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Journal Articles

Targeting Nucleolin for Reversal of Chemotherapy Resistance in Acute Lymphoblastic Leukemia

Jianda Hu, PhD, Yanxin Chen, MD PhD, Zhengjun Wu, Lingyan Wang, PhDMD, Jingjing Wen, Peifang Jiang, Yun Zhang, Minhui Lin, MD PhD

Blood (2019) 134 (Supplement_1): 5058.

https://doi.org/10.1182/blood-2019-127073

Published: 2019

Journal Articles

Targeting AML: The Development of Two Functionally and Mechanistically Distinct Classes of Cereblon-Mediated Protein Homeostatic Modulators

Aparajita Hoskote Chourasia, PhD, Leah Fung, PhD, Brooke McElwee, BSc, Normand Richard, MSc, Imelda Lam, BSc, Eduardo Torres, MSc, Paul Erdman, MSc, Robert Sullivan, PhD, David Hecht, PhD, Kyle WH Chan, PhD, Frank Mercurio, PhD, David I Stirling, PhD

Blood (2019) 134 (Supplement_1): 3361.

https://doi.org/10.1182/blood-2019-131872

Published: 2019

Journal Articles

A Novel Class of Bifunctional Immunotherapeutic That Exploits a Universal Antibody Binding Terminus (uABT) to Recruit Endogenous Antibodies to Cell Expressing CD38 Demonstrate In Vivo efficacy in Three Distinct Animal Models

Anna Bunin, PhD, Katy McGrath, BS, Ann Marie Rossi, MS, Matthew Welsch, PhD, Christian Vidal, PhD, David Trinh, BA, David Spiegel, MD, PhD, Luca Rastelli, PhD, Enrique Alvarez, DVM

Blood (2019) 134 (Supplement_1): 1820.

https://doi.org/10.1182/blood-2019-130838

Published: 2019

Journal Articles

Hexabody-CD38, a Novel CD38 Antibody with a Hexamerization Enhancing Mutation, Demonstrates Enhanced Complement-Dependent Cytotoxicity and Shows Potent Anti-Tumor Activity in Preclinical Models of Hematological Malignancies

Bart ECG De Goeij, PhD, Maarten L Janmaat, PhD, Grietje Andringa, Laurens Kil, Berris Van Kessel, Kristine A. Frerichs, MD, Andreas Lingnau, Andreas Freidig, Tuna Mutis, MD PhD, A. Kate Sasser, Esther C. W. Breij, Niels W. C. J. Van De Donk, MD PhD, Tahamtan Ahmadi, David Satijn

Blood (2019) 134 (Supplement_1): 3106.

https://doi.org/10.1182/blood-2019-125788

Published: 2019

Journal Articles

SHP-1 As a Negative Regulator of FLT3 Associated Aberrant Signaling and a New Potential Target to FLT3-ITD Mutation

Tongjuan Li, MD PhD, Dan Li, Lei Zhao, MD, Jue Wang, MD PhD, Zhen Shang, MD PhD, Yicheng Zhang, MD PhD, Liang Huang, MD PhD, Jianfeng Zhou, PhD

Blood (2018) 132 (Supplement 1): 4051.

https://doi.org/10.1182/blood-2018-99-115793

Published: 2018

Journal Articles

Role of AML1-ETO Related Fusion Circular RNA in the Growth of Leukemia Cells

Ying Wang, MD, Yingxi Xu, PhD, Qian Liu, Haiyan Xing, MS, Zheng Tian, BS, Kejing Tang, BS, Qing Rao, MS, Min Wang, MD, Jianxiang Wang, MD

Blood (2018) 132 (Supplement 1): 5130.

https://doi.org/10.1182/blood-2018-99-112728

Published: 2018

Journal Articles

Establishment of Human Acute Monocyte Leukemia Model with Systemic Leukemia in Npg Mice

Jing Xu, Zhenjiang Li, Qiong Wu, Wenfeng He, Jifu Zheng, Qingming Wang, Aiping Tang, Wanlei Sun, Yanfei Rao

Blood (2018) 132 (Supplement 1): 4041.

https://doi.org/10.1182/blood-2018-99-112395

Published: 2018

Journal Articles

Ubiquitin-Activating Enzyme E1 Inhibition Caused Acute Leukemia Cell Apoptosis By Affecting CHOP Pathway

Ju Bai, PhD, Aili He, MD, Jianli Wang, MD, Yun Yang, MD, Ying Shen, MD, Yuandong Feng, MD, Yan Xu

Blood (2018) 132 (Supplement 1): 2784.

https://doi.org/10.1182/blood-2018-99-118162

Published: 2018

Journal Articles

Cy7-Tocilizumab/Fab(Tocilizumab): Near Infrared Fluorescence In Vivo Imaging of Multiple Myeloma

Ximena Camacho, MSc, Carolina Perroni, Lic, Mara de Souza Junqueira, Marcelo Fernandez, Roger Chammas, Carlos Buchpiguel, Juan Pablo Gambini, Pablo Cabral, Eloisa Riva, MD

Blood (2018) 132 (Supplement 1): 5621.

https://doi.org/10.1182/blood-2018-99-114186

Published: 2018

Journal Articles

The Novel HDAC Inhibitor Chidamide Synergizes with Rituximab to Inhibit DLBCL Tumor Growth in Vitro and In Vivo By up-Regulating CD20 Expression

Xu-Wen Guan, MD, Wang Hua-Qing, MD PhD, Li Jia, MD PhD, Feng-Ting Liu, MB, PhD

Blood (2018) 132 (Supplement 1): 2947.

https://doi.org/10.1182/blood-2018-99-114598

Published: 2018

Journal Articles

Pyrvinium Pamoate Overcomes Cabozantinib-Resistance of FLT3 -ITD AML Cells through Modulating the Mitochondria Functions and Signaling Pathways

Yu-Hsuan Fu, BS, Wen-Hui Lu, MS, Pei-Qi Lan, MS, Chung-Yi Hu, PhD, Chien-Yuan Chen, MD, PhD, Da-Liang Ou, PhD, Hwei-Fang Tien, MD, PhD, Liang-In Lin, PhD

Blood (2018) 132 (Supplement 1): 4683.

https://doi.org/10.1182/blood-2018-99-118476

Published: 2018

Journal Articles

Targeting T-Cell Receptor Signaling Pathway in Angioimmunoblastic T-Cell Lymphoma

Tran B. Nguyen, Mamiko Sakata-Yanagimoto, MD PhD, Manabu Fujisawa, MD, Shigeru Chiba, MD PhD

Blood (2017) 130 (Supplement 1): 572.

https://doi.org/10.1182/blood.V130.Suppl_1.572.572

Published: 2017

Journal Articles

Therapeutic Efficacy of Mcl-1 Antagonism in Large Granular Lymphocyte Leukemia

Francis R LeBlanc, PhD, Jun Yang, MD, John H Heller, B.S., Shubha Dighe, M.S., Alejandro A. Gru, MD, Marya Dunlap-Brown, M.S., Hong-Gang Wang, PhD, David J Feith, PhD, Thomas P Loughran, Jr., MD

Blood (2017) 130 (Supplement 1): 1217.

https://doi.org/10.1182/blood.V130.Suppl_1.1217.1217

Published: 2017

Journal Articles

Novel Bispecific Antibody Targeting CD45 and 90 Y-DOTA Is Effective Therapy for Acute Myeloid Leukemia in Preclinical Murine Models

Johnnie J. Orozco, MD PhD, Aimee Kenoyer, BS, Yukang Lin, PhD, Darrell R. Fisher, PhD, Donald K. Hamlin, BS, D. Scott Wilbur, PhD, Alexandra Hernandez, BS, Rosario Guel, Margaret E. Nartea, Shyril O'Steen, PhD, Mark D Hylarides, PhD, Brian G Till, MD, Damian J. Green, MD, Ajay K. Gopal, MD, Kelly D Orcutt, PhD, Karl Dane Wittrup, PhD, Brenda M. Sandmaier, MD, John M. Pagel, MD PhD, Oliver W. Press, MD PhD

Blood (2017) 130 (Supplement 1): 1355.

https://doi.org/10.1182/blood.V130.Suppl_1.1355.1355

Published: 2017

Journal Articles

Small Interfering RNA-Mediated Knockdown of SATB1 Increases Cell Proliferation through NF-κb Activation in Acute Myeloid Leukemia

Xiaodan Luo, Xiaohong Wu, Lihua Xu, Huo Tan

Blood (2017) 130 (Supplement 1): 1238.

https://doi.org/10.1182/blood.V130.Suppl_1.1238.1238

Published: 2017

Journal Articles

Aurora A Kinase As a Promising Therapeutic Target in Philadelphia Chromosome Positive Leukemia Cells

Seiichi Okabe, MD PhD, Tetsuzo Tauchi, MD, Yuko Tanaka, MD PhD, Kazuma Ohyashiki, MD PhD

Blood (2017) 130 (Supplement 1): 3828.

https://doi.org/10.1182/blood.V130.Suppl_1.3828.3828

Published: 2017

Journal Articles

CTLA4-FasL, the Hexameric Targeted FasL Fusion Protein, As Potential Novel Treatment for DLBCL

Alexandra Aronin, PhD, Liat Ben Gigi-Tamir, PhD, Efi Makdasi, PhD, Shira Amsili, PhD, Shlomi Ben David, Ortal Avraham, Yehudith Jitka Sagiv, Yosi Meir Gozlan, PhD, Noam Shani, PhD, Michal Dranitzki Elhalel, MD MSc

Blood (2017) 130 (Supplement 1): 4107.

https://doi.org/10.1182/blood.V130.Suppl_1.4107.4107

Published: 2017

Journal Articles

Dual Inhibition of Aurora Kinase and BRD4 Leads to Improved Anti-Tumor Activity in Myc-Overexpressing Lymphoma Cells

Steven I Park, MD, Carolina Lin, Lawrence J Druhan, PhD, Michael B Foote, Trevor Parton, Natalie Ren, Steven P Angus, Aadra P Bhatt, Scott C Jaros, Nilanjan Ghosh, MD PhD, Ryan Jacobs, MD, Belinda Rene Avalos, MD, Dirk P Dittmer, PhD, Norman E. Sharpless, MD, Blossom A Damania

Blood (2017) 130 (Supplement 1): 4109.

https://doi.org/10.1182/blood.V130.Suppl_1.4109.4109

Published: 2017

Journal Articles

PCT3, a Combination of Active Steroidal Saponins from the Paris Forrestii (Takht.) H. Li, Displays Potent Activity Against Acute Myeloid Leukemia By Suppressing the PBX1/RNF6/AKT/mTOR Signaling Pathway

Qin Lu, MD, Yunjing Zheng, MD, Yuehu Wang, PhD, Jian Pan, PhD, Xinliang Mao, MD PhD, Shaoyan Hu, MD PhD

Blood (2017) 130 (Supplement 1): 2533.

https://doi.org/10.1182/blood.V130.Suppl_1.2533.2533

Published: 2017

Journal Articles

Xpo-1 Inhibition Synergizes with BCR Inhibition, Blocks Tumor Growth and Tumor-Associated Macrophages Infiltration and Prolongs Survival in a Bioluminescent Animal Model of Primary Central Nervous System Lymphoma

Marta Crespo, PhD, Júlia Carabia, MSc, Isabel Jiménez, MSc, Sabela Bobillo, MD, Pau Abrisqueta, MD PhD, Carles Palacio, MD, Juan C Nieto, PhD, Joan Boix, BSc, Cecilia Carpio, MD, Josep Castellvi, Joan Seoane, Francesc Bosch

Blood (2017) 130 (Supplement 1): 2808.

https://doi.org/10.1182/blood.V130.Suppl_1.2808.2808

Published: 2017

NARROW

Targeting Nucleolin for Reversal of Chemotherapy Resistance in Acute Lymphoblastic Leukemia

Targeting AML: The Development of Two Functionally and Mechanistically Distinct Classes of Cereblon-Mediated Protein Homeostatic Modulators

A Novel Class of Bifunctional Immunotherapeutic That Exploits a Universal Antibody Binding Terminus (uABT) to Recruit Endogenous Antibodies to Cell Expressing CD38 Demonstrate In Vivo efficacy in Three Distinct Animal Models

Hexabody-CD38, a Novel CD38 Antibody with a Hexamerization Enhancing Mutation, Demonstrates Enhanced Complement-Dependent Cytotoxicity and Shows Potent Anti-Tumor Activity in Preclinical Models of Hematological Malignancies

SHP-1 As a Negative Regulator of FLT3 Associated Aberrant Signaling and a New Potential Target to FLT3-ITD Mutation

Role of AML1-ETO Related Fusion Circular RNA in the Growth of Leukemia Cells

Establishment of Human Acute Monocyte Leukemia Model with Systemic Leukemia in Npg Mice

Ubiquitin-Activating Enzyme E1 Inhibition Caused Acute Leukemia Cell Apoptosis By Affecting CHOP Pathway

Cy7-Tocilizumab/Fab(Tocilizumab): Near Infrared Fluorescence In Vivo Imaging of Multiple Myeloma

The Novel HDAC Inhibitor Chidamide Synergizes with Rituximab to Inhibit DLBCL Tumor Growth in Vitro and In Vivo By up-Regulating CD20 Expression

Pyrvinium Pamoate Overcomes Cabozantinib-Resistance of FLT3 -ITD AML Cells through Modulating the Mitochondria Functions and Signaling Pathways

Targeting T-Cell Receptor Signaling Pathway in Angioimmunoblastic T-Cell Lymphoma

Therapeutic Efficacy of Mcl-1 Antagonism in Large Granular Lymphocyte Leukemia

Novel Bispecific Antibody Targeting CD45 and 90 Y-DOTA Is Effective Therapy for Acute Myeloid Leukemia in Preclinical Murine Models

Small Interfering RNA-Mediated Knockdown of SATB1 Increases Cell Proliferation through NF-κb Activation in Acute Myeloid Leukemia

Aurora A Kinase As a Promising Therapeutic Target in Philadelphia Chromosome Positive Leukemia Cells

CTLA4-FasL, the Hexameric Targeted FasL Fusion Protein, As Potential Novel Treatment for DLBCL

Dual Inhibition of Aurora Kinase and BRD4 Leads to Improved Anti-Tumor Activity in Myc-Overexpressing Lymphoma Cells

PCT3, a Combination of Active Steroidal Saponins from the Paris Forrestii (Takht.) H. Li, Displays Potent Activity Against Acute Myeloid Leukemia By Suppressing the PBX1/RNF6/AKT/mTOR Signaling Pathway

Xpo-1 Inhibition Synergizes with BCR Inhibition, Blocks Tumor Growth and Tumor-Associated Macrophages Infiltration and Prolongs Survival in a Bioluminescent Animal Model of Primary Central Nervous System Lymphoma

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ASH Publications

American Society of Hematology

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ASH Publications

American Society of Hematology

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