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Journal Articles

The Unfolded Protein Response Causes Prothrombotic Transformation of Pancreatic Cancer Linking Tumor Progression with Cancer-Associated Thrombosis

Oluwatoyosi Muse, PhD, Rushad Patell, MD, Christian Peters, PhD, Sol Schulman, MD PhD, Emale Darzi, MS, Calvin Schuster, BA, Ling Huang, PhD, Shibani Mukherjee, PhD, Senthil Muthuswamy, PhD, Jeffrey I. Zwicker, MD, Robert C. Flaumenhaft, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 632.
https://doi.org/10.1182/blood-2019-123544
Published: 2019
Journal Articles

Leukemia-Associated HSC Vascular Niche Is Negatively Regulated By PERK of Unfolded Protein Response (UPR)

Lan Zhou, MD, Cui Liu, MBBS, PhD, Stanley A Adoro, PhD BSc, MSc, Lechuang Chen, PhD, Diana Ramirez, PhD, Ge Jin, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2486.
https://doi.org/10.1182/blood-2019-127607
Published: 2019
Journal Articles

Dual Targeting of Cell-Cycle Checkpoint Kinase and Unfolded Protein Response As a Novel Therapeutic Approach for High-Risk Multiple Myeloma with TP53 Deletion or Mutations

Yuka Tanaka, MD, Takayuki Tabayashi, MD PhD, Yasuyuki Takahashi, MD PhD, Yuta Kimura, MD, Tatsuki Tomikawa, MD PhD, Junichi Watanabe, MD PhD, Tomoe Anan-Nemoto, MD PhD, Morihiko Sagawa, MD PhD, Reiko Watanabe, MD PhD, Michihide Tokuhira, Masahiro Kizaki, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5613.
https://doi.org/10.1182/blood-2018-99-116247
Published: 2018
Journal Articles

Characterization of a PERK Kinase Inhibitor with Anti-Myeloma Activity

Tina Bagratuni, Nefeli Mavrianou, Efstathios Kastritis, MD, Christine Liakos, Evangelos Terpos, MD, Meletios A. Dimopoulos
Journal: Blood
Blood (2015) 126 (23): 4188.
https://doi.org/10.1182/blood.V126.23.4188.4188
Published: 2015