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Journal Articles

The Ribonucleotide Reductase Inhibitor, Didox, Reduces the In Vivo Vascular Inflammation and Oxidative Stress Induced By Acute Hemolysis

Nicola Conran, PhD, Juliete A.F. Silva, PhD, Erica M.F. Gotardo, PhD, Hanan Chweih, M.Sc., Lediana I. Miguel, M.Sc., Flávia Costa Leonardo, PhD, Wilson A. Ferreira, Jr., PhD, Bo E. Hedlund, PhD, Howard L. Elford, PhD, Fernando F. Costa, MD, PhD

Blood (2018) 132 (Supplement 1): 1034.

https://doi.org/10.1182/blood-2018-99-119224

Published: 2018

Journal Articles

Interim Analysis of the Myeloproliferative Disorders Research Consortium (MPD-RC) 112 Global Phase III Trial of Front Line Pegylated Interferon Alpha-2a Vs. Hydroxyurea in High Risk Polycythemia Vera and Essential Thrombocythemia

John O. Mascarenhas, MD MS, Josef T. Prchal, MD, Alessandro Rambaldi, MD, Ruben A. Mesa, MD, Dmitriy Berenzon, MD, Abdulraheem Yacoub, MD, Claire N. Harrison, DM, FRCP, FRCPath, Mary Frances McMullin, MD, Alessandro M. Vannucchi, MD PhD, Joanne C Ewing, PhD BMBS, BSc, FRPATH,, Casey L O'Connell, MD, Jean-Jacques Kiladjian, MD PhD, Adam Mead, MD PhD, Elliott F. Winton, MD, David S. Leibowitz, MD, Valerio De Stefano, Murat O. Arcasoy, MD, Craig M. Kessler, MD, Rosalind Catchatorian, Damiano Rondelli, MD, Richard T. Silver, MD, Ellen K. Ritchie, MD, Arnon Nagler, Marina Kremyanskaya, MD PhD, Richard F. Schlenk, MD, Rona Singer Weinberg, PhD, Mohamed E Salama, MD, Gianni Tognoni, Giuseppe Prosperini, Alessandra Di Lelio, Eliseo Serone, Lorenzo Marfisi, Jill Kleczko, Heidi E. Kosiorek, MS, Tiziano Barbui, MD, Amylou C. Dueck, PhD, Ronald Hoffman, MD

Blood (2016) 128 (22): 479.

https://doi.org/10.1182/blood.V128.22.479.479

Published: 2016

Journal Articles

The Novel Ribonucleotide Reductase Inhibitor Didox Is Active Against AML with Limited Toxicities

Guerry J Cook, MSc, David L. Caudell, DVM, PhD, Howard L Elford, PhD, Timothy Pardee, MD, PhD

Blood (2012) 120 (21): 1513.

https://doi.org/10.1182/blood.V120.21.1513.1513

Published: 2012

Journal Articles

Metabolic Profiling in Sickle Cell Disease

Borys Hrinczenko, MD, PhD

Blood (2011) 118 (21): 4837.

https://doi.org/10.1182/blood.V118.21.4837.4837

Published: 2011

Journal Articles

Activity of the Novel Ribonucleotide Reductase Inhibitor Didox on Human and Murine Models of Acute Leukemia,

Guerry J Cook, MSc, Howard L Elford, PhD, Timothy Pardee, MD, PhD

Blood (2011) 118 (21): 3637.

https://doi.org/10.1182/blood.V118.21.3637.3637

Published: 2011

Journal Articles

Treatment of Gamma-Herpes Virus Associated Lymphomas with Lytic-Inducing Agents.

Lydia Fein, Ngoc L Toomey, Dirk P Dittmer, Ph.D, Juan Carlos Ramos, MD

Blood (2009) 114 (22): 4786.

https://doi.org/10.1182/blood.V114.22.4786.4786

Published: 2009

Journal Articles

Didox Induced Apoptosis Occurs by Inhibiting DNA Synthesis and Repair Via Down-Regulation of Ribonucleotide Reductase M1 in Multiple Myeloma (MM).

Noopur Raje, MD, Shaji Kumar, MD, Teru Hideshima, MD, PhD, Kenji Ishitsuka, MD, Hiroshi Yasui, MD, PhD, Norihiko Shiraishi, PhD, Tanyel Kiziltepe, PhD, Shweta Chhetri, BS, Nikhil C. Munshi, MD, Kenneth C. Anderson, MD

Blood (2005) 106 (11): 5153.

https://doi.org/10.1182/blood.V106.11.5153.5153

Published: 2005

Journal Articles

Daunorubicin, Cytarabine and Fludarabine (DAF) for the Treatment of Relapsed/Refractory Acute Myeloid Leukemia. Phase II Study by the Polish Adult Leukemia Group (PALG).

Jerzy Holowiecki, Sebastian Grosicki, MD, Slawomira Krzemien, MD, Aleksander Skotnicki, Krzysztof Warzecha, Barbara Zdziarska, MD, Beata Stella-Holowiecka, MD, Malgorzata Krawczyk-Kulis, MD, Malgorzata Kopera, MD, Maria Wojciechowska, MD

Blood (2004) 104 (11): 4507.

https://doi.org/10.1182/blood.V104.11.4507.4507

Published: 2004

Journal Articles

Induction of Apoptosis by Didox Via Down-Regulation of Bcl-2 Family Proteins in Multiple Myeloma (MM).

Noopur Raje, MD, Shaji Kumar, MD, Teru Hideshima, MD, PhD, Kenji Ishitsuka, MD, Aldo Roccaro, MD, Hiroshi Yasui, MD, Makoto Hamasaki, MD, Norihiko Shiraisi, PhD, Nikhil C. Munshi, MD, Howard Elford, PhD, Kenneth C. Anderson, MD

Blood (2004) 104 (11): 4842.

https://doi.org/10.1182/blood.V104.11.4842.4842

Published: 2004

NARROW

The Ribonucleotide Reductase Inhibitor, Didox, Reduces the In Vivo Vascular Inflammation and Oxidative Stress Induced By Acute Hemolysis

Interim Analysis of the Myeloproliferative Disorders Research Consortium (MPD-RC) 112 Global Phase III Trial of Front Line Pegylated Interferon Alpha-2a Vs. Hydroxyurea in High Risk Polycythemia Vera and Essential Thrombocythemia

The Novel Ribonucleotide Reductase Inhibitor Didox Is Active Against AML with Limited Toxicities

Metabolic Profiling in Sickle Cell Disease

Activity of the Novel Ribonucleotide Reductase Inhibitor Didox on Human and Murine Models of Acute Leukemia,

Treatment of Gamma-Herpes Virus Associated Lymphomas with Lytic-Inducing Agents.

Didox Induced Apoptosis Occurs by Inhibiting DNA Synthesis and Repair Via Down-Regulation of Ribonucleotide Reductase M1 in Multiple Myeloma (MM).

Daunorubicin, Cytarabine and Fludarabine (DAF) for the Treatment of Relapsed/Refractory Acute Myeloid Leukemia. Phase II Study by the Polish Adult Leukemia Group (PALG).

Induction of Apoptosis by Didox Via Down-Regulation of Bcl-2 Family Proteins in Multiple Myeloma (MM).

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American Society of Hematology

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ASH Publications

American Society of Hematology

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