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Journal Articles

Cost-Effectiveness of Avatrombopag for the Treatment of Thrombocytopenia in Patients with Chronic Liver Disease

Lee F. Allen, MD PhD, Kavita Aggarwal, PharmD, Michael Vredenburg, PhD, Christine Barnett, PhD, Deirdre Mladsi, BA, Ray Kim, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3454.
https://doi.org/10.1182/blood-2019-131822
Published: 2019
Journal Articles

Long-Term Response Rates in Patients with Chronic Immune Thrombocytopenia Treated with Avatrombopag: Additional Analyses from a Phase 3 Study and Its Extension Phase

Hanny Al-Samkari, MD, Kavita Aggarwal, PharmD, Michael Vredenburg, PhD, Wei Tian, PhD, Lee F. Allen, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2356.
https://doi.org/10.1182/blood-2019-131215
Published: 2019
Journal Articles

Platelet Response to Avatrombopag in Patients with Chronic Immune Thrombocytopenia: Additional Analyses from a Phase 3 Study and Its Extension

Srikanth Nagalla, MBBS,MS, Michael Vredenburg, PhD, Wei Tian, PhD, Lee F. Allen, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1071.
https://doi.org/10.1182/blood-2019-130963
Published: 2019
Journal Articles

A Systematic Review and Meta-Analysis of Safety and Efficacy for Pre-Procedural Use of Thrombopoietin Receptor Agonists in Hepatic Cirrhosis Patients

Kunhwa Kim, MDMPH, Faustine Ong, Gabor Varadi, MD, Sorab Gupta, MD, Vinicius Machado Jorge, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1094.
https://doi.org/10.1182/blood-2019-132063
Published: 2019
Journal Articles

Absence of Plasma Gastric Biomarker Elevations with Chronic Dosing of Avatrombopag, a Novel Oral Thrombopoietin Receptor Agonist, in Patients with Chronic Immune Thrombocytopenia in Phase 3 Trials

James B. Bussel, MD, Lee F. Allen, MD PhD, Wei Tian, PhD, David J. Kuter, MD DPhil
Journal: Blood
Blood (2018) 132 (Supplement 1): 3740.
https://doi.org/10.1182/blood-2018-99-116873
Published: 2018
Journal Articles

Platelet Function in Thrombocytopenic Patients with Chronic Liver Disease

Elena Smolensky Koganov, PhD, Sabrina L Carmichael, BS, Emma E Forde, BS, Andrew L Frelinger, III, PhD, Alan D Michelson, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2314.
https://doi.org/10.1182/blood.V130.Suppl_1.2314.2314
Published: 2017
Journal Articles

Avatrombopag, a Novel Thrombopoietin Receptor Agonist, Increases Platelet Counts without Increasing Platelet Activation in Patients with Thrombocytopenia Due to Chronic Liver Disease

Andrew L Frelinger, III, PhD, Elena Smolensky Koganov, PhD, Emma E Forde, BS, Sabrina L Carmichael, BS, Alan D Michelson, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 290.
https://doi.org/10.1182/blood.V130.Suppl_1.290.290
Published: 2017
Journal Articles

Avatrombopag, a Novel Oral Thrombopoietin Receptor Agonist, Demonstrates Superiority to Placebo for the Treatment of Chronic Immune Thrombocytopenic Purpura in a Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial

Wojciech Jurczak, PhDMD, Krzysztof Chojnowski, MD, Jiri Mayer, Prof, MD SCs, Katarzyna Krawczyk, MD PhD, Francesco Bibbiani, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 17.
https://doi.org/10.1182/blood.V130.Suppl_1.17.17
Published: 2017
Journal Articles

Superiority of Avatrombopag to Placebo in Increasing Platelet Counts in Patients with Chronic Liver Disease-Associated Thrombocytopenia Undergoing Scheduled Procedures: Results from 2, Phase 3 Randomized Studies

Norah Terrault, MD MPH, David J Kuter, MD DPhil, Namiki Izumi, MD PhD, Zeid Kayali, MD, Paul Mitrut, MD PhD, Won Young Tak, MD, Francesco Bibbiani, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 18.
https://doi.org/10.1182/blood.V130.Suppl_1.18.18
Published: 2017
Journal Articles

Effects of Anti-Glycoprotein Antibodies on Response of Immune Thrombocytopenia Patients to Thrombopoietin Receptor Agonists and on Megakaryocytes Viability

Marina Izak Karaev, MD, Alexandra Kruse, Margaret Morrisey, Heyu Ni, MD PhD, Zhu Guangheng, Petra Pham, MS, W. Beau Mitchell, MD, James B Bussel, MD
Journal: Blood
Blood (2015) 126 (23): 1048.
https://doi.org/10.1182/blood.V126.23.1048.1048
Published: 2015
Journal Articles

A randomized trial of avatrombopag, an investigational thrombopoietin-receptor agonist, in persistent and chronic immune thrombocytopenia

Clinical Trials & Observations
James B. Bussel, David J. Kuter, Louis M. Aledort, Craig M. Kessler, Adam Cuker, Kelly B. Pendergrass, Shande Tang, Joe McIntosh
Journal: Blood
Blood (2014) 123 (25): 3887–3894.
https://doi.org/10.1182/blood-2013-07-514398
Published: 2014
Includes: Supplemental data