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Journal Articles

A Specific Mesenchymal Stem and Progenitor Cell (MSPC) Subpopulation with a Multi-Potent Gene Signature Is Transcriptionally Altered in the Setting of Myelodysplastic Syndrome (MDS) in Primary Human Bone Marrow Aspirates

Thomas J Fountaine, MD, Mark W LaMere, BA, Daniel K Byun, BS, Jason R Myers, MS, John M Ashton, PhD, Jane L. Liesveld, MD, Youmna Kfoury, PhD, David T. Scadden, MD, Michael W. Becker, MD, Laura M. Calvi, MD

Blood (2019) 134 (Supplement_1): 1708.

https://doi.org/10.1182/blood-2019-130227

Published: 2019

Journal Articles

Transcriptome Alterations of Isolated Primary Bone Marrow Endothelial Cells Provide Insigt to MGUS and Multiple Myeloma Pathobiology

Sandro Bräunig, MSc, Dimitra Zacharaki, PhD, Hongzhe Li, PhD, Hooi Ching Lim, PhD, Stefan Lang, PhD, Thoas Fioretos, MD PhD Prof., Stefan Scheding, MD

Blood (2019) 134 (Supplement_1): 4373.

https://doi.org/10.1182/blood-2019-128024

Published: 2019

Journal Articles

Towards a Standardization and Characterization of Clinical Grade Adipose-Derived Stromal Cells

Chiara Cugno, MD, Rita Calzone, Biologist, Giusy Gentilcore, PhD, Heba Sidahmed, Post Doctoral Fellow, Asma Al-Sulaiti, Research Specialist, Moza Al-Khulaifi, Rebecca Mathew, Harshitha Shobha Manjunath, Research Specialist, Sara Tomei, PhD, Ahmed Makki, MD, Jean-Charles Grivel, PhD

Blood (2019) 134 (Supplement_1): 5013.

https://doi.org/10.1182/blood-2019-130385

Published: 2019

Journal Articles

Polyunsaturated Fatty Acid (PUFA) Signaling Induces Ferroptosis-Mediated Cell-Death in Multiple Myeloma

Cristina Panaroni, PhD, Keertik Fulzele, PhD, Rosemary Soucy, Cherrie Huang, Kenta Mukaihara, MD PhD, Shrikanta Chattopadhyay, MBBS, Noopur S. Raje, MD

Blood (2019) 134 (Supplement_1): 3108.

https://doi.org/10.1182/blood-2019-131906

Published: 2019

Journal Articles

Acute Myeloid Leukemia Induced Remodelling of the Human Bone Marrow Niche Predicts Clinical Outcome

Yiyang Chen, Yasmin Zaun, MD, Lucas Arnold, Kerstin Weissenfels, Kurt Werner Schmid, Ludger Klein-Hitpass, PhD, Anthony Squire, Stefanie Bertram, MD, Ulrich Duehrsen, MD, Maher Hanoun, MD

Blood (2018) 132 (Supplement 1): 3851.

https://doi.org/10.1182/blood-2018-99-116317

Published: 2018

Journal Articles

Specific Bone Marrow Mesenchymal Subsets in Patients with Myelodysplastic Syndromes Harbor Molecular Perturbations That Alter the Dynamics of Competition between Pre-Leukemic Clones and Normal Cells

Youmna Kfoury, PhD, Esha Jain, Jason R Myers, MS, Fei Ji, David B Sykes, MD PhD, Francois Mercier, MD FRCPC, Ani Papazian, BS, Cam Le, Mark A Randolph, M.A.Sc., David P. Steensma, MD, Omar I Abdel-Wahab, MD, Laura M. Calvi, MD, Ruslan I Sadreyev, PhD, Michael W. Becker, MD, David T. Scadden, MD

Blood (2018) 132 (Supplement 1): 938.

https://doi.org/10.1182/blood-2018-99-115242

Published: 2018

Journal Articles

Transcriptome Alterations of Prospectively Isolated Bone Marrow Stromal Cells Provide Potential Cues to MGUS and Multiple Myeloma Pathobiology

Dimitra Zacharaki, Roshanak Ghazanfari, PhD, Hongzhe Li, PhD, Hooi Ching Lim, PhD, Sofia Von Palffy, Shamit Soneji, PhD, Thoas Fioretos, MD PhD, Stefan Scheding, MD

Blood (2017) 130 (Supplement 1): 4375.

https://doi.org/10.1182/blood.V130.Suppl_1.4375.4375

Published: 2017

Journal Articles

Impairment in the Mesenchymal Bone-Marrow Niche of Beta-Thalassemia Patients and Association with Prolonged Iron Exposure

Stefania Crippa, PhD, Valeria Rossella, Biologist, Laura Silvestri, PhD, Annamaria Aprile, PhD, Samantha Scaramuzza, Silvia Rivis, maria Antonietta Avanzini, Marco Zecca, MD, Sarah Marktel, MD, Fabio Ciceri, MD, Alessandro Aiuti, MD, Giuliana Ferrari, PhD, Maria Ester Bernardo, MD PhD

Blood (2017) 130 (Supplement 1): 948.

https://doi.org/10.1182/blood.V130.Suppl_1.948.948

Published: 2017

Journal Articles

High Molecular Weight Kininogen Alters the Tumor Microenvironment and Reduces Tumor Stem Cell Content

Meenal Shukla, James Hale, PhD, Justin Lathia, PhD, Keith McCrae, MD

Blood (2017) 130 (Supplement 1): 2340.

https://doi.org/10.1182/blood.V130.Suppl_1.2340.2340

Published: 2017

Journal Articles

Azacitidine Directly Acts on the Mesenchymal Stromal Cell Compartment in Myelodysplastic Syndromes to Alter Niche Function and Suppress Malignant Hematopoeitic Stem/Progenitor Cells

Catharina Wenk, MD, Anne-Kathrin Garz, MSc, Christina Huberle, MD, Sonja Grath, PhD, Denis Witham, Marie Weickert, Msc, Julia Niggemeyer, Msc, Judith Hecker, MD, Michele Kyncl, MSc, Catharina Müller-Thomas, MD, Christopher Mulholland, MSc, Robert A.J. Oostendorp, PhD, Klaus H. Metzeler, MD, Christian Peschel, MD, Katharina S Götze, MD

Blood (2017) 130 (Supplement 1): 1683.

https://doi.org/10.1182/blood.V130.Suppl_1.1683.1683

Published: 2017

Journal Articles

Early Growth Response (EGR)-1 Is a Key Regulator of Human Primary Bone Marrow Stroma Cells with a Dual Role in Proliferation and Hematopoietic Stroma Support Function

Hongzhe Li, PhD, Roshanak Ghazanfari, PhD, Hooi Ching Lim, PhD, Jenny Hansson, PhD, Dimitra Zacharaki, Stefan Scheding, MD

Blood (2017) 130 (Supplement 1): 3777.

https://doi.org/10.1182/blood.V130.Suppl_1.3777.3777

Published: 2017

Journal Articles

Genetically Engineered Regulatory T Cells for Treatment of Graft-Versus-Host-Disease

Eric Tu, PhD, Jennifer Fox, PhD, Christina Ly, BS, Christine Steinhart, PhD, Mike Laporte, MS, James Brennan, PhD, Cheryl Bolinger, PhD, Laurence J N Cooper, MDPhD, Hanspeter Waldner, PhD

Blood (2017) 130 (Supplement 1): 3176.

https://doi.org/10.1182/blood.V130.Suppl_1.3176.3176

Published: 2017

Journal Articles

Functional and Molecular Alterations of Bone Marrow Mesenchymal Stem and Progenitor Cells in Patients with Myelodysplastic Syndrome with Ring Sideroblast

Monika Dolinska, MSc, Pingnan Xiao, MD, Anne-Sofie Johansson, PhD, Lakshmi Sandhow, MSc, Makoto Kondo, PhD, Thibault Bouderlique, PhD, Johanna Ungerstedt, MD PhD, Eva Hellstrom-Lindberg, MD PhD, Hong Qian, PhD

Blood (2016) 128 (22): 1489.

https://doi.org/10.1182/blood.V128.22.1489.1489

Published: 2016

Journal Articles

Alteration of the Hematopoietic Components, Mesenchymal Stromal Cells and Vascular Elements in the Bone Marrow Niche in Myelodysplastic Syndrome: Refractory Cytopenia with Multilineage Dysplasia

Salar Abbas, M.Sc, Aparna Venkatraman, PhD, Sanjay Kumar, PhD, Archana Kini, M.Sc, Marie Therese Manipadam, MD, Vivi M Srivastava, MD, Eunice Sindhuvi, PhD, Vikram Mathews, MD DM, Biju George, MD DM, Alok Srivastava

Blood (2016) 128 (22): 5516.

https://doi.org/10.1182/blood.V128.22.5516.5516

Published: 2016

Journal Articles

Allogeneic Genetically Modified T Cells (HSV-TK) As Adjunctive Treatment in Haploidentical Hematopoietic Stem-Cell Transplantation (haplo-HSCT) of Adult Patients with High-Risk Hematological Malignancies: A Pair-Matched Analysis from the Acute Leukemia Working Party of EBMT

Mohamad Mohty, MD PhD, Myriam Labopin, MD, Andrea Velardi, MD, Maria Teresa van Lint, MD, Donald Bunjes, Benedetto Bruno, MD PhD, Stella Santarone, MD, Johanna Tischer, Yener Koc, MD, Depei Wu, MDPhD, Zafer Gulbas, MD, Annalisa Ruggeri, MD, Florent Malard, MD PhD, Simona Piemontese, MD, Maria Teresa Lupo Stanghellini, MD, Chiara Bonini, MD, Claudio Bordignon, MD, Fabio Ciceri, MD, Arnon Nagler

Blood (2016) 128 (22): 672.

https://doi.org/10.1182/blood.V128.22.672.672

Published: 2016

Journal Articles

Early Growth Response (EGR)-1 Expression Regulates Colony Forming Capacity and Hematopoietic Support Function in Human Primary Bone Marrow Stromal Stem Cells

Hongzhe Li, PhD, Roshanak Ghazanfari, Dimitra Zacharaki, Hooi Ching Lim, PhD, Stefan Scheding, MD

Blood (2016) 128 (22): 3886.

https://doi.org/10.1182/blood.V128.22.3886.3886

Published: 2016

Journal Articles

Following Autologous Stem Cell Transplantation (1 Yr) Mesenchymal Stem Cells Are Functionally Impaired with Reduced Hematopoietic Support

Catharina Hazenberg, MD, Fiona A.J. van den Heuvel, Edo Vellenga, MD PhD, Annet Z. Brouwers-Vos, Gerbrig Berger, BSc, Jan Jacob Schuringa, PhD

Blood (2016) 128 (22): 3888.

https://doi.org/10.1182/blood.V128.22.3888.3888

Published: 2016

Journal Articles

Inflammatory Niche Signalling Drives Genotoxic Stress in Hematopoietic Stem Cells and Predicts Leukemic Evolution in Human Leukemia Predisposition Syndromes

Blood (2016) 128 (22): 428.

https://doi.org/10.1182/blood.V128.22.428.428

Published: 2016

Journal Articles

Mechanisms of Suppressive Effects of MYD88 Inhibitors on the Growth of Lymphoma and Leukemia Cells

Erika Shiratori, Mai Itoh, PhD, Mika Ohtaka, Shohei Nogami, Shuji Tohda, MD PhD

Blood (2016) 128 (22): 2773.

https://doi.org/10.1182/blood.V128.22.2773.2773

Published: 2016

Journal Articles

Distinct Stress Responses of Bone Marrow Stromal Cell Subgroups Defined by Unbiased Single-Cell Mass-Cytometry Analysis

Nicolas Severe, PhD, Murat Karabacak, PhD, Ninib Baryawno, PhD, Karin Gustafsson, PhD, Youmna Sami Kfoury, PhD, Mehmet Toner, PhD, David T. Scadden, MD

Blood (2016) 128 (22): 430.

https://doi.org/10.1182/blood.V128.22.430.430

Published: 2016

NARROW

A Specific Mesenchymal Stem and Progenitor Cell (MSPC) Subpopulation with a Multi-Potent Gene Signature Is Transcriptionally Altered in the Setting of Myelodysplastic Syndrome (MDS) in Primary Human Bone Marrow Aspirates

Transcriptome Alterations of Isolated Primary Bone Marrow Endothelial Cells Provide Insigt to MGUS and Multiple Myeloma Pathobiology

Towards a Standardization and Characterization of Clinical Grade Adipose-Derived Stromal Cells

Polyunsaturated Fatty Acid (PUFA) Signaling Induces Ferroptosis-Mediated Cell-Death in Multiple Myeloma

Acute Myeloid Leukemia Induced Remodelling of the Human Bone Marrow Niche Predicts Clinical Outcome

Specific Bone Marrow Mesenchymal Subsets in Patients with Myelodysplastic Syndromes Harbor Molecular Perturbations That Alter the Dynamics of Competition between Pre-Leukemic Clones and Normal Cells

Transcriptome Alterations of Prospectively Isolated Bone Marrow Stromal Cells Provide Potential Cues to MGUS and Multiple Myeloma Pathobiology

Impairment in the Mesenchymal Bone-Marrow Niche of Beta-Thalassemia Patients and Association with Prolonged Iron Exposure

High Molecular Weight Kininogen Alters the Tumor Microenvironment and Reduces Tumor Stem Cell Content

Azacitidine Directly Acts on the Mesenchymal Stromal Cell Compartment in Myelodysplastic Syndromes to Alter Niche Function and Suppress Malignant Hematopoeitic Stem/Progenitor Cells

Early Growth Response (EGR)-1 Is a Key Regulator of Human Primary Bone Marrow Stroma Cells with a Dual Role in Proliferation and Hematopoietic Stroma Support Function

Genetically Engineered Regulatory T Cells for Treatment of Graft-Versus-Host-Disease

Functional and Molecular Alterations of Bone Marrow Mesenchymal Stem and Progenitor Cells in Patients with Myelodysplastic Syndrome with Ring Sideroblast

Alteration of the Hematopoietic Components, Mesenchymal Stromal Cells and Vascular Elements in the Bone Marrow Niche in Myelodysplastic Syndrome: Refractory Cytopenia with Multilineage Dysplasia

Allogeneic Genetically Modified T Cells (HSV-TK) As Adjunctive Treatment in Haploidentical Hematopoietic Stem-Cell Transplantation (haplo-HSCT) of Adult Patients with High-Risk Hematological Malignancies: A Pair-Matched Analysis from the Acute Leukemia Working Party of EBMT

Early Growth Response (EGR)-1 Expression Regulates Colony Forming Capacity and Hematopoietic Support Function in Human Primary Bone Marrow Stromal Stem Cells

Following Autologous Stem Cell Transplantation (1 Yr) Mesenchymal Stem Cells Are Functionally Impaired with Reduced Hematopoietic Support

Inflammatory Niche Signalling Drives Genotoxic Stress in Hematopoietic Stem Cells and Predicts Leukemic Evolution in Human Leukemia Predisposition Syndromes

Mechanisms of Suppressive Effects of MYD88 Inhibitors on the Growth of Lymphoma and Leukemia Cells

Distinct Stress Responses of Bone Marrow Stromal Cell Subgroups Defined by Unbiased Single-Cell Mass-Cytometry Analysis

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American Society of Hematology

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American Society of Hematology

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