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Journal Articles

MetAP2 Inhibition Modifies Hemoglobin S (HbS) to Delay Polymerization and Improve Blood Flow in Sickle Cell Disease

Melanie Demers, PhD, Sarah Sturtevant, BSc, Kevin Guertin, PhD, Dipti Gupta, Kunal Desai, MS, Benjamin Vieira, BS, Alexandra Hicks, PhD, Ayman Ismail, PhD, Yukio Nakamura, MD PhD, Bronner Goncalves, MD PhD, Giuseppe Di Caprio, PhD, Ethan Schonbrun, PhD, Scott Hansen, BS, Martin K. Safo, PhD, David K. Wood, PhD, John M. Higgins, MD PhD, David R. Light, PhD

Blood (2019) 134 (Supplement_1): 2260.

https://doi.org/10.1182/blood-2019-128727

Published: 2019

Journal Articles

Hematopoietic Stem Cells Increase Quiescence during Aging

Larisa V. Kovtonyuk, PhD, Peter Ashcroft, PhD, Gianluca Spaltro, MD, Nageswara Rao Tata, Radek C. Skoda, Sebastian Bonhoeffer, Markus G. Manz, Prof.Dr.MD

Blood (2019) 134 (Supplement_1): 2484.

https://doi.org/10.1182/blood-2019-130668

Published: 2019

Journal Articles

Analysis of Platelet Alpha and Dense Granule Release Using Small Volumes of Blood

Joseph Cho, MD PhD, Melissa Tjota, MD PhD, Jocelyn Gutierrez, BSMT, Krzysztof Mikrut, BSMT(ASCP), Geoffrey D. Wool, MD PhD, Jonathan L Miller, MD PhD

Blood (2019) 134 (Supplement_1): 2342.

https://doi.org/10.1182/blood-2019-131258

Published: 2019

Journal Articles

First Description of B Cell Maturation Antigen Expression in Light Chain Amyloidosis

Susan Bal, MDMBBS, Allison Sigler, Alexander Chan, MD, David J. Chung, MD PhD, Ahmet Dogan, MD PhD, Sergio A Giralt, MD, Hani Hassoun, MD, Heather J Landau, MD

Blood (2019) 134 (Supplement_1): 5452.

https://doi.org/10.1182/blood-2019-127332

Published: 2019

Journal Articles

Identification of Potent Quiescent Human Hematopoietic Stem Cells Using Mitochondrial Profile

Jiajing Qiu, PhD, Jana Gjini, Miao Lin, Msc, Tasleem Arif, PhD, Saghi Ghaffari, PhD MD

Blood (2019) 134 (Supplement_1): 5602.

https://doi.org/10.1182/blood-2019-129913

Published: 2019

Journal Articles

A Role for TNF-α in Chronic Lymphocytic Leukemia Bone Marrow Hematopoietic Dysfunction

Bryce A Manso, BSc, Jordan Krull, Kimberly Gwin, Petra Lothert, Charla R Secreto, Wei Ding, MD PhD, Sameer A. Parikh, MD, Anne J Novak, PhD, Neil E. Kay, MD, Kay L. Medina, PhD

Blood (2019) 134 (Supplement_1): 4276.

https://doi.org/10.1182/blood-2019-130518

Published: 2019

Journal Articles

S100A9 Contributes to T Cell Dysfunction through Its Interaction with RAGE in MDS

Wendy Kandell, BS, Thu Le Trinh, PhD, Xianghong Chen, PhD, Pingyan Cheng, MD, Danielle Gilvary, BS, Yin-Kai Chen, MD, Alexandra Calescibetta, Erika Adriana Eksioglu, MS PhD, Alan F. List, MD, Sheng Wei, MD

Blood (2019) 134 (Supplement_1): 4228.

https://doi.org/10.1182/blood-2019-128717

Published: 2019

Journal Articles

A Novel Sandwich ELISA to Quantify Erythroferrone in Mouse Serum

Patrick Gutschow, MS, Huiling Han, MD, Gordana Olbina, PhD, Keith Westerman, BS, Eileen Westerman, BS, Marc Ruiz Martinez, PhD, Yelena Ginzburg, MD, Elizabeta Nemeth, PhD, Tomas Ganz, MD PhD, Vaughn Ostland, PhD

Blood (2019) 134 (Supplement_1): 2237.

https://doi.org/10.1182/blood-2019-130947

Published: 2019

Journal Articles

DNA Cytosine-Demethylating Agent 5-Aza-2'-Deoxycytidine Targets Leukemia Cells through Reducing DNA N 6 -Methyladenine

Xiaochang Liu, PhD, Jiuxia Pang, Christopher Seiler, Ryan Kempen, Hao Liu, Aref Al-Kali, MD, Y. Natalia Tretyakova, Mark Litzow, MD, Shujun Liu

Blood (2019) 134 (Supplement_1): 2513.

https://doi.org/10.1182/blood-2019-130490

Published: 2019

Journal Articles

Growth Factor-Dependent Activation of a MYC-Induced Latent AML Program in Human Hematopoietic Cells

Elizabeth Bulaeva, Davide Pellacani, PhD, Naoto Nakamichi, MD PhD, Philip Beer, MD PhD, Colin Hammond, Alireza Lorzadeh, Michelle Moksa, Annaick Carles, Misha Bilenky, Sylvain Lefort, PhD, Jeremy Shu, Brian T. Wilhelm, PhDBSc, Andrew P. Weng, MD PhD, Martin Hirst, PhD, Connie J. Eaves, PhD

Blood (2019) 134 (Supplement_1): 2533.

https://doi.org/10.1182/blood-2019-122768

Published: 2019

Journal Articles

Comparison of RNA-Based Versus DNA-Based Quantitative KIT D816V Mutation Analysis Reveals Significant Disparity in Patients with Advanced Systemic Mastocytosis

Mohamad Jawhar, Nicole Naumann, Johannes Lübke, Juliana Schwaab, Oliver Hofmann, Thomas Kielsgaard Kristensen, Karl Sotlar, Verena Haselmann, Sven Schneider, Georgia Metzgeroth, Henning D. Popp, Alice Fabarius, PhD, Peter Bugert, Wolf-Karsten Hofmann, MD PhD, Andreas Reiter

Blood (2019) 134 (Supplement_1): 2955.

https://doi.org/10.1182/blood-2019-128811

Published: 2019

Journal Articles

Codanin-1 Mutations Engineered in Human Erythroid Cells Allow Investigation of Mechanisms Underlying Congenital Dyserythropoietic Anemia

Zachary C. Murphy, PhD, Michael Getman, MS, Jacquelyn Lillis, Laurie A. Steiner, MD

Blood (2019) 134 (Supplement_1): 3739.

https://doi.org/10.1182/blood-2019-127415

Published: 2019

Journal Articles

Robust Hematopoietic Stem Cell Function and Minimal Myeloid Skewing with Aging in Un-Separated Murine Whole Bone Marrow: What Are We Losing with Hematopoietic Stem Cell Purification?

Mark S Dooner, Elaine Papa, Michael Del Tatto, Mandy Pereira, Sicheng Wen, MD PhD, Yan Cheng, PhD, Peter J. Quesenberry, MD, Laura R Goldberg, MD PhD

Blood (2019) 134 (Supplement_1): 3723.

https://doi.org/10.1182/blood-2019-124367

Published: 2019

Journal Articles

Sirpαfc Treatment Targets Human Acute Myeloid Leukemia Stem Cells

Oleksandr Galkin, PhD, Jessica McLeod, BSc, James A Kennedy, MD PhD, Liqing Jin, MD, Nathan Mbong, Mark Wong, PhD, Bob Uger, PhD, Mark D. Minden, MD PhD, Jayne S Danska, PhD, Jean C.Y. Wang, MD

Blood (2019) 134 (Supplement_1): 3906.

https://doi.org/10.1182/blood-2019-131018

Published: 2019

Journal Articles

A Novel Cereblon E3 Ligase Modulator Eradicates Acute Myeloid Leukemia Stem Cells through Degradation of Translation Termination Factor GSPT1

Liqing Jin, MD, Nathan Mbong, Stanley W.K. Ng, PhD, Jean C.Y. Wang, MD, Mark D. Minden, MD PhD, Jinhong Fan, Daniel W. Pierce, Michael Pourdehnad, MD, John E. Dick, PhD

Blood (2019) 134 (Supplement_1): 3940.

https://doi.org/10.1182/blood-2019-128450

Published: 2019

Journal Articles

Latent Membrane Protein 1 Contributes to Deficient Cellular Immunity in NKTCL Patients

Xiaoyan Feng, Yue Song, Zhaoming Li, MD PhD, Xudong Zhang, Lugui Qiu, MD PhD, Mingzhi Zhang, MD PhD

Blood (2019) 134 (Supplement_1): 3969.

https://doi.org/10.1182/blood-2019-128622

Published: 2019

Journal Articles

Initial Findings of the Phase 1 Trial of PBCAR0191, a CD19 Targeted Allogeneic CAR-T Cell Therapy

Caron A. Jacobson, MD, Alex F. Herrera, MD, Lihua E Budde, MD PhD, Daniel J. DeAngelo, MD, Christopher Heery, MD, Anthony Stein, MD, Michael D. Jain, MD PhD, Bijal Shah, MD

Blood (2019) 134 (Supplement_1): 4107.

https://doi.org/10.1182/blood-2019-128203

Published: 2019

Journal Articles

RhoA Targeting Suppresses Cold-Induced Platelet Lesion and Allows Refrigerated Storage of Functional Human Platelets to Fourteen Days

Shailaja N Hegde, PhD, Huzoor Akbar, PhD, Shawnagay Nestheide, BS, Ashley M Wellendorf, B.S., Breanna Bohan, James F Johnson, Yi Zheng, PhD, Jose A Cancelas, MD

Blood (2019) 134 (Supplement_1): 99.

https://doi.org/10.1182/blood-2019-125359

Published: 2019

Journal Articles

Anti-CD6 Monoclonal Antibody Itolizumab Efficiently Inhibits T Cell Proliferation after in Vitro TCR Stimulation in the Setting of Acute Graft Versus Host Disease

Benedetta Rambaldi, MD, Carol Reynolds, PhD, Sharmila Chamling Rai, BSc, Takeru Asano, MD PhD, Yohei Arihara, MD PhD, Mahasweta Gooptu, MD, John Koreth, MBBS, DPhil, Corey Cutler, MD MPH, FRCPC, Sarah Nikiforow, MD PhD, Vincent T. Ho, MD, Edwin P. Alyea, III, MD, Joseph H. Antin, MD, Rizwan Romee, MD PhD, Robert J. Soiffer, MD, Domenico Russo, MD, Jeanette Ampudia, BSc, Cherie Tracy Ng, PhD MPH, Stephen Connelly, PhD MBA, Jerome Ritz, MD

Blood (2019) 134 (Supplement_1): 4517.

https://doi.org/10.1182/blood-2019-125721

Published: 2019

Journal Articles

Combination of NKTR-255, a Polymer Conjugated Human IL-15, with CD19 CAR T Cell Immunotherapy in a Preclinical Lymphoma Model

Cassie Chou, MD PhD, Simon Fraessle, Rachel Steinmetz, BSc, Reed M. Hawkins, BS, Tinh-Doan Phi, BS, Dirk Busch, Takahiro Miyazaki, Mario Q. Marcondes, MD PhD, Stanley R. Riddell, MD, Cameron J. Turtle, MBBS, PhD

Blood (2019) 134 (Supplement_1): 2866.

https://doi.org/10.1182/blood-2019-125960

Published: 2019

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MetAP2 Inhibition Modifies Hemoglobin S (HbS) to Delay Polymerization and Improve Blood Flow in Sickle Cell Disease

Hematopoietic Stem Cells Increase Quiescence during Aging

Analysis of Platelet Alpha and Dense Granule Release Using Small Volumes of Blood

First Description of B Cell Maturation Antigen Expression in Light Chain Amyloidosis

Identification of Potent Quiescent Human Hematopoietic Stem Cells Using Mitochondrial Profile

A Role for TNF-α in Chronic Lymphocytic Leukemia Bone Marrow Hematopoietic Dysfunction

S100A9 Contributes to T Cell Dysfunction through Its Interaction with RAGE in MDS

A Novel Sandwich ELISA to Quantify Erythroferrone in Mouse Serum

DNA Cytosine-Demethylating Agent 5-Aza-2'-Deoxycytidine Targets Leukemia Cells through Reducing DNA N 6 -Methyladenine

Growth Factor-Dependent Activation of a MYC-Induced Latent AML Program in Human Hematopoietic Cells

Comparison of RNA-Based Versus DNA-Based Quantitative KIT D816V Mutation Analysis Reveals Significant Disparity in Patients with Advanced Systemic Mastocytosis

Codanin-1 Mutations Engineered in Human Erythroid Cells Allow Investigation of Mechanisms Underlying Congenital Dyserythropoietic Anemia

Robust Hematopoietic Stem Cell Function and Minimal Myeloid Skewing with Aging in Un-Separated Murine Whole Bone Marrow: What Are We Losing with Hematopoietic Stem Cell Purification?

Sirpαfc Treatment Targets Human Acute Myeloid Leukemia Stem Cells

A Novel Cereblon E3 Ligase Modulator Eradicates Acute Myeloid Leukemia Stem Cells through Degradation of Translation Termination Factor GSPT1

Latent Membrane Protein 1 Contributes to Deficient Cellular Immunity in NKTCL Patients

Initial Findings of the Phase 1 Trial of PBCAR0191, a CD19 Targeted Allogeneic CAR-T Cell Therapy

RhoA Targeting Suppresses Cold-Induced Platelet Lesion and Allows Refrigerated Storage of Functional Human Platelets to Fourteen Days

Anti-CD6 Monoclonal Antibody Itolizumab Efficiently Inhibits T Cell Proliferation after in Vitro TCR Stimulation in the Setting of Acute Graft Versus Host Disease

Combination of NKTR-255, a Polymer Conjugated Human IL-15, with CD19 CAR T Cell Immunotherapy in a Preclinical Lymphoma Model

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American Society of Hematology

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