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Journal Articles

Inhibition of BMP-Smad Pathway Reduces Leukemic Stemness in Pediatric AML

Xin Long, PhD, Chris Man, PhD, Padmini Narayanan, PhD, Elizabeth Seashore, MD, Michele Redell, MD PhD

Blood (2019) 134 (Supplement_1): 3731.

https://doi.org/10.1182/blood-2019-129074

Published: 2019

Journal Articles

Preliminary Lasso Regression Analysis Identifies DNA-Damage Gene Expression Signature Predictive of Clinical Outcomes in Patients Using Gemtuzumab Ozogamicin

Mohammed Gbadamosi, BS, Abdelrahman H. Elsayed, MSc, Rhonda E. Ries, MA, Soheil Meshinchi, MD PhD, Jatinder K Lamba, M.Sc., PhD

Blood (2019) 134 (Supplement_1): 1401.

https://doi.org/10.1182/blood-2019-131210

Published: 2019

Journal Articles

Bone Marrow Mesenchymal Stromal Cells and Inflammation Contribute to ETV6-RUNX1 + Preleukemic Cells Persistence and DNA Damaging

Linda Beneforti, Erica Dander, PhD, Silvia Bresolin, PhD, Clara Bueno, Geertruy te Kronnie, Anthony Ford, Pablo Menendez, Giovanna D'Amico, BSc, PhD MSc, Andrea Biondi, Chiara Palmi, Giovanni Cazzaniga, PhD

Blood (2018) 132 (Supplement 1): 3918.

https://doi.org/10.1182/blood-2018-99-114791

Published: 2018

Journal Articles

Dual Targeting of Cell-Cycle Checkpoint Kinase and Unfolded Protein Response As a Novel Therapeutic Approach for High-Risk Multiple Myeloma with TP53 Deletion or Mutations

Yuka Tanaka, MD, Takayuki Tabayashi, MD PhD, Yasuyuki Takahashi, MD PhD, Yuta Kimura, MD, Tatsuki Tomikawa, MD PhD, Junichi Watanabe, MD PhD, Tomoe Anan-Nemoto, MD PhD, Morihiko Sagawa, MD PhD, Reiko Watanabe, MD PhD, Michihide Tokuhira, Masahiro Kizaki, MD PhD

Blood (2018) 132 (Supplement 1): 5613.

https://doi.org/10.1182/blood-2018-99-116247

Published: 2018

Journal Articles

Upregulation of Alternatively Glycosylated Smoothened (SMO) Is Involved in Doxorubicin (DXR) Resistance in Diffuse Large B-Cell Lymphoma

Nitin Agarwal, PhD, Kranthi Kunkalla, MS, Sandra Sanchez, MD, Amineh Vaghefi, MD, Darius Juskevicius, PhD, Alexandar Tzankov, Ramiro E Verdun, PhD, Ralf Landgraf, PhD, Francisco Vega, MD PhD

Blood (2017) 130 (Supplement 1): 3839.

https://doi.org/10.1182/blood.V130.Suppl_1.3839.3839

Published: 2017

Journal Articles

The Bone Marrow Environment Promotes Resistance to Mitoxantrone and Etoposide By Distinct Mechanisms in Pediatric AML

Xin Long, PhD, Michele S. Redell, MD PhD

Blood (2016) 128 (22): 3943.

https://doi.org/10.1182/blood.V128.22.3943.3943

Published: 2016

Journal Articles

Inhibition of WEE1 Induces Cell Death of Both Bortezomib- and Lenalidomide-Resistant Multiple Myeloma Cells: A Novel Therapeutic Approach Targeting Cell-Cycle Checkpoint Kinase

Takayuki Tabayashi, MD PhD, Yuka Tanaka, MD, Yasuyuki Takahashi, MD, Yuta Kimura, MD, Tatsuki Tomikawa, MD, Morihiko Sagawa, MD PhD, Tomoe Anan-Nemoto, MDPhD, Reiko Watanabe, MD PhD, Michihide Tokuhira, MD PhD, Masahiro Kizaki, MD PhD

Blood (2016) 128 (22): 3256.

https://doi.org/10.1182/blood.V128.22.3256.3256

Published: 2016

Journal Articles

The Role of UBR5 Mutations in the Pathogenesis of Mantle CELL Lymphoma

Olga Kutovaya, PhD, Stacy Hung, PhD, Hughes Christopher, PhD, Randy D Gascoyne, MD, Morin Gregg, PhD, Christian Steidl

Blood (2016) 128 (22): 4124.

https://doi.org/10.1182/blood.V128.22.4124.4124

Published: 2016

Journal Articles

Age-Related Changes in the Interaction of Acute Myeloid Leukemia with the Bone Marrow Microenvironment Correlate with Response to Treatment and Survival: A Role for L-Selectin

Joe C Huang, MD, Yifan Lu, B.S., Julia Sidorova, PhD, Sylvia Chien, Vivian Oehler, MD, Kenneth J Kopecky, PhD, Pamela S. Becker, MD PhD

Blood (2016) 128 (22): 5063.

https://doi.org/10.1182/blood.V128.22.5063.5063

Published: 2016

Journal Articles

The mTOR Inhibitor Everolimus Overcomes CXCR4-Mediated Resistance to HDAC Inhibitor Panobinostat through Inhibition of p21 and Mitosis Regulators, Sensitizing MM Cells to DNA-Damaged Induced Apoptosis

Katia Beider, PhD, Valeria Voevoda, Hanna Bitner, Evgenia Rosenberg, Hila Magen, MD, Olga Ostrovsky, PhD, Merav Leiba, MD, Noya Shilo, MD, Avichai Shimoni, MD, Michael Milyavsky, PhD, Amnon Peled, PhD, Arnon Nagler

Blood (2016) 128 (22): 891.

https://doi.org/10.1182/blood.V128.22.891.891

Published: 2016

Journal Articles

Molecular Mechanism and Optimal Treatment Strategy in Acute Myeloid Leukemia with Resistance to Drugs and Radiation By NVP-LED225

Fanyi Meng, Xiaodong Li, Bingjie Ding, Kaikai Huang, Qiuhua Zhu, Fang Chen, Yufeng Zhu

Blood (2015) 126 (23): 3691.

https://doi.org/10.1182/blood.V126.23.3691.3691

Published: 2015

Journal Articles

ANKHD1 Is Essential for Repair of DNA Double-Strand Breaks in Multiple Myeloma

Anamika Dhyani, PhD, Patricia Favaro, PhD, Sara T. Olalla Saad, MD, PhD

Blood (2015) 126 (23): 1762.

https://doi.org/10.1182/blood.V126.23.1762.1762

Published: 2015

Journal Articles

Premature Senescence in Hematopoietic Stem and Progenitor Cells in Ribosomopathy-Associated Bone Marrow Failure Syndromes

Hengjun Chao, MD, Johnson M. Liu, MD

Blood (2015) 126 (23): 298.

https://doi.org/10.1182/blood.V126.23.298.298

Published: 2015

Journal Articles

A Novel Alkylating Agent Melphalan Flufenamide Ethyl Ester Induces an Irreversible DNA Damage in Multiple Myeloma Cells

Arghya Ray, PhD, Durgadevi Ravillah, PhD, Deepika Sharma Das, PhD, Yan Song, PhD, Eva Nordström, Jakob Lindberg, Paul G. Richardson, Dharminder Chauhan, PhD, Kenneth C. Anderson, MD

Blood (2014) 124 (21): 2086.

https://doi.org/10.1182/blood.V124.21.2086.2086

Published: 2014

Journal Articles

Activation Induced Cytidine Deaminase-Associated DNA Repair Pathways Influence Germinal Center B Cell Lymphomagenesis

Xiwen Gu, Ph.D., Carmen J. Booth, D.V.M., Ph.D., Zongzhi Liu, Ph.D., Matthew P. Strout, M.D., Ph.D.

Blood (2013) 122 (21): 1247.

https://doi.org/10.1182/blood.V122.21.1247.1247

Published: 2013

Journal Articles

The Splicing Factor Heterogeneous Nuclear Ribonucleoprotein L (hnRNPL) Restricts p53 Dependent and p53 Independent Cell Death Pathways In Hematopoietic Stem Cells

Marie-Claude Gaudreau, MSc, PhD, Damien Grapton, MSc, Florian Heyd, PhD, Charles Vadnais, Ph.D., Brian T Wilhelm, Ph.D., Tarik Moroy, PhD

Blood (2013) 122 (21): 2445.

https://doi.org/10.1182/blood.V122.21.2445.2445

Published: 2013

Journal Articles

Genomic Instability and Activation Of The DNA Damage Response Pathway Is An Independent Predictor Of Poor Prognosis, Is Associated With MYC Expression and Is a Promising Target For Therapy In Diffuse Large B Cell Lymphoma

Enrico Derenzini, MD, Claudio Agostinelli, MD, Ilaria Iacobucci, PhD, Enrica Imbrogno, Beatrice Casadei, MD, Giovanni Martinelli, MD, Stefano A Pileri, MD, Pier Luigi Zinzani, MD

Blood (2013) 122 (21): 3015.

https://doi.org/10.1182/blood.V122.21.3015.3015

Published: 2013

Journal Articles

Foxo3-Mediated Redox Regulation Is Required for DNA Damage Response in Hematopoietic Stem Cells.

Carolina L. Bigarella, PhD, Pauline Rimmele, PhD, Brigitte Izac, MSc, Valentina d'Escamard, MSc, Saghi Ghaffari, MD, PhD

Blood (2012) 120 (21): 2295.

https://doi.org/10.1182/blood.V120.21.2295.2295

Published: 2012

Journal Articles

Mef2C Maintains B Cell Homeostasis Through the Regulation of DNA Repair Machinery

Wenyuan Wang, Amelie Montel-Hagen, PhD, Rajkumar Sasidharan, PhD, Hanna K. A. Mikkola, MD, PhD

Blood (2012) 120 (21): 278.

https://doi.org/10.1182/blood.V120.21.278.278

Published: 2012

Journal Articles

Trisomy 8 Is Associated with Increased DNA Double Strand Breaks in Primary Myeloblasts

Meagan A Jacoby, MD/PhD, Rigoberto de Jesus, Matthew J. Walter, MD

Blood (2012) 120 (21): 3492.

https://doi.org/10.1182/blood.V120.21.3492.3492

Published: 2012

NARROW

Inhibition of BMP-Smad Pathway Reduces Leukemic Stemness in Pediatric AML

Preliminary Lasso Regression Analysis Identifies DNA-Damage Gene Expression Signature Predictive of Clinical Outcomes in Patients Using Gemtuzumab Ozogamicin

Bone Marrow Mesenchymal Stromal Cells and Inflammation Contribute to ETV6-RUNX1 + Preleukemic Cells Persistence and DNA Damaging

Dual Targeting of Cell-Cycle Checkpoint Kinase and Unfolded Protein Response As a Novel Therapeutic Approach for High-Risk Multiple Myeloma with TP53 Deletion or Mutations

Upregulation of Alternatively Glycosylated Smoothened (SMO) Is Involved in Doxorubicin (DXR) Resistance in Diffuse Large B-Cell Lymphoma

The Bone Marrow Environment Promotes Resistance to Mitoxantrone and Etoposide By Distinct Mechanisms in Pediatric AML

Inhibition of WEE1 Induces Cell Death of Both Bortezomib- and Lenalidomide-Resistant Multiple Myeloma Cells: A Novel Therapeutic Approach Targeting Cell-Cycle Checkpoint Kinase

The Role of UBR5 Mutations in the Pathogenesis of Mantle CELL Lymphoma

Age-Related Changes in the Interaction of Acute Myeloid Leukemia with the Bone Marrow Microenvironment Correlate with Response to Treatment and Survival: A Role for L-Selectin

The mTOR Inhibitor Everolimus Overcomes CXCR4-Mediated Resistance to HDAC Inhibitor Panobinostat through Inhibition of p21 and Mitosis Regulators, Sensitizing MM Cells to DNA-Damaged Induced Apoptosis

Molecular Mechanism and Optimal Treatment Strategy in Acute Myeloid Leukemia with Resistance to Drugs and Radiation By NVP-LED225

ANKHD1 Is Essential for Repair of DNA Double-Strand Breaks in Multiple Myeloma

Premature Senescence in Hematopoietic Stem and Progenitor Cells in Ribosomopathy-Associated Bone Marrow Failure Syndromes

A Novel Alkylating Agent Melphalan Flufenamide Ethyl Ester Induces an Irreversible DNA Damage in Multiple Myeloma Cells

Activation Induced Cytidine Deaminase-Associated DNA Repair Pathways Influence Germinal Center B Cell Lymphomagenesis

The Splicing Factor Heterogeneous Nuclear Ribonucleoprotein L (hnRNPL) Restricts p53 Dependent and p53 Independent Cell Death Pathways In Hematopoietic Stem Cells

Genomic Instability and Activation Of The DNA Damage Response Pathway Is An Independent Predictor Of Poor Prognosis, Is Associated With MYC Expression and Is a Promising Target For Therapy In Diffuse Large B Cell Lymphoma

Foxo3-Mediated Redox Regulation Is Required for DNA Damage Response in Hematopoietic Stem Cells.

Mef2C Maintains B Cell Homeostasis Through the Regulation of DNA Repair Machinery

Trisomy 8 Is Associated with Increased DNA Double Strand Breaks in Primary Myeloblasts

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American Society of Hematology

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ASH Publications

American Society of Hematology

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