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Journal Articles

Metformin Suppresses Expression of Pre-Fibrotic Enzyme Lysyl-Oxidase Levels through Inhibition of UPR in MPN Cells

Megumi Suzuki, MD, Ichiro Kawashima, Keita Kirito, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3070.
https://doi.org/10.1182/blood-2018-99-113276
Published: 2018
Journal Articles

Regulation of Lysyl Oxidase, a Key Regulator of Bone Marrow Fibrosis, in Myelofibrosis

Orly Leiva, BS, Alan B. Cantor, MD, PhD, Philip Trackman, PhD, Katya Ravid, PhD DSc
Journal: Blood
Blood (2017) 130 (Supplement 1): 1662.
https://doi.org/10.1182/blood.V130.Suppl_1.1662.1662
Published: 2017
Journal Articles

A Novel Lysyl Oxidase Inhibitor Attenuates Bone Marrow Fibrosis and Decreases Spleen Size in a Mouse Model of Primary Myelofibrosis

Orly Leiva, BS, Shinobu Matsuura, DVM,PhD, Alison Findlay, Craig Turner, Wolfgang Jarolimek, Katya Ravid, PhD DSc
Journal: Blood
Blood (2017) 130 (Supplement 1): 4214.
https://doi.org/10.1182/blood.V130.Suppl_1.4214.4214
Published: 2017
Journal Articles

Upregulation of lysyl oxidase and adhesion to collagen of human megakaryocytes and platelets in primary myelofibrosis

Vittorio Abbonante, Vipul Chitalia, Vittorio Rosti, Orly Leiva, Shinobu Matsuura, Alessandra Balduini, Katya Ravid
Journal: Blood
Blood (2017) 130 (6): 829–831.
https://doi.org/10.1182/blood-2017-04-777417
Published: 2017
Includes: Supplemental data
Journal Articles

JAK2V617F - Positive Endothelial Cells Display Pro-Thrombotic Characteristics

Anna Guadall, PhD, Elodie Lesteven, PharmD, PhD, Gil Letort, Sarah Awan Toor, Doriane Pognant, Megane Brusson, Emmanuelle Verger, PhD, Jerome Larghero, PharmD, PhD, Valerie Vanneaux, PharmD, PhD, Christine Chomienne, MD PhD, Wassim El Nemer, PhD, Bruno Cassinat, PharmD, PhD, Jean-Jacques Kiladjian, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4273.
https://doi.org/10.1182/blood.V128.22.4273.4273
Published: 2016
Journal Articles

A Newly Identified Platelet and Megakaryocyte Lysyl Oxidase-Adhesion to Collagen Axis in Human Primary Myelofibrosis

Alessandra Balduini, MD, Vittorio Abbonante, PhD, Shinobu Matsuura, DVM, PhD, Vittorio Rosti, Katya Ravid, PhD DSc
Journal: Blood
Blood (2016) 128 (22): 3133.
https://doi.org/10.1182/blood.V128.22.3133.3133
Published: 2016
Journal Articles

Emerging Potential Roles of Lysyl-Oxidase-like 2 Stimulates Cancer Associated Fibroblasts Promoting Myelofibrosis of Myeloproliferative Neoplasms

Xiaoli Liu, PhD, Na Xu, MD, Chengyun Pan, MD, Xuan Zhou, MD, Qifa Liu, Ru Feng, Jing Sun, Hongsheng Zhou
Journal: Blood
Blood (2016) 128 (22): 5495.
https://doi.org/10.1182/blood.V128.22.5495.5495
Published: 2016
Journal Articles

Lysyl oxidase is associated with increased thrombosis and platelet reactivity

Shinobu Matsuura, Rongjuan Mi, Milka Koupenova, Alexia Eliades, Shenia Patterson, Paul Toselli, Jonathan Thon, Joseph E. Italiano, Jr, Philip C. Trackman, Nikolaos Papadantonakis, Katya Ravid
Journal: Blood
Blood (2016) 127 (11): 1493–1501.
https://doi.org/10.1182/blood-2015-02-629667
Published: 2016
Includes: Supplemental data
Journal Articles

Decitabine Induced the Cell Differentiation, Decreased Malignant Potential, and Increased Susceptibility to Apoptosis Via a Death Receptor Pathway with Hypomethylation of MS4A3, PAR-4, APITD1, LOX in Myelodysplastic Syndrome Cell Line, MDS-L

Rie Nishi, Takahiro Yamauchi, MD PhD, Miyuki Ookura, MD, Yasufumi Matsuda, MD, Toshiki Tasaki, MD, Kaoru Tohyama, MD PhD, Takanori Ueda, MD PhD
Journal: Blood
Blood (2014) 124 (21): 4599.
https://doi.org/10.1182/blood.V124.21.4599.4599
Published: 2014
Journal Articles

Megakaryocyte pathology and bone marrow fibrosis: the lysyl oxidase connection

Nikolaos Papadantonakis, Shinobu Matsuura, Katya Ravid
Journal: Blood
Blood (2012) 120 (9): 1774–1781.
https://doi.org/10.1182/blood-2012-02-402594
Published: 2012
Journal Articles

Transforming Growth Factor β (TGF-β)- and P-Selectin-Dependent Fibroblast Peripolesis of Megakaryocytes Contributes to Development of Myelofibrosis in Gata1 low mice

Fabrizio Martelli, Maria Zingariello, Barbara Ghinassi, Fiorella Ciaffoni, Rosa Alba Rana, Anna Rita F Migliaccio, PhD
Journal: Blood
Blood (2011) 118 (21): 1741.
https://doi.org/10.1182/blood.V118.21.1741.1741
Published: 2011
Journal Articles

Lysyl oxidase-like protein-2 regulates sprouting angiogenesis and type IV collagen assembly in the endothelial basement membrane

Marine Bignon, Cathy Pichol-Thievend, Julie Hardouin, Marilyne Malbouyres, Nicolas Bréchot, Luiz Nasciutti, Alain Barret, Jérémie Teillon, Emilie Guillon, Eric Etienne, Michel Caron, Raymonde Joubert-Caron, Catherine Monnot, Florence Ruggiero, Laurent Muller, Stéphane Germain
Journal: Blood
Blood (2011) 118 (14): 3979–3989.
https://doi.org/10.1182/blood-2010-10-313296
Published: 2011
Includes: Multimedia, Supplemental data
Journal Articles

Vascular balancing act: EGFL7 and Notch

George E. Davis
Journal: Blood
Blood (2010) 116 (26): 5791–5793.
https://doi.org/10.1182/blood-2010-11-314500
Published: 2010