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Journal Articles

The Novel Human Double Minute (HDM)-2 Inhibitor DS-5272 Is Active Both Alone, and In Combination With Other Novel Agents, Against Multiple Myeloma

Dongmin Gu, M.D., Ph.D., Hua Wang, Ph.D., Zhiqiang Wang, Ph.D., Richard E. Davis, M.D., Shengli Cai, M.D., Ph.D., Takahiko Seki, Ph.D., Archie Tse, M.D., Ph.D., Robert Z. Orlowski, M.D., Ph.D

Blood (2013) 122 (21): 1927.

https://doi.org/10.1182/blood.V122.21.1927.1927

Published: 2013

Journal Articles

Bruton′s Tyrosine Kinase Inhibitor Ibrutinib Interferes With Constitutive and Induced Pre-B Cell Receptor Signaling In B-Cell Acute Lymphoblastic Leukemia

Ekaterina Kim, MS, Stefan Koehrer, MD, Nathalie Y. Rosin, PhD, Zhiqiang Wang, Ph.D., Deborah A. Thomas, MD, Farhad Ravandi, MD, Steven M. Kornblau, MD, Hagop M. Kantarjian, MD, Susan O'Brien, MD, Zeev Estrov, MD, Joseph J. Buggy, PhD, Markus Muschen, MD, PhD, Richard E. Davis, MD, Jan A. Burger, MD, PhD

Blood (2013) 122 (21): 1399.

https://doi.org/10.1182/blood.V122.21.1399.1399

Published: 2013

Journal Articles

The PI3K Delta Inhibitor Idelalisib Interferes With Pre-B Cell Receptor Signaling In Acute Lymphoblastic Leukemia (ALL): A New Therapeutic Concept

Nathalie Y. Rosin, PhD, Ekaterina Kim, MS, Stefan Koehrer, MD, Zhiqiang Wang, Ph.D., Susan O'Brien, MD, William G. Wierda, MD, Deborah A. Thomas, MD, Zeev Estrov, MD, Hagop M. Kantarjian, MD, Brian Lannutti, PhD, Richard E. Davis, PhD, Jan A. Burger, MD, PhD

Blood (2013) 122 (21): 2632.

https://doi.org/10.1182/blood.V122.21.2632.2632

Published: 2013

Journal Articles

Expression Of Truncated Protein Tyrosine Phosphatase, Receptor Type, O (PTPROt) Influences Multiple Myeloma Sensitivity To Bortezomib Through Akt Signaling, and Is a Favorable Clinical Prognostic Factor

Hua Wang, Ph.D., Veerabhadran Baladandayuthapani, Ph.D., Zhiqiang Wang, Ph.D., Jiexin Zhang, Heather Yan Lin, Ph.D., Richard E. Davis, M.D., Lin Yang, Robert Z. Orlowski, M.D., Ph.D.

Blood (2013) 122 (21): 2520.

https://doi.org/10.1182/blood.V122.21.2520.2520

Published: 2013

Journal Articles

CX-5461, a Novel RNA Polymerase I Inhibitor, Is Active Against Wild-Type and Mutant p53 Myeloma Models

Hans C. Lee, MD, Hua Wang, Ph.D., Bing-Zong Li, M.D., Ph.D., Zhiqiang Wang, Ph.D., Richard Julian Jones, Ph.D., Dongmin Gu, M.D., Ph.D., Sean O'Brien, Ph.D., Richard E. Davis, M.D., Robert Z. Orlowski, M.D., Ph.D.

Blood (2013) 122 (21): 4438.

https://doi.org/10.1182/blood.V122.21.4438.4438

Published: 2013

Journal Articles

Pre-BCR Signaling Activity Predicts Sensitivity To Syk Kinase Inhibition In B Cell Acute Lymphoblastic Leukemia (B-ALL)

Stefan Koehrer, MD, Richard E. Davis, M.D., Greg Coffey, PhD, Ekaterina Kim, MS, Nathalie Y. Rosin, PhD, Elisa ten Hacken, Susan O'Brien, MD, William G. Wierda, MD, PhD, Zeev Estrov, MD, Deborah A. Thomas, MD, Hagop M. Kantarjian, MD, Zhiqiang Wang, Ph.D., Hassan Jumaa, PhD, Jan A. Burger, MD, PhD

Blood (2013) 122 (21): 614.

https://doi.org/10.1182/blood.V122.21.614.614

Published: 2013

Journal Articles

Unique Effects of p53 −/− Leukemic Cells On Mesenchymal Stromal Cell Gene Expression Profile in Vitro

Xiaoyang Ling, PhD, Ye Chen, PhD, Peter P. Ruvolo, PhD, Vivian Ruvolo, Zhiqiang Wang, Ph.D., Min Zhang, Ph.D., Yuexi Shi, Marina Konopleva, MD, PhD, Richard E Davis, MD, Michael Andreeff, MD, PhD

Blood (2012) 120 (21): 3468.

https://doi.org/10.1182/blood.V120.21.3468.3468

Published: 2012

Journal Articles

NF-κB Activation in Mesenchymal Stromal Cells Mediates Leukemia Cell Chemoresistance

Rodrigo Jacamo, Ph.D, Ye Chen, PhD, Zhiqiang Wang, Ph.D., Wencai Ma, Ph.D., Min Zhang, Ph.D., Venkata L Battula, Ph.D., Wendy D. Schober, MLT (ASCP), Richard E Davis, MD, Marina Konopleva, MD, PhD, Michael Andreeff, MD, PhD

Blood (2012) 120 (21): 3518.

https://doi.org/10.1182/blood.V120.21.3518.3518

Published: 2012

Journal Articles

Activation of T and NK Cells Following Lenalidomide Therapy in Patients with Follicular Lymphoma.

Seema Rawal, PhD, Nathan Fowler, MD, Min Zhang, Ph.D., Zhiqiang Wang, Ph.D., Tariq Muzzafar, MBBS, Nusrat Harun, MS, Veerabhadran Baladandayuthapani, Ph.D., Rakesh Sharma, Ph.D, David Delgado, Michael Wallace, MD, Carla Heise, PhD, Linda Catherine Lacerte, RN, Felipe Samaniego, M.D., R Eric Davis, M.D, Sattva S. Neelapu, MD

Blood (2012) 120 (21): 2766.

https://doi.org/10.1182/blood.V120.21.2766.2766

Published: 2012

Journal Articles

Prognostic Impact and Targeting of CRM1 in Acute Myeloid Leukemia

Kensuke Kojima, MD, PhD, Steven M. Kornblau, MD, PhD, Vivian Ruvolo, Seshagiri Duvvuri, Richard E Davis, MD, Min Zhang, Ph.D., Zhiqiang Wang, Ph.D., Kevin R. Coombes, PhD, Nianxiang Zhang, Yi Hua Qiu, MD, Jared K. Burks, Peter P. Ruvolo, PhD, Sharon Shacham, PhD MBA, Michael Kauffman, MD, Ph.D., Michael Andreeff, MD, PhD

Blood (2012) 120 (21): 870.

https://doi.org/10.1182/blood.V120.21.870.870

Published: 2012

Journal Articles

PD-1 + T Cell Subsets in Follicular Lymphoma Tumor Microenvironment and Their Implications for Prognosis and Therapy

Fuliang Chu, PhD, Wencai Ma, Ph.D., Tomohide Yamazaki, Myriam Foglietta, MD, Durga Nattama, Seema Rawal, PhD, Zhiqiang Wang, Ph.D., Yanli Gao, Natalia M Orozco, Luis Vence, Laszlo Radvanyi, Chen Dong, PhD, Richard Eric Davis, MD, Sattva S. Neelapu, MD

Blood (2011) 118 (21): 2648.

https://doi.org/10.1182/blood.V118.21.2648.2648

Published: 2011

Journal Articles

Connective Tissue Growth Factor (CTGF) Is Essential for Self Renewal and Proliferation of Mesenchymal Stromal Cells (MSCs) and Affects Leukemia-Stromal Interactions.

Venkata Lokesh Battula, Ph.D., Maria da Graca Cabreira, Ph.D., Zhiqiang Wang, Ph.D., Wencai Ma, Ph.D., Juliana Benito, Ph.D., Peter P. Ruvolo, PhD, Richard Eric Davis, Marina Konopleva, MD, PhD, Michael Andreeff, M.D., Ph.D.

Blood (2010) 116 (21): 3845.

https://doi.org/10.1182/blood.V116.21.3845.3845

Published: 2010

NARROW

The Novel Human Double Minute (HDM)-2 Inhibitor DS-5272 Is Active Both Alone, and In Combination With Other Novel Agents, Against Multiple Myeloma

Bruton′s Tyrosine Kinase Inhibitor Ibrutinib Interferes With Constitutive and Induced Pre-B Cell Receptor Signaling In B-Cell Acute Lymphoblastic Leukemia

The PI3K Delta Inhibitor Idelalisib Interferes With Pre-B Cell Receptor Signaling In Acute Lymphoblastic Leukemia (ALL): A New Therapeutic Concept

Expression Of Truncated Protein Tyrosine Phosphatase, Receptor Type, O (PTPROt) Influences Multiple Myeloma Sensitivity To Bortezomib Through Akt Signaling, and Is a Favorable Clinical Prognostic Factor

CX-5461, a Novel RNA Polymerase I Inhibitor, Is Active Against Wild-Type and Mutant p53 Myeloma Models

Pre-BCR Signaling Activity Predicts Sensitivity To Syk Kinase Inhibition In B Cell Acute Lymphoblastic Leukemia (B-ALL)

Unique Effects of p53 −/− Leukemic Cells On Mesenchymal Stromal Cell Gene Expression Profile in Vitro

NF-κB Activation in Mesenchymal Stromal Cells Mediates Leukemia Cell Chemoresistance

Activation of T and NK Cells Following Lenalidomide Therapy in Patients with Follicular Lymphoma.

Prognostic Impact and Targeting of CRM1 in Acute Myeloid Leukemia

PD-1 + T Cell Subsets in Follicular Lymphoma Tumor Microenvironment and Their Implications for Prognosis and Therapy

Connective Tissue Growth Factor (CTGF) Is Essential for Self Renewal and Proliferation of Mesenchymal Stromal Cells (MSCs) and Affects Leukemia-Stromal Interactions.

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American Society of Hematology

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American Society of Hematology

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