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Peripheral B Cells from Patients with MGUS and Multiple Myeloma (MM) Can Be Stimulated by Paraprotein-Target Specific T-Helper Cells to Produce Paraprotein-Identical Monoclonal Antibodies: Rationale for PARs, a Novel Therapeutic Approach with Ultimate Specificity in MGUS/MM

Frank Neumann, PhD, Boris Kubuschok, MD, Klaus-Dieter Preuss, PhD, Claudia Schormann, Michael Pfreundschuh, MD
Journal: Blood
Blood (2015) 126 (23): 1817.
https://doi.org/10.1182/blood.V126.23.1817.1817
Published: 2015
Journal Articles

New Insights in the Pathogenesis of MGUS, Multiple Myeloma (MM) and Waldenström`s Macroglobulinemia (WM): Chronic Antigenic Stimulation by Autoantigenic Targets of Paraproteins Is Mediated by CD4 + t-Cells

Sandra Grass, MD, Klaus-Dieter Preuss, Aleksandra Wikowicz, Natalie Fadle, Evi Regitz, Gerhard Held, Leon Bernal-Mizrachi, MD, Sybille Raudies, Holger Thiele, Michael Pfreundschuh, MD, Frank Neumann
Journal: Blood
Blood (2011) 118 (21): 472.
https://doi.org/10.1182/blood.V118.21.472.472
Published: 2011
Journal Articles

Paraproteins of familial MGUS/multiple myeloma target family-typical antigens: hyperphosphorylation of autoantigens is a consistent finding in familial and sporadic MGUS/MM

Brief Report
Sandra Grass, Klaus-Dieter Preuss, Stephan Thome, Dennis D. Weisenburger, Vinetta Witt, Jane Lynch, Florian Zettl, Lorenz Trümper, Natalie Fadle, Evi Regitz, Henry Lynch, Michael Pfreundschuh
Journal: Blood
Blood (2011) 118 (3): 635–637.
https://doi.org/10.1182/blood-2011-01-331454
Published: 2011
Includes: Supplemental data
Journal Articles

Hyperphosphorylated paratarg-7: a new molecularly defined risk factor for monoclonal gammopathy of undetermined significance of the IgM type and Waldenström macroglobulinemia

Sandra Grass, Klaus-Dieter Preuss, Alexandra Wikowicz, Evangelos Terpos, Marita Ziepert, Diana Nikolaus, Yin Yang, Natalie Fadle, Evi Regitz, Meletios A. Dimopoulos, Steven P. Treon, Zachary R. Hunter, Michael Pfreundschuh
Journal: Blood
Blood (2011) 117 (10): 2918–2923.
https://doi.org/10.1182/blood-2010-09-306076
Published: 2011
Includes: Supplemental data
Journal Articles

Hyperphosphorylation of Antigenic Targets of Paraproteins In MGUS and Multiple Myeloma (MM) Is a Consistent Finding: Implications for the Pathogenesis of MGUS/MM

Sandra Grass, MD, Klaus-Dieter Preuss, Aleksandra Wikowicz, Natalie Fadle, Evi Regitz, Stephan D. Thome, MD, Henry T. Lynch, MD, Michael Pfreundschuh, MD
Journal: Blood
Blood (2010) 116 (21): 4085.
https://doi.org/10.1182/blood.V116.21.4085.4085
Published: 2010
Journal Articles

Expression of the leukemia oncogene Lmo2 is controlled by an array of tissue-specific elements dispersed over 100 kb and bound by Tal1/Lmo2, Ets, and Gata factors

Josette-Renée Landry, Nicolas Bonadies, Sarah Kinston, Kathy Knezevic, Nicola K. Wilson, S. Helen Oram, Mary Janes, Sandie Piltz, Michelle Hammett, Jacinta Carter, Tina Hamilton, Ian J. Donaldson, Georges Lacaud, Jonathan Frampton, George Follows, Valerie Kouskoff, Berthold Göttgens
Journal: Blood
Blood (2009) 113 (23): 5783–5792.
https://doi.org/10.1182/blood-2008-11-187757
Published: 2009
Includes: Supplemental data
Journal Articles

Cytokine Induced Changes in the Hematopoietic Stem Cell Trafficking Regulatory Peptidase CD26.

Kent W. Christopherson, PhD, Sherene E. Uralil, Shannon M. Kidd, Nehal K. Porecha, Ryan C. Zabriskie
Journal: Blood
Blood (2005) 106 (11): 5220.
https://doi.org/10.1182/blood.V106.11.5220.5220
Published: 2005