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Journal Articles

Oncogenic Nras Grants Apoptosis Resistance to Hematopoietic Stem Cells

Kevin B Yang, Victor Ng, MS, Gina Ney, MD PhD, Lu Liu, PhD, Xi Jin, PhD, Qing Li, MD PhD

Blood (2015) 126 (23): 2451.

https://doi.org/10.1182/blood.V126.23.2451.2451

Published: 2015

Journal Articles

A Subpopulation of Blasts with Attenuated p38 MAPK Response Is Seen in Virtually All AML Patients and AML Cell Lines and Is Defined By Cells with Augmented Lipid-Associated Anti-Oxidant Defense

Paul S. Hole, PhD, Sara Davies, MSc, Chinmay R Munje, BSc PhD, Sandra Kreuser, BSc, Robert K. Hills, MA MSc DPhil, Nader Omidvar, PhD, Steven Knapper, DM BMBCh, Alan K. Burnett, MDFRCP, Alex Tonks, BSc PhD, Richard L. Darley, BSc PhD

Blood (2014) 124 (21): 785.

https://doi.org/10.1182/blood.V124.21.785.785

Published: 2014

Journal Articles

Arsenic Trioxide Resistance: More to It Than Mutations in PML-RARα

Ansu Abu Alex, MSc, Ezhilarasi Chendamarai, PhD, Saravanan Ganesan, MSc, Nithya Balasundaram, MSc, Hamenth Kumar Palani, MSc, Sachin David, MSc, Vikram Mathews, MD

Blood (2014) 124 (21): 3605.

https://doi.org/10.1182/blood.V124.21.3605.3605

Published: 2014

Journal Articles

The Rheumatoid Arthritis Drug Auranofin Has Significant in Vitro Activity in MCL and DLCL and Is Synergistic with a Glutathione Depleting Agent

Jolanta Skalska, PhD, Michelle M. Kiebala, PhD, Shannon P. Hilchey, PhD, Yun Dai, MD, PhD, Steven Grant, MD, Paul S. Brookes, PhD, Derick R. Peterson, PhD, Sanjay B. Maggirwar, PhD, Steven H. Bernstein, MD

Blood (2012) 120 (21): 1658.

https://doi.org/10.1182/blood.V120.21.1658.1658

Published: 2012

Journal Articles

Glutathione Depletion Enhances Arsenic Trioxide-Induced Apoptosis in Lymphoma Cells through Mitochondrial and Caspase-Independent Mechanisms.

Savita Bhalla, PhD, Leo I. Gordon, MD, Amareshwar Singh, PhD, Sheila Prachand, M.S., Shuo Yang, PhD, Jane N. Winter, MD, Dongsheng Guo, PhD, Thomas O'Halloran, PhD, Leonidas C Platanias, Andrew M. Evens, DO, MSc

Blood (2009) 114 (22): 2708.

https://doi.org/10.1182/blood.V114.22.2708.2708

Published: 2009

Journal Articles

Mitochondrial-Mediated Apoptosis in Lymphoma by the Diterpenoid Lactone Andrographolide (Andro), the Active Component of Andrographolis Paniculata.

Shuo Yang, PhD, Andrew M Evens, DO, MSc, Savita Bhalla, PhD, Sheila Prachand, M.S., Amareshwar Singh, PhD, Leo I. Gordon, MD

Blood (2009) 114 (22): 2710.

https://doi.org/10.1182/blood.V114.22.2710.2710

Published: 2009

Journal Articles

Activation of TAO2 Kinase by Arsenic Trioxide in Leukemic Cells

Jennifer L. McNeer, MD, Blazej Dolniak, PhD, Barbara Kroczynska, PhD, Antonella Sassano, PhD, Leonidas Platanias, MD, PhD

Blood (2008) 112 (11): 5324.

https://doi.org/10.1182/blood.V112.11.5324.5324

Published: 2008

Journal Articles

The Diterpenoid Lactone Andrographolide (ANDRO) Stimulates Autophagy and Induces Reactive Oxygen Species (ROS)-Dependent Apoptosis in Lymphoma Cell Lines

Shuo Yang, PhD, Andrew M. Evens, DO, MS, Sheila Prachand, MS, Leo I. Gordon, MD

Blood (2008) 112 (11): 4991.

https://doi.org/10.1182/blood.V112.11.4991.4991

Published: 2008

Journal Articles

Unique Resistance Mechanism to Dexamethasone by Glutathione S-Transferase M1 Involving p38 MAPK and NF-κB Pathways, Possible Prognostic Role for Childhood ALL.

Naoko Hosono, MD, Shinji Kishi, MD., PhD., Sumiko Iho, PhD., Yoshimasa Urasaki, MD., PhD., Akira Yoshida, MD., PhD., Hisanori Kurooka, PhD., Yoshifumi Yokota, MD., PhD., Takanori Ueda, MD., PhD.

Blood (2007) 110 (11): 2375.

https://doi.org/10.1182/blood.V110.11.2375.2375

Published: 2007

Journal Articles

Induction of Oxidative Stress and Glutathione Depletion by ABT-737, a Novel Small Molecule Inhibitor of Bcl-2, Contributes to Cytotoxicity in Leukemia Cells.

Joya Chandra, PhD, Adrienne Howard, Kathleen Jensen, Ray Meyn, Ph.D.

Blood (2007) 110 (11): 4336.

https://doi.org/10.1182/blood.V110.11.4336.4336

Published: 2007

Journal Articles

Inactivation of p38 MAPK Extends Self-Renewal Capacity of Haematopoietic Stem Cells.

Keisuke Ito, MD, PhD, Atsushi Hirao, MD, PhD, Fumio Arai, DD, PhD, Sahoko Matsuoka, MD, PhD, Keiyo Takubo, MD, Yasuo Ikeda, MD, PhD, Toshio Suda, MD, PhD

Blood (2005) 106 (11): 265.

https://doi.org/10.1182/blood.V106.11.265.265

Published: 2005

Journal Articles

Proteinated Elemental Selenium Potentiates Anti-Tumor Effect of Ionizing Radiation and Chemotherapeutic Agents but Is Only Minimally Affected by Drug Resistance Mechanisms.

Ichiro Tsujino, MD PhD, Kiyoko Miyagi, MD PhD, Reynee W. Sampson, MS, Wolfgang H.H. Gunther, PhD, Marianne Krieg, PhD, Fritz Sieber, PhD

Blood (2004) 104 (11): 4367.

https://doi.org/10.1182/blood.V104.11.4367.4367

Published: 2004

Journal Articles

Arsenic Trioxide and Ascorbic Acid Enhances the Cytotoxicity of Hu1D10 towards CLL Cells.

Sabyasachi Biswas, PhD, Andrew P. Mone, MD, PhD, Chandan K. Sen, PhD, Natarajan Muthusamy, PhD, John C. Byrd, MD

Blood (2004) 104 (11): 3479.

https://doi.org/10.1182/blood.V104.11.3479.3479

Published: 2004

NARROW

Oncogenic Nras Grants Apoptosis Resistance to Hematopoietic Stem Cells

A Subpopulation of Blasts with Attenuated p38 MAPK Response Is Seen in Virtually All AML Patients and AML Cell Lines and Is Defined By Cells with Augmented Lipid-Associated Anti-Oxidant Defense

Arsenic Trioxide Resistance: More to It Than Mutations in PML-RARα

The Rheumatoid Arthritis Drug Auranofin Has Significant in Vitro Activity in MCL and DLCL and Is Synergistic with a Glutathione Depleting Agent

Glutathione Depletion Enhances Arsenic Trioxide-Induced Apoptosis in Lymphoma Cells through Mitochondrial and Caspase-Independent Mechanisms.

Mitochondrial-Mediated Apoptosis in Lymphoma by the Diterpenoid Lactone Andrographolide (Andro), the Active Component of Andrographolis Paniculata.

Activation of TAO2 Kinase by Arsenic Trioxide in Leukemic Cells

The Diterpenoid Lactone Andrographolide (ANDRO) Stimulates Autophagy and Induces Reactive Oxygen Species (ROS)-Dependent Apoptosis in Lymphoma Cell Lines

Unique Resistance Mechanism to Dexamethasone by Glutathione S-Transferase M1 Involving p38 MAPK and NF-κB Pathways, Possible Prognostic Role for Childhood ALL.

Induction of Oxidative Stress and Glutathione Depletion by ABT-737, a Novel Small Molecule Inhibitor of Bcl-2, Contributes to Cytotoxicity in Leukemia Cells.

Inactivation of p38 MAPK Extends Self-Renewal Capacity of Haematopoietic Stem Cells.

Proteinated Elemental Selenium Potentiates Anti-Tumor Effect of Ionizing Radiation and Chemotherapeutic Agents but Is Only Minimally Affected by Drug Resistance Mechanisms.

Arsenic Trioxide and Ascorbic Acid Enhances the Cytotoxicity of Hu1D10 towards CLL Cells.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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