karim, PhD, Margaret V. Ragni, MD MPH, Elizabeth P. Merricks, PhD, Timothy C. Nichols, MD, Kathleen P. Pratt, PhD

Blood (2019) 134 (Supplement_1): 630.

https://doi.org/10.1182/blood-2019-124880

Published: 2019

Journal Articles

Residues 1680-1684 in the A3 Domain of Factor VIII Contain a Novel Thrombin-Interactive Site Responsible for Proteolytic Cleavage at Arg 1689

Yuto Nakajima, MD, Keiji Nogami, MD PhD, Hiroaki Minami, MD, Kana Sasai, Midori Shima, MD PhD

Blood (2019) 134 (Supplement_1): 1107.

https://doi.org/10.1182/blood-2019-129313

Published: 2019

Journal Articles

Oryzocytosis: A Novel Morphological Variant of Hereditary Elliptocytosis Associated with a Novel Mutation in β-Spectrin ( SPTB c154 C>T p.Arg52Trp)

Alexander Glaros, MD, Manisha Gadgeel, MBBS, MS, Shruti Bagla, PhD, Steven Buck, MS, Roland Chu, MD, Yaddanapudi Ravindranath, MBBS, Brian Edwards, PhD, Asmita Vaishnav

Blood (2019) 134 (Supplement_1): 3509.

https://doi.org/10.1182/blood-2019-131219

Published: 2019

Journal Articles

Staurosporine Induces Caspase-Dependent Proteolysis of MEF2D-Fusion Protein and Cell Death Selective to MEF2D-Fusion-Positive ALL Cells

Naoyuki Tange, MD, Fumihiko Hayakawa, MD, PhD, Takahiko Yasuda, MD, PhD, Hideyuki Yamamoto, MD, Daiki Hirano, MD, PhD, Shinobu Tsuzuki, MD,PhD, Hitoshi Kiyoi, MD PhD

Blood (2019) 134 (Supplement_1): 1349.

https://doi.org/10.1182/blood-2019-123602

Published: 2019

Journal Articles

TFDP3 and DDX53 are Highly Re-Expressed after One Cycle of Azacitidine in Myelodysplastic Syndrome Patients Achieving Complete Response: A Cancer Testis Antigen RNA-Seq Screening

Ana M Hurtado López, Tzu Hua Chen-Liang, Joaquín Panadero, Eduardo José Salido, MD, Victor Beltrán, Begoña Muiña, Noelia Navarro-Villamor, Inés Calabria, Ana Isabel Antón, Francisco José Ortuño, Vicente Vicente, MD PhD, Andres Jerez

Blood (2018) 132 (Supplement 1): 4340.

https://doi.org/10.1182/blood-2018-99-117851

Published: 2018

Journal Articles

A Novel Variant of Factor VIII Yields Cofactor Activity without Proteolysis between the A1 and A2 Domains

Manjunath Goolyam Basavaraj, PhD, Sriram Krishnaswamy, PhD

Blood (2018) 132 (Supplement 1): 3771.

https://doi.org/10.1182/blood-2018-99-116267

Published: 2018

Journal Articles

Mechanism Underlying a Role for Factor XIII (FXIII) Polymorphism in Sickle Cell Disease-Associated Priapism

Marilyn J. Telen, MD, Milena Batchvarova, MS, Joan D Beckman, MD PhD, Martha Delahunty, PhD, Karen L Soldano, BS, Allison E Ashley-Koch, PhD, Alisa S. Wolberg, PhD

Blood (2018) 132 (Supplement 1): 2361.

https://doi.org/10.1182/blood-2018-99-116946

Published: 2018

Journal Articles

HMGB1 Interacts with the MLL-AF4 Fusion Complex to Regulate Pro-Leukemic Gene Transcription in Infant Acute Lymphoblastic Leukemia

Liana M Toia, BS, Erica Lynne Braverman, MD, Jinno Antonio Magno, MD, Jessica C. Shand, MD

Blood (2018) 132 (Supplement 1): 2602.

https://doi.org/10.1182/blood-2018-99-110833

Published: 2018

Journal Articles

Erythrocyte Cytochrome b Reductase 1 Protein Levels and Structure in Sickle Cell Patients

Richard Kulmacz, PhD, Hamidreza Farzaneh, MS, Kathryn L McElhinney, BS, Jose M. Rodriguez, BS, Nicole C. Thomason, BS, Ehsan Irajizad, BE, Vladimir Berka, PhD, Wen Liu, PhD, Modupe Idowu, MD, Harinder S. Juneja, MD

Blood (2018) 132 (Supplement 1): 3654.

https://doi.org/10.1182/blood-2018-99-119885

Published: 2018

Journal Articles

Contribution of Factor VIII A3 Domain Residues 1793-1795 to a Factor IXa-Interactive Site

Masahiro Takeyama, Keiji Nogami, MDPhD, Kana Sasai, Midori Shima, MD PhD

Blood (2018) 132 (Supplement 1): 1173.

https://doi.org/10.1182/blood-2018-99-113260

Published: 2018

Journal Articles

Cy7-Tocilizumab/Fab(Tocilizumab): Near Infrared Fluorescence In Vivo Imaging of Multiple Myeloma

Ximena Camacho, MSc, Carolina Perroni, Lic, Mara de Souza Junqueira, Marcelo Fernandez, Roger Chammas, Carlos Buchpiguel, Juan Pablo Gambini, Pablo Cabral, Eloisa Riva, MD

Blood (2018) 132 (Supplement 1): 5621.

https://doi.org/10.1182/blood-2018-99-114186

Published: 2018

Journal Articles

A Novel Mechanism of Factor VIIa/Tissue Factor (TF)-Catalyzed Activation and Inactivation of B-Domain-Deleted Factor VIII in the Early Initiation Phases of Coagulation

Yuto Nakajima, MD, Koji Yada, MD PhD, Keiji Nogami, MDPhD, Midori Shima, MD PhD

Blood (2018) 132 (Supplement 1): 1162.

https://doi.org/10.1182/blood-2018-99-115645

Published: 2018

Journal Articles

Quantitative Structural Characterization of Fibrinogen's αC Regions in Fibrin Monomers and Oligomers

Anna D. Protopopova, PhD, Rustem I. Litvinov, MD PhD, Dmitry V. Klinov, PhD, Dennis K. Galanakis, MD, John W. Weisel, PhD

Blood (2017) 130 (Supplement 1): 1056.

https://doi.org/10.1182/blood.V130.Suppl_1.1056.1056

Published: 2017

Journal Articles

Generation and Analysis of Genetically Modified CD14+ Monocytes with Dysferlin Overexpression

Irina Starostina, Valeriya Soloveva, PhD, Alisa Shaimardanova, Roman Deev, Arthur Isaev, Albert Rizvanov, DSc, PhD

Blood (2017) 130 (Supplement 1): 5565.

https://doi.org/10.1182/blood.V130.Suppl_1.5565.5565

Published: 2017

Journal Articles

Factor VIII Binds to an Acidic Fibrinogen Variant, a Critical Component of the High-Affinity Fibrin Binding Site, Resulting in Increased Cofactor Activity

Valerie Anne Novakovic, MS, Gary E Gilbert, MD

Blood (2017) 130 (Supplement 1): 1064.

https://doi.org/10.1182/blood.V130.Suppl_1.1064.1064

Published: 2017

Journal Articles

Pharmacokinetics of Subcutaneously Administered Simoctocog Alfa with Von Willebrand Factor Fragment Candidates in a Minipig Model

Barbara A Solecka-Witulska, PhD, Silvio Wuschko, PhD, Christoph Kannicht, PhD

Blood (2017) 130 (Supplement 1): 1073.

https://doi.org/10.1182/blood.V130.Suppl_1.1073.1073

Published: 2017

Journal Articles

Regulation of Factor VIII By Activated Protein C: Assessment In Vitro and In Vivo

Nicole A. Parsons, B.S., Michelle D. Ho, BS, Robert J. Davidson, BS, Nabil K. Thalji, PhDMD, Ben J. Samelson-Jones, MD PhD, Rodney M Camire, PhD, Lindsey A. George, MD

Blood (2017) 130 (Supplement 1): 3650.

https://doi.org/10.1182/blood.V130.Suppl_1.3650.3650

Published: 2017

Journal Articles

Apolipoprotein B-100 Binds Von Willebrand Factor and Accelerates Its Proteolysis By ADAMTS13 Under Fluidic Shear

Wenjing Cao, PhD, Jingzhi Li, PhD, X. Long Zheng, MD, PhD

Blood (2017) 130 (Supplement 1): 3653.

https://doi.org/10.1182/blood.V130.Suppl_1.3653.3653

Published: 2017

Journal Articles

Plasma Proteolytic Cascade Activation and Control during Neonatal Cardiopulmonary Bypass Surgery

Susan A. Maroney, DVM, PhD, Julie A. Peterson, PhD, Wes Zwifelhofer, BS, Rachel Bercovitz, MD MS, Ronald K. Woods, MD PhD, Alan E. Mast, MDPhD

Blood (2017) 130 (Supplement 1): 2356.

https://doi.org/10.1182/blood.V130.Suppl_1.2356.2356

Published: 2017

Journal Articles

Comparison of the Functional Characteristics and Post-Translational Modifications of Commercial Factor VIII Products

Guido Kohla, PhD, Larisa Belyanskaya, PhD, Maya Tiemeyer, PhD, Thole Züchner, PhD, Irena Knappik, PhD, Julia Rosenlöcher, PhD

Blood (2017) 130 (Supplement 1): 2362.

https://doi.org/10.1182/blood.V130.Suppl_1.2362.2362

Published: 2017

NARROW

FVIII Protein Is Not Detectable in Human PBMCs or Livers from Dogs with an Intron-22 Inversion Mutation: Implications for FVIII Immunogenicity and Tolerance

Residues 1680-1684 in the A3 Domain of Factor VIII Contain a Novel Thrombin-Interactive Site Responsible for Proteolytic Cleavage at Arg 1689

Oryzocytosis: A Novel Morphological Variant of Hereditary Elliptocytosis Associated with a Novel Mutation in β-Spectrin ( SPTB c154 C>T p.Arg52Trp)

Staurosporine Induces Caspase-Dependent Proteolysis of MEF2D-Fusion Protein and Cell Death Selective to MEF2D-Fusion-Positive ALL Cells

TFDP3 and DDX53 are Highly Re-Expressed after One Cycle of Azacitidine in Myelodysplastic Syndrome Patients Achieving Complete Response: A Cancer Testis Antigen RNA-Seq Screening

A Novel Variant of Factor VIII Yields Cofactor Activity without Proteolysis between the A1 and A2 Domains

Mechanism Underlying a Role for Factor XIII (FXIII) Polymorphism in Sickle Cell Disease-Associated Priapism

HMGB1 Interacts with the MLL-AF4 Fusion Complex to Regulate Pro-Leukemic Gene Transcription in Infant Acute Lymphoblastic Leukemia

Erythrocyte Cytochrome b Reductase 1 Protein Levels and Structure in Sickle Cell Patients

Contribution of Factor VIII A3 Domain Residues 1793-1795 to a Factor IXa-Interactive Site

Cy7-Tocilizumab/Fab(Tocilizumab): Near Infrared Fluorescence In Vivo Imaging of Multiple Myeloma

A Novel Mechanism of Factor VIIa/Tissue Factor (TF)-Catalyzed Activation and Inactivation of B-Domain-Deleted Factor VIII in the Early Initiation Phases of Coagulation

Quantitative Structural Characterization of Fibrinogen's αC Regions in Fibrin Monomers and Oligomers

Generation and Analysis of Genetically Modified CD14+ Monocytes with Dysferlin Overexpression

Factor VIII Binds to an Acidic Fibrinogen Variant, a Critical Component of the High-Affinity Fibrin Binding Site, Resulting in Increased Cofactor Activity

Pharmacokinetics of Subcutaneously Administered Simoctocog Alfa with Von Willebrand Factor Fragment Candidates in a Minipig Model

Regulation of Factor VIII By Activated Protein C: Assessment In Vitro and In Vivo

Apolipoprotein B-100 Binds Von Willebrand Factor and Accelerates Its Proteolysis By ADAMTS13 Under Fluidic Shear

Plasma Proteolytic Cascade Activation and Control during Neonatal Cardiopulmonary Bypass Surgery

Comparison of the Functional Characteristics and Post-Translational Modifications of Commercial Factor VIII Products

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American Society of Hematology

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American Society of Hematology

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