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Reduced Intensity Delayed Intensification in Standard-Risk Patients Defined By Minimal Residual Disease in Childhood Acute Lymphoblastic Leukemia: Results of an International Randomized Trial in 1164 Patients (Trial AIEOP-BFM ALL 2000)

Martin Schrappe, MD, Martin Zimmermann, PhD, Anja Möricke, MD, Georg Mann, MD, Maria Grazia Valsecchi, PhD, Claus R. Bartram, PhD, Andrea Biondi, MD, Renate Panzer-Grümayer, MD, Rita Beier, MD, Gunnar Cario, Franco Locatelli, MD, Giuseppe Basso, Felix Niggli, MD, Maurizio Aricò, MD, Valentino Conter
Journal: Blood
Blood (2016) 128 (22): 4.
https://doi.org/10.1182/blood.V128.22.4.4
Published: 2016
Journal Articles

Delayed Intensification (DI) Enhances Event-Free Survival (EFS) of Children with B-Precursor Acute Lymphoblastic Leukemia (ALL) Who Received Intensification Therapy with Six Courses of Intravenous Methotrexate (MTX): POG 9904/9905: A Childrens Oncology Group Study (COG).

Naomi Winick, MD, Paul L. Martin, MD, PhD, Meenakshi Devidas, PhD, Jonathan Shuster, PhD, Michael J. Borowitz, MD, PhD, Paul Bowman, MD, Eric Larsen, MD, Jeanette Pullen, MD, Stephen P. Hunger, MD, William L. Carroll, MD, Bruce M. Camitta, MD
Journal: Blood
Blood (2007) 110 (11): 583.
https://doi.org/10.1182/blood.V110.11.583.583
Published: 2007
Journal Articles

Treatment Intensification of Traditional BFM Therapy with 3 Chemotherapy Blocks and Double Delayed Intensification (Protocol II) Improves Outcome in Infants with High Risk (HR) Acute Lymphoblastic Leukemia (ALL): Results of Two Consecutive AIEOP Studies.

Carmelo Rizzari, Maria Grazia Valsecchi, Paola De Lorenzo, Maurizio Aricò, Giuseppe Basso, Franco Locatelli, Luca Lo Nigro, Giulio De Rossi, Giuseppe Masera, Andrea Biondi
Journal: Blood
Blood (2005) 106 (11): 871.
https://doi.org/10.1182/blood.V106.11.871.871
Published: 2005
Journal Articles

Improved outcome in high-risk childhood acute lymphoblastic leukemia defined by prednisone-poor response treated with double Berlin-Frankfurt-Muenster protocol II

Clinical Trials & Observations
Maurizio Aricò, Maria Grazia Valsecchi, Valentino Conter, Carmelo Rizzari, Andrea Pession, Chiara Messina, Elena Barisone, Vincenzo Poggi, Giulio De Rossi, Franco Locatelli, Maria Concetta Micalizzi, Giuseppe Basso, Giuseppe Masera
Journal: Blood
Blood (2002) 100 (2): 420–426.
https://doi.org/10.1182/blood.V100.2.420
Published: 2002