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Journal Articles

Metformin Suppresses Expression of Pre-Fibrotic Enzyme Lysyl-Oxidase Levels through Inhibition of UPR in MPN Cells

Megumi Suzuki, MD, Ichiro Kawashima, Keita Kirito, MD

Blood (2018) 132 (Supplement 1): 3070.

https://doi.org/10.1182/blood-2018-99-113276

Published: 2018

Journal Articles

Regulation of Lysyl Oxidase, a Key Regulator of Bone Marrow Fibrosis, in Myelofibrosis

Orly Leiva, BS, Alan B. Cantor, MD, PhD, Philip Trackman, PhD, Katya Ravid, PhD DSc

Blood (2017) 130 (Supplement 1): 1662.

https://doi.org/10.1182/blood.V130.Suppl_1.1662.1662

Published: 2017

Journal Articles

A Novel Lysyl Oxidase Inhibitor Attenuates Bone Marrow Fibrosis and Decreases Spleen Size in a Mouse Model of Primary Myelofibrosis

Orly Leiva, BS, Shinobu Matsuura, DVM,PhD, Alison Findlay, Craig Turner, Wolfgang Jarolimek, Katya Ravid, PhD DSc

Blood (2017) 130 (Supplement 1): 4214.

https://doi.org/10.1182/blood.V130.Suppl_1.4214.4214

Published: 2017

Journal Articles

Upregulation of lysyl oxidase and adhesion to collagen of human megakaryocytes and platelets in primary myelofibrosis

Vittorio Abbonante, Vipul Chitalia, Vittorio Rosti, Orly Leiva, Shinobu Matsuura, Alessandra Balduini, Katya Ravid

Blood (2017) 130 (6): 829–831.

https://doi.org/10.1182/blood-2017-04-777417

Published: 2017

Includes: Supplemental data

Journal Articles

A Newly Identified Platelet and Megakaryocyte Lysyl Oxidase-Adhesion to Collagen Axis in Human Primary Myelofibrosis

Alessandra Balduini, MD, Vittorio Abbonante, PhD, Shinobu Matsuura, DVM, PhD, Vittorio Rosti, Katya Ravid, PhD DSc

Blood (2016) 128 (22): 3133.

https://doi.org/10.1182/blood.V128.22.3133.3133

Published: 2016

Journal Articles

Emerging Potential Roles of Lysyl-Oxidase-like 2 Stimulates Cancer Associated Fibroblasts Promoting Myelofibrosis of Myeloproliferative Neoplasms

Xiaoli Liu, PhD, Na Xu, MD, Chengyun Pan, MD, Xuan Zhou, MD, Qifa Liu, Ru Feng, Jing Sun, Hongsheng Zhou

Blood (2016) 128 (22): 5495.

https://doi.org/10.1182/blood.V128.22.5495.5495

Published: 2016

Journal Articles

JAK2V617F - Positive Endothelial Cells Display Pro-Thrombotic Characteristics

Anna Guadall, PhD, Elodie Lesteven, PharmD, PhD, Gil Letort, Sarah Awan Toor, Doriane Pognant, Megane Brusson, Emmanuelle Verger, PhD, Jerome Larghero, PharmD, PhD, Valerie Vanneaux, PharmD, PhD, Christine Chomienne, MD PhD, Wassim El Nemer, PhD, Bruno Cassinat, PharmD, PhD, Jean-Jacques Kiladjian, MD PhD

Blood (2016) 128 (22): 4273.

https://doi.org/10.1182/blood.V128.22.4273.4273

Published: 2016

Journal Articles

Lysyl oxidase is associated with increased thrombosis and platelet reactivity

Shinobu Matsuura, Rongjuan Mi, Milka Koupenova, Alexia Eliades, Shenia Patterson, Paul Toselli, Jonathan Thon, Joseph E. Italiano, Jr, Philip C. Trackman, Nikolaos Papadantonakis, Katya Ravid

Blood (2016) 127 (11): 1493–1501.

https://doi.org/10.1182/blood-2015-02-629667

Published: 2016

Includes: Supplemental data

Journal Articles

Decitabine Induced the Cell Differentiation, Decreased Malignant Potential, and Increased Susceptibility to Apoptosis Via a Death Receptor Pathway with Hypomethylation of MS4A3, PAR-4, APITD1, LOX in Myelodysplastic Syndrome Cell Line, MDS-L

Rie Nishi, Takahiro Yamauchi, MD PhD, Miyuki Ookura, MD, Yasufumi Matsuda, MD, Toshiki Tasaki, MD, Kaoru Tohyama, MD PhD, Takanori Ueda, MD PhD

Blood (2014) 124 (21): 4599.

https://doi.org/10.1182/blood.V124.21.4599.4599

Published: 2014

Journal Articles

Megakaryocyte pathology and bone marrow fibrosis: the lysyl oxidase connection

Nikolaos Papadantonakis, Shinobu Matsuura, Katya Ravid

Blood (2012) 120 (9): 1774–1781.

https://doi.org/10.1182/blood-2012-02-402594

Published: 2012

Journal Articles

Transforming Growth Factor β (TGF-β)- and P-Selectin-Dependent Fibroblast Peripolesis of Megakaryocytes Contributes to Development of Myelofibrosis in Gata1 low mice

Fabrizio Martelli, Maria Zingariello, Barbara Ghinassi, Fiorella Ciaffoni, Rosa Alba Rana, Anna Rita F Migliaccio, PhD

Blood (2011) 118 (21): 1741.

https://doi.org/10.1182/blood.V118.21.1741.1741

Published: 2011

Journal Articles

Lysyl oxidase-like protein-2 regulates sprouting angiogenesis and type IV collagen assembly in the endothelial basement membrane

Marine Bignon, Cathy Pichol-Thievend, Julie Hardouin, Marilyne Malbouyres, Nicolas Bréchot, Luiz Nasciutti, Alain Barret, Jérémie Teillon, Emilie Guillon, Eric Etienne, Michel Caron, Raymonde Joubert-Caron, Catherine Monnot, Florence Ruggiero, Laurent Muller, Stéphane Germain

Blood (2011) 118 (14): 3979–3989.

https://doi.org/10.1182/blood-2010-10-313296

Published: 2011

Includes: Multimedia, Supplemental data

Journal Articles

Vascular balancing act: EGFL7 and Notch

George E. Davis

Blood (2010) 116 (26): 5791–5793.

https://doi.org/10.1182/blood-2010-11-314500

Published: 2010

NARROW

Metformin Suppresses Expression of Pre-Fibrotic Enzyme Lysyl-Oxidase Levels through Inhibition of UPR in MPN Cells

Regulation of Lysyl Oxidase, a Key Regulator of Bone Marrow Fibrosis, in Myelofibrosis

A Novel Lysyl Oxidase Inhibitor Attenuates Bone Marrow Fibrosis and Decreases Spleen Size in a Mouse Model of Primary Myelofibrosis

Upregulation of lysyl oxidase and adhesion to collagen of human megakaryocytes and platelets in primary myelofibrosis

A Newly Identified Platelet and Megakaryocyte Lysyl Oxidase-Adhesion to Collagen Axis in Human Primary Myelofibrosis

Emerging Potential Roles of Lysyl-Oxidase-like 2 Stimulates Cancer Associated Fibroblasts Promoting Myelofibrosis of Myeloproliferative Neoplasms

JAK2V617F - Positive Endothelial Cells Display Pro-Thrombotic Characteristics

Lysyl oxidase is associated with increased thrombosis and platelet reactivity

Decitabine Induced the Cell Differentiation, Decreased Malignant Potential, and Increased Susceptibility to Apoptosis Via a Death Receptor Pathway with Hypomethylation of MS4A3, PAR-4, APITD1, LOX in Myelodysplastic Syndrome Cell Line, MDS-L

Megakaryocyte pathology and bone marrow fibrosis: the lysyl oxidase connection

Transforming Growth Factor β (TGF-β)- and P-Selectin-Dependent Fibroblast Peripolesis of Megakaryocytes Contributes to Development of Myelofibrosis in Gata1 low mice

Lysyl oxidase-like protein-2 regulates sprouting angiogenesis and type IV collagen assembly in the endothelial basement membrane

Vascular balancing act: EGFL7 and Notch

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American Society of Hematology

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American Society of Hematology

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