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Journal Articles

Severely Impaired Platelet Function Due to a Novel Mutation of P2Y12 from a Human Subject with No History of Bleeding

John C Kostyak, PhD, Carol A Dangelmaier, BS, Benjamin R Mauri, BS, Akruti Patel, MSc, Satya P. Kunapuli, PhD

Blood (2018) 132 (Supplement 1): 1130.

https://doi.org/10.1182/blood-2018-99-113015

Published: 2018

Journal Articles

Novel role of prostate apoptosis response-4 tumor suppressor in B-cell chronic lymphocytic leukemia

Mary K. McKenna, Sunil K. Noothi, Sara S. Alhakeem, Karine Z. Oben, Joseph T. Greene, Rajeswaran Mani, Kathryn L. Perry, James P. Collard, Jacqueline R. Rivas, Gerhard C. Hildebrandt, Roger A. Fleischman, Eric B. Durbin, John C. Byrd, Chi Wang, Natarajan Muthusamy, Vivek M. Rangnekar, Subbarao Bondada

Blood (2018) 131 (26): 2943–2954.

https://doi.org/10.1182/blood-2017-10-813931

Published: 2018

Includes: Supplemental data

Journal Articles

Platelet-Based Factor VIII Activity Is Inhibited By Anti-C2 Domain Antibodies That Donâ€™t Significantly Inhibit Factor VIII Activity in a Standard Assay

Madhumouli Chatterjee, PhD, Shannon L. Meeks, MD, Valerie Anne Novakovic, MS, John S. Lollar, MD, Gary E Gilbert, MD

Blood (2017) 130 (Supplement 1): 2345.

https://doi.org/10.1182/blood.V130.Suppl_1.2345.2345

Published: 2017

Journal Articles

Preferential Inhibition of Fibrin Mediated Thrombosis in Rodent Models By JNJ-9375, a Novel exosite1 Thrombin Inhibitor

Madhu Chintala, PhD, Qiu Li, BS, Zheng Huang Devine, PhD, Matthew Bunce, PhD

Blood (2017) 130 (Supplement 1): 3712.

https://doi.org/10.1182/blood.V130.Suppl_1.3712.3712

Published: 2017

Journal Articles

Improved Inhibition of Protease-Activated Receptor 4 (PAR4) with Function-Blocking Antibodies Provides Equivalent Antithrombotic Activity in the Face of the Hyper-Reactive Thr120 PAR4 Variant

Shauna L French, Claudia Thalmann, Kellie Machlus, PhD, Mark A Sleeman, Justin R Hamilton, PhD

Blood (2017) 130 (Supplement 1): 3603.

https://doi.org/10.1182/blood.V130.Suppl_1.3603.3603

Published: 2017

Journal Articles

Phosphorylation of Y311 on Pkcδ Regulates Protease Activated Receptor 4-Mediated Signaling in Platelets

John Kostyak, PhD, Akruti Patel, MSc, Haritha G Reddy, BS, Carol A Dangelmaier, BS, Satya P. Kunapuli, PhD

Blood (2017) 130 (Supplement 1): 3604.

https://doi.org/10.1182/blood.V130.Suppl_1.3604.3604

Published: 2017

Journal Articles

Expression of Functional Human Proteinase Activated Receptor (PAR)-1 on Mouse Platelets

Alessandro Zarpellon, PhD, Taisuke Kanaji, MD, Sachiko Kanaji, MD PhD, Yosuke Morodomi, MD PhD, Zaverio M. Ruggeri, MD

Blood (2017) 130 (Supplement 1): 451.

https://doi.org/10.1182/blood.V130.Suppl_1.451.451

Published: 2017

Journal Articles

Par-4 Overexpression Impedes Leukemogenesis in the Eµ-TCL1 Leukemia Model

Joseph Thomas Greene, BS, Rahul Ramaswamy, Mary K McKenna, BS, Rajeswaran Mani, DVM,PhD, Frank Frissora, MS, Ronni Wasmuth, BS, Minh Tran, BS, Xiaokui Mo, PhD MAS, Carlo M. Croce, MD, Vivek Rangnekar, PhD, John C. Byrd, MD, Subbarao Bondada, PhD, Natarajan Muthusamy, DVM,PhD

Blood (2017) 130 (Supplement 1): 1223.

https://doi.org/10.1182/blood.V130.Suppl_1.1223.1223

Published: 2017

Journal Articles

PCTP (Phosphatidylcholine Transfer Protein) is Regulated By RUNX1 in Platelets/Megakaryocytes and is Associated with Adverse Cardiovascular Events

Natthapol Songdej, MD MPH, Guangfen Mao, MD, Deepak Voora, MD, Lawrence E. Goldfinger, PhD, Fabiola Del Carpio-Cano, Rachel Myers, Angara Koneti Rao, MBBS

Blood (2016) 128 (22): 365.

https://doi.org/10.1182/blood.V128.22.365.365

Published: 2016

Journal Articles

Platelet Membranes and Activation Pathway Determine Inhibitory Activity of Anti-Factor VIII C2 Domain Antibodies

Madhumouli Chatterjee, PhD, Shannon L. Meeks, MD, Valerie Anne Novakovic, MS, Pete Lollar, MD, Gary E. Gilbert, MD

Blood (2016) 128 (22): 2567.

https://doi.org/10.1182/blood.V128.22.2567.2567

Published: 2016

Journal Articles

Identification of Kinase-Dependent Signaling Pathways Regulated By Rap1b in Murine Platelets

Luis Paniagua, Xiaogang Wu, PhD, Michael Pereckas, Kathleen Noon, Gilbert White, II, MD

Blood (2016) 128 (22): 3717.

https://doi.org/10.1182/blood.V128.22.3717.3717

Published: 2016

Journal Articles

Role of Prostate Apoptosis Response-4 Tumor Suppressor in the Survival and Growth of Chronic Lymphocytic Leukemia

Sunil K Nooti, PhD, Mary K McKenna, B.S., Frank W Frissora, M.S., Beth W Gachuki, M.S., Sara S Alhakeem, M.S., Joseph T Greene, M.S., Natarajan Muthusamy, DVM, PhD, Vivek M Rangnekar, PhD, Subbarao Bondada, PhD

Blood (2015) 126 (23): 1731.

https://doi.org/10.1182/blood.V126.23.1731.1731

Published: 2015

Journal Articles

Transcription Factor RUNX1 Regulates Pctp (Phosphatidylcholine Transfer Protein) in Platelets: A Potential Role in Regulating Platelet Function

Natthapol Songdej, MD MPH, Guangfen Mao, MD, Lawrence E. Goldfinger, PhD, Angara Koneti Rao, MD

Blood (2015) 126 (23): 2247.

https://doi.org/10.1182/blood.V126.23.2247.2247

Published: 2015

Journal Articles

Thrombin Induces Protease Activated Receptor (PAR)-3/-4 Interaction in Human Podocytes

Sharma Ruchika, MD, Amanda P Waller, PhD, Shipra Agrawal, PhD, Berend H Isermann, MD, William E Smoyer, MD, Marvin T Nieman, PhD, Bryce A. Kerlin, MD

Blood (2015) 126 (23): 3488.

https://doi.org/10.1182/blood.V126.23.3488.3488

Published: 2015

Journal Articles

Parstatin Mediates Platelet Activation That Is Unaffected By PAR Antagonism

Paige Selvy Dunphy, PhD, Jayaprakash Kotha, PhD MBBS, Mason L. A. Dixon, BS, Jay M. Jalenak, BS, Lisa K. Jennings, PhD

Blood (2015) 126 (23): 2234.

https://doi.org/10.1182/blood.V126.23.2234.2234

Published: 2015

Journal Articles

Platelets and protease-activated receptor-4 contribute to acetaminophen-induced liver injury in mice

Kazuhisa Miyakawa, Nikita Joshi, Bradley P. Sullivan, Ryan Albee, Christina Brandenberger, Hartmut Jaeschke, Mitchell R. McGill, Michael A. Scott, Patricia E. Ganey, James P. Luyendyk, Robert A. Roth

Blood (2015) 126 (15): 1835–1843.

https://doi.org/10.1182/blood-2014-09-598656

Published: 2015

Includes: Supplemental data

Journal Articles

Distinct Genetic Loci Are Associated with Platelet Aggregation Responses to Collagen and Collagen Synthetic Related Peptide (SRP) in Mice

Hayley R Waterman, Peter C Thomson, PhD, Jill M Johnsen, MD, James D Gorham, MD PhD, Matthew S Ranson, James C. Zimring, MD PhD, Adam D. Munday, PhD

Blood (2014) 124 (21): 4165.

https://doi.org/10.1182/blood.V124.21.4165.4165

Published: 2014

Journal Articles

A Novel F2RL3 Variant Predicting a Tyr157Cys Substitution in Protease-Activated Receptor 4 Is Associated with Reduced Receptor Function in Platelets

Jane E Norman, Margaret R Cunningham, Matthew L Jones, Sarah K Westbury, Mary Walker, Stuart J Mundell, Andrew D Mumford

Blood (2014) 124 (21): 4149.

https://doi.org/10.1182/blood.V124.21.4149.4149

Published: 2014

Journal Articles

Impaired Hemostasis Caused By Deficit of Tissue Factor-Triggered Blood Coagulation Leads to Alveolar Hemorrhages and Increased Mortality in Influenza A Infection

Kohei Tatsumi, MD,PhD, Silvio Antoniak, PhD, Justin Milner, Melinda Beck, PhD, Nigel Mackman, PhD

Blood (2014) 124 (21): 2805.

https://doi.org/10.1182/blood.V124.21.2805.2805

Published: 2014

Journal Articles

Thrombin Induces Apoptosis in Human and Rat Podocytes in a Protease Activated Receptor (PAR)-Dependent Manner

Ruchika Sharma, MD, Amanda P Waller, PhD, Adam Guess, Shipra Agrawal, PhD, Berend Isermann, William E. Smoyer, MD, Marvin T. Nieman, PhD, Bryce A. Kerlin, MD

Blood (2014) 124 (21): 2808.

https://doi.org/10.1182/blood.V124.21.2808.2808

Published: 2014

NARROW

Severely Impaired Platelet Function Due to a Novel Mutation of P2Y12 from a Human Subject with No History of Bleeding

Novel role of prostate apoptosis response-4 tumor suppressor in B-cell chronic lymphocytic leukemia

Platelet-Based Factor VIII Activity Is Inhibited By Anti-C2 Domain Antibodies That Donâ€™t Significantly Inhibit Factor VIII Activity in a Standard Assay

Preferential Inhibition of Fibrin Mediated Thrombosis in Rodent Models By JNJ-9375, a Novel exosite1 Thrombin Inhibitor

Improved Inhibition of Protease-Activated Receptor 4 (PAR4) with Function-Blocking Antibodies Provides Equivalent Antithrombotic Activity in the Face of the Hyper-Reactive Thr120 PAR4 Variant

Phosphorylation of Y311 on Pkcδ Regulates Protease Activated Receptor 4-Mediated Signaling in Platelets

Expression of Functional Human Proteinase Activated Receptor (PAR)-1 on Mouse Platelets

Par-4 Overexpression Impedes Leukemogenesis in the Eµ-TCL1 Leukemia Model

PCTP (Phosphatidylcholine Transfer Protein) is Regulated By RUNX1 in Platelets/Megakaryocytes and is Associated with Adverse Cardiovascular Events

Platelet Membranes and Activation Pathway Determine Inhibitory Activity of Anti-Factor VIII C2 Domain Antibodies

Identification of Kinase-Dependent Signaling Pathways Regulated By Rap1b in Murine Platelets

Role of Prostate Apoptosis Response-4 Tumor Suppressor in the Survival and Growth of Chronic Lymphocytic Leukemia

Transcription Factor RUNX1 Regulates Pctp (Phosphatidylcholine Transfer Protein) in Platelets: A Potential Role in Regulating Platelet Function

Thrombin Induces Protease Activated Receptor (PAR)-3/-4 Interaction in Human Podocytes

Parstatin Mediates Platelet Activation That Is Unaffected By PAR Antagonism

Platelets and protease-activated receptor-4 contribute to acetaminophen-induced liver injury in mice

Distinct Genetic Loci Are Associated with Platelet Aggregation Responses to Collagen and Collagen Synthetic Related Peptide (SRP) in Mice

A Novel F2RL3 Variant Predicting a Tyr157Cys Substitution in Protease-Activated Receptor 4 Is Associated with Reduced Receptor Function in Platelets

Impaired Hemostasis Caused By Deficit of Tissue Factor-Triggered Blood Coagulation Leads to Alveolar Hemorrhages and Increased Mortality in Influenza A Infection

Thrombin Induces Apoptosis in Human and Rat Podocytes in a Protease Activated Receptor (PAR)-Dependent Manner

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American Society of Hematology

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American Society of Hematology

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