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Journal Articles

The Paracaspase MALT1 Acts Independently of Pre-B-Cell Receptor Signaling As a Key Factor in Leukemic Cell Survival in Precursor B-Cell Acute Lymphoblastic Leukemia

Nakhle S. Saba, MD, Jade Meyers, Lorena Fontan, PhD, Ari Melnick, MD, Adrian Wiestner, MD PhD, Patricia Lobelle-Rich, Ekaterina Kim, MS, Jan A. Burger, MD PhD, Yara Mouawad, MD, Prescott L. Deininger, PhD, Francisco Socola, MD, Hana Safah, MD, Erik K Flemington, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1288.
https://doi.org/10.1182/blood-2019-131376
Published: 2019
Journal Articles

Targeting the Paracaspase MALT1: A Potential Therapy to Overcome Ibrutinib Resistance in Relapsed/Refractory Mantle Cell Lymphoma Patients

Changying Jiang, PhD, Shengjian Huang, PhD, Yang Liu, MD, Carrie Li, Hui Guo, MD PhD, Jeffrey Wang, Elyse Lopez, Hui Zhang, Elizabeth A Lorence, MPH, Maria Merolle, Swathi Balaji, Makhdum Ahmed, MD MPH, PhD, Krystle Nomie, PhD, Xin Lin, PhD, Liang Zhang, MD PhD, Michael Wang, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 574.
https://doi.org/10.1182/blood.V130.Suppl_1.574.574
Published: 2017
Journal Articles

Targeting MALT1 with the Small Molecule Inhibitor MI2 Induces a Caspase-Dependent Apoptosis and Inhibits the NF-κb Pathway in Chronic Lymphocytic Leukemia Primary Cells

Georges Tanios, MD, Patricia Lobelle-Rich, Ashwin Vasudevamurthy, MD, Thomas S. Atkinson, MD, Ali Baghian, MD, Delong Liu, PhD, Hana Safah, MD, Erik K. Flemington, PhD, Nakhle S. Saba, MD
Journal: Blood
Blood (2016) 128 (22): 1597.
https://doi.org/10.1182/blood.V128.22.1597.1597
Published: 2016
Journal Articles

RNA Interference Screen Implicates TNFAIP3 and FOXO1 in MALT1 Inhibition Resistance

Lorena Fontan, PhD, Rebecca Goldstein, PhD, Gabriella Casalena, PhD, Himaly Shinglot, MS, Ilkay Us, MS, Haiying Ju, MS, Yanwen Jiang, PhD, Natalia Bilchuk, MS, Ari Melnick, MD
Journal: Blood
Blood (2016) 128 (22): 837.
https://doi.org/10.1182/blood.V128.22.837.837
Published: 2016
Journal Articles

Inhibition of MALT1 Protease Activity Is Selectively Toxic for Activated B CellÃ,–Like Diffuse Large B Cell Lymphoma Cells.

Uta Ferch, Bernhard Kloo, Andreas Gewies, Vera Pfaender, Michael Düwel, Christian Peschel, MD, Daniel Krappmann, Jürgen Ruland
Journal: Blood
Blood (2009) 114 (22): 1271.
https://doi.org/10.1182/blood.V114.22.1271.1271
Published: 2009
Journal Articles

Novel Fusion of the MALT1/MLT and MAP4 Genes Detected in a Diffuse Large B-Cell Lymphoma.

Eva M. Murga Penas, PhD, Kristina Hinz, Petra Behrmann, Martin L. Hansmann, MD, Claudia Becher, Reiner Siebert, MD, Judith Dierlamm, MD, on Behalf of the Network Project “Molecular Mechanisms of Malignant Lymphomas”
Journal: Blood
Blood (2005) 106 (11): 2838.
https://doi.org/10.1182/blood.V106.11.2838.2838
Published: 2005
Journal Articles

MALT1 Is an Essential Regulator of Antigen Receptor Mediated NF-kappaB Activation.

Jürgen Ruland, MD, Tak Mak, PhD
Journal: Blood
Blood (2004) 104 (11): 347.
https://doi.org/10.1182/blood.V104.11.347.347
Published: 2004
Journal Articles

Quantitative Proteomic Profiling of Primary Cutaneous CD30+ T-Cell Lymphoma Progression.

Kalpana S. Reddy, MD, David K. Crockett, Marshall E. Kadin, MD, Kojo S.J. Elenitoba-Johnson, MD, Megan S. Lim, MD, PhD
Journal: Blood
Blood (2004) 104 (11): 2270.
https://doi.org/10.1182/blood.V104.11.2270.2270
Published: 2004