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    Journal Articles

    IDH1 Mutant AML Is Susceptible to Targeting De Novo Lipid Synthesis Independent of 2-Hydroxyglutarate and Has a Distinct Metabolic Profile from IDH2 Mutant AML

    Daniel Thomas, MD PhD, Yusuke Nakauchi, MD PhD, Manhong Wu, PhD, Ming Zheng, PhD, Subarna Sinha, PhD, David Dill, PhD, Gary Peltz, MD PhD, Ravindra Majeti, MD PhD
    Journal: Blood
    Blood (2018) 132 (Supplement 1): 440.
    https://doi.org/10.1182/blood-2018-99-115040
    Published: 2018
    Journal Articles

    Isocitrate Dehydrogenase 1 Mutant Cancers Are Metabolically Vulnerable to Inhibition of Acetyl CoA Carboxylase Via a 2-Hydroxyglutarate Independent Mechanism

    Daniel Thomas, MD PhD, Subarna Sinha, PhD, Steven M. Chan, MD PhD, Manhong Wu, Damoun Torabi, Gary Peltz, MD PhD, Yang Gao, David L Dill, PhD, Ravi Majeti, MD PhD
    Journal: Blood
    Blood (2016) 128 (22): 1054.
    https://doi.org/10.1182/blood.V128.22.1054.1054
    Published: 2016

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