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Journal Articles

Concentration-QTc (C-QTc) Analysis of the MDM2 Inhibitor KRT-232 (formerly AMG 232) in Subjects with Advanced Solid Tumors, Multiple Myeloma, or Acute Myeloid Leukemia

Adekemi Taylor, PhD, Martine Allard, PhD, Cecile Kresja, PhD, Dana Lee, PharmD, Greg Slatter, PhD

Blood (2019) 134 (Supplement_1): 5768.

https://doi.org/10.1182/blood-2019-131481

Published: 2019

Journal Articles

Overall Survival (OS) Benefit of Oral Ixazomib in Combination with Lenalidomide and Dexamethasone (IRd) Vs Lenalidomide and Dexamethasone (Rd) in Asian Patients (pts) with Relapsed and/or Refractory Multiple Myeloma (RRMM): Pooled-Analysis from the Tourmaline-MM1 and the China Continuation Studies

Blood (2018) 132 (Supplement 1): 5637.

https://doi.org/10.1182/blood-2018-99-116844

Published: 2018

Journal Articles

Skin Blood Flow Measured By LSCI Demonstrates Treatment Effect of Chronic Transfusion Protocol in Sickle Cell Disease

Nicolas V Currier, MD PhD, Gersham Dent, PhD, Paul S. Swerdlow, MD, Willem Birkhoff, MD, Jacobus Burggraaf, MD PhD, Jaspert de Vries, Bsc, Jaladhar Neelavalli, PhD, Muhammad Shahid, MD, Brijesh K Yadav, MS, William E. Hobbs, MD PhD, Ajay Verma, MD PhD

Blood (2016) 128 (22): 4871.

https://doi.org/10.1182/blood.V128.22.4871.4871

Published: 2016

Journal Articles

Pharmacokinetic Profile and Pharmacodynamic Effects of ASP2215, a Selective, Potent Inhibitor of FLT3/AXL, in Patients with Relapsed or Refractory Acute Myeloid Leukemia: Results from a First-in-Human Phase 1/2 Study

Catherine C. Smith, MD, Mark J. Levis, MD PhD, Mark R Litzow, MD, Alexander E. Perl, MD, Jessica K. Altman, MD, Stanley C. Gill, PhD, Takeshi Kadokura, PhD, Geoffrey J. Yuen, Pharm.D., Ogert Fisniku, MS, Charles Liu, PhD, Itsuro Nagase, PhDDVM, Briana Sargent, BS, Noreen Welter, RN, BSN, Erkut Bahceci, MD

Blood (2015) 126 (23): 4836.

https://doi.org/10.1182/blood.V126.23.4836.4836

Published: 2015

Journal Articles

Phase IIa Study of the Anti-CXCL12/SDF-1 Spiegelmer® Nox-A12 Alone and Combined with Bendamustine/Rituximab in Patients with Relapsed Chronic Lymphocytic Leukemia (CLL)

Marco Gobbi, MD, Federico Caligaris-Cappio, MD, Marco Montillo, MD, Stephanie Vauléon, PhD, Stefan Zöllner, PhD, Thomas Dümmler, PhD, Anna Kruschinski, PhD, Frank Fliegert, MD

Blood (2012) 120 (21): 4593.

https://doi.org/10.1182/blood.V120.21.4593.4593

Published: 2012

Journal Articles

Single Oral Doses of a Novel Thrombopoietin Mimetic ONO-7746 Increase Platelet Counts In Healthy Subjects

Thomas L Hunt, MD, Ph.D, Ming Q. Lu, MD, PhD, Yasushi Kawasaki, MS, John P. Hall, BS, MBA, Junji Komaba, Ph.D, Masahiro Takeuchi, MS, Takuya Imamura, MS, David J. Kuter, MD, DPhil

Blood (2011) 118 (21): 4827.

https://doi.org/10.1182/blood.V118.21.4827.4827

Published: 2011

Journal Articles

A Double-Blind, Placebo-Controlled, and Multiple Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Ono-7746 in Healthy Subjects

Thomas L Hunt, MD, Ph.D, Ming Q. Lu, MD, PhD, Yasushi Kawasaki, MS, John P. Hall, BS, MBA, Junji Komaba, Ph.D, Masahiro Takeuchi, MS, Takuya Imamura, MS, David J. Kuter, MD, DPhil

Blood (2011) 118 (21): 4828.

https://doi.org/10.1182/blood.V118.21.4828.4828

Published: 2011

Journal Articles

Prolonged QTc Interval Is Common In Patients with Sickle Cell Disease and Has An Inverse Relationship to Hemoglobin and Hematocrit: Results From CSSCD

Ruchika Goel, MD, MPH, Sudha Rajderkar, MS, Rema Padman, PhD, Lakshmanan Krishnamurti, MD

Blood (2010) 116 (21): 2675.

https://doi.org/10.1182/blood.V116.21.2675.2675

Published: 2010

Journal Articles

Inhibition of Interleukin-6 (IL-6) Reverses Anemia In Patients with Advanced Non Small Cell Lung Cancer (NSCLC): Results of a Phase II, Randomized, Double-Blind, Placebo-Controlled Trial

Michael W. Schuster, MD, James R Rigas, MD, Sergey V Orlov, MD, Branislav Milovanovic, MD, Kumar Prabhash, Jeffrey T Smith, MD

Blood (2010) 116 (21): 640.

https://doi.org/10.1182/blood.V116.21.640.640

Published: 2010

Journal Articles

Electrocardiographic Screening for Cardiac Iron in Thalassemia Major.

Jon A. Detterich, MD, Janelle Miller, BS, Thomas D. Coates, MD, PhD, John C. Wood, MD, PhD

Blood (2007) 110 (11): 2766.

https://doi.org/10.1182/blood.V110.11.2766.2766

Published: 2007

Journal Articles

Corrected QT Interval Is Related to Markers of Hemolysis and Tricuspid Regurgitant Jet Velocity in a Young Cohort with Sickle Cell Disease.

Robert I. Liem, MD, Luciana T. Young, MD, Alexis A. Thompson, MD, MPH

Blood (2007) 110 (11): 2258.

https://doi.org/10.1182/blood.V110.11.2258.2258

Published: 2007

Journal Articles

Platelet Activation Promotes Formation of Platelet-Leukocyte Conjugates (PLC) in Non-Valvular Atrial Fibrillation (AF).

Aurelio Castrellon, MD, Julio A. Chirinos, MD, Juan P. Zambrano, MD, Wenche Jy, PhD, Lawrence L. Horstmann, MS, Eugene R. Ahn, MD, Joaquin J. Jimenez, MD, Howard Willens, MD, Agustin Castellanos, MD, Robert J. Myerburg, MD, Yeon S. Ahn, MD

Blood (2004) 104 (11): 3513.

https://doi.org/10.1182/blood.V104.11.3513.3513

Published: 2004

NARROW

Concentration-QTc (C-QTc) Analysis of the MDM2 Inhibitor KRT-232 (formerly AMG 232) in Subjects with Advanced Solid Tumors, Multiple Myeloma, or Acute Myeloid Leukemia

Overall Survival (OS) Benefit of Oral Ixazomib in Combination with Lenalidomide and Dexamethasone (IRd) Vs Lenalidomide and Dexamethasone (Rd) in Asian Patients (pts) with Relapsed and/or Refractory Multiple Myeloma (RRMM): Pooled-Analysis from the Tourmaline-MM1 and the China Continuation Studies

Skin Blood Flow Measured By LSCI Demonstrates Treatment Effect of Chronic Transfusion Protocol in Sickle Cell Disease

Pharmacokinetic Profile and Pharmacodynamic Effects of ASP2215, a Selective, Potent Inhibitor of FLT3/AXL, in Patients with Relapsed or Refractory Acute Myeloid Leukemia: Results from a First-in-Human Phase 1/2 Study

Phase IIa Study of the Anti-CXCL12/SDF-1 Spiegelmer® Nox-A12 Alone and Combined with Bendamustine/Rituximab in Patients with Relapsed Chronic Lymphocytic Leukemia (CLL)

Single Oral Doses of a Novel Thrombopoietin Mimetic ONO-7746 Increase Platelet Counts In Healthy Subjects

A Double-Blind, Placebo-Controlled, and Multiple Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Ono-7746 in Healthy Subjects

Prolonged QTc Interval Is Common In Patients with Sickle Cell Disease and Has An Inverse Relationship to Hemoglobin and Hematocrit: Results From CSSCD

Inhibition of Interleukin-6 (IL-6) Reverses Anemia In Patients with Advanced Non Small Cell Lung Cancer (NSCLC): Results of a Phase II, Randomized, Double-Blind, Placebo-Controlled Trial

Electrocardiographic Screening for Cardiac Iron in Thalassemia Major.

Corrected QT Interval Is Related to Markers of Hemolysis and Tricuspid Regurgitant Jet Velocity in a Young Cohort with Sickle Cell Disease.

Platelet Activation Promotes Formation of Platelet-Leukocyte Conjugates (PLC) in Non-Valvular Atrial Fibrillation (AF).

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American Society of Hematology

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American Society of Hematology

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