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Journal Articles

GTx011, a Novel Agent That Improves Rheological Properties Of Sickle Cell Blood By Increasing Oxygen Affinity For Hemoglobin

Mira Patel, PhD, Donna Oksenberg, PhD, Abel Silva, BS, Andreas Betz, PhD, Brian Metcalf, PhD, Uma Sinha, PhD
Journal: Blood
Blood (2013) 122 (21): 2207.
https://doi.org/10.1182/blood.V122.21.2207.2207
Published: 2013
Journal Articles

A Phase 1, First-in-Man, Dose-Response Study of Aes-103 (5-HMF), an Anti-Sickling, Allosteric Modifier of Hemoglobin Oxygen Affinity in Healthy Norman Volunteers

Warren Stern, Ph.D., David Mathews, M.D., John McKew, Ph.D., Xiqgiang Shen, Ph.D., Gregory J. Kato, M.D.
Journal: Blood
Blood (2012) 120 (21): 3210.
https://doi.org/10.1182/blood.V120.21.3210.3210
Published: 2012
Journal Articles

Imaging Flow Cytometry for Fully Automated Quantification of Percentage of Sickled Cells in Sickle Cell Anemia.

Eduard J. van Beers, MD, PhD, Leigh Samsel, MS, Laurel G. Mendelsohn, M.S., Rehan Saiyed, BS, James S Nichols, RN, J. Philip McCoy, Jr., PhD, Gregory J. Kato, M.D.
Journal: Blood
Blood (2012) 120 (21): 2105.
https://doi.org/10.1182/blood.V120.21.2105.2105
Published: 2012
Journal Articles

NO or No NO, Increased Reduction of Nitrite to Nitric Oxide by Modified Red Blood Cells

Marcel H.A.M. Fens, PhD, Sandra K Larkin, Claudia R. Morris, MD, Bill Fitch, PhD, Jan Scicinski, PhD, Bryan Oronsky, MD, Frans A Kuypers, PhD
Journal: Blood
Blood (2011) 118 (21): 2125.
https://doi.org/10.1182/blood.V118.21.2125.2125
Published: 2011
Journal Articles

Various Drugs with or without an Antisickling Effect in the In Vitro Tests Showed a Strong Antisickling Effect in the In Vivo Studies in Transgenic Sickle Mice.

Toshio Asakura, MD, PhD, Osheiza Abdulmalik, DVM, Efe Iyamu, PhD, Qiukan Chen, MD, Jisheng Yang, Donald J. Abraham, PhD, Martin K. Safo, PhD, Carlo Brugnara, MD, Greg Evans, PhD
Journal: Blood
Blood (2005) 106 (11): 3190.
https://doi.org/10.1182/blood.V106.11.3190.3190
Published: 2005
Journal Articles

MSDD1, a Prodrug of 5-Hydroxymethyl-2-Furfural (5HMF), Prolongs the Antisickling Effect of 5HMF in Transgenic Sickle Mice.

Osheiza Abdulmalik, DVM, Martin K. Safo, PhD, Richmond Danso-Danquah, PhD, Jisheng Yang, Qiukan Chen, MD, Carlo Brugnara, MD, Donald J. Abraham, PhD, Toshio Asakura, MD, PhD
Journal: Blood
Blood (2004) 104 (11): 3576.
https://doi.org/10.1182/blood.V104.11.3576.3576
Published: 2004