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Journal Articles

Combined Loss of Tet1 and Tet2 Promotes B-Cell, but Not Myeloid Malignancies in Mice

Zhigang Zhao, MDPhD, Lin Li, PhD, Meelad Dawlaty, PhD, Feng Pan, PhD, Zhe Li, PhD, Yuan Zhou, PhD, Hui Shi, MD PhD, Shi Chen, MD PhD, Ophelia Weeks, PhD, Weiping Yuan, PhD, Hongyu Ni, PhD, Feng-Chun Yang, MD PhD, Rudolph Jaenisch, PhD, Peng Jin, MDPhD, Mingjiang Xu, MDPhD

Blood (2015) 126 (23): 3650.

https://doi.org/10.1182/blood.V126.23.3650.3650

Published: 2015

Journal Articles

Developmental Stage and Sex-Specific Role of IGF/IGF1R Signaling in Hematopoietic Stem and Progenitor Cells

Ying Xie, PhD, Xin Hu, PhD, Zhe Li, PhD

Blood (2015) 126 (23): 1157.

https://doi.org/10.1182/blood.V126.23.1157.1157

Published: 2015

Journal Articles

Histone Demethylase LSD1-Mediated Repression of GATA-2 Is Critical for Erythroid Differentiation

Yidi Guo, Yue Li, Tianrui Huang, Dongxue Liang, Zhe Li, PhD, Xin Hu, PhD

Blood (2014) 124 (21): 5128.

https://doi.org/10.1182/blood.V124.21.5128.5128

Published: 2014

Journal Articles

Reduced Erg Dosage Perturbs Fetal and Adult Hematopoiesis

Mia Lee Koch, Xin Zhang, Melanie Hamblen, Frank Godinho, Dirk Reinhardt, MD, Jan-Henning Klusmann, MD, Stuart H. Orkin, MD, Zhe Li, PhD

Blood (2012) 120 (21): 1189.

https://doi.org/10.1182/blood.V120.21.1189.1189

Published: 2012

Journal Articles

the miR-99∼125 P olycistrons Promote Leukemogenesis in a Cell-Context Dependent Manner by Shifting the Balance Between TGFβ- and Wnt-Signaling

Stephan Emmrich, Mareike Rasche, Jennifer Schöning, Zhe Li, PhD, Axel Schambach, MD PhD, Dirk Reinhardt, MD, Jan-Henning Klusmann, MD

Blood (2012) 120 (21): 109.

https://doi.org/10.1182/blood.V120.21.109.109

Published: 2012

Journal Articles

Deciphering the Role of Mir-99∼125 clusters in the Hematopoietic System

Stephan Emmrich, Kerstin Henke, Zhe Li, PhD, Jennifer Schöning, Axel Schambach, MD PhD, Dirk Reinhardt, MD, PhD, Jan-Henning Klusmann, MD

Blood (2011) 118 (21): 213.

https://doi.org/10.1182/blood.V118.21.213.213

Published: 2011

Journal Articles

mTOR Pathway Links Suppressed Autophagy to HDAC Inhibitor-Induced Apoptosis in Myeloid Leukemia,

Metodi V. Stankov, PhD, Kirsten Heitmann, Zhe Li, PhD, Basant Kumar Thakur, PhD, Diana Panayotova-Dimitrova, PhD, Jennifer Schöning, Jean-Pierre Bourquin, MD, PhD, Tino Dittrich, Stephan Emmrich, Nora Schweitzer, MD, Martin Leverkus, MD, Dirk Reinhardt, MD, PhD, Stuart H. Orkin, MD, Georg M.N. Behrens, MD, Jan-Henning Klusmann, MD

Blood (2011) 118 (21): 3614.

https://doi.org/10.1182/blood.V118.21.3614.3614

Published: 2011

Journal Articles

Calpain Drives Megakaryopoiesis by Targeting the 7SK snRNP Complex: A Connection to Down Syndrome Megakaryocytic Neoplasia

Kamaleldin Elagib, PhD, Jeremy D. Rubinstein, Lorrie L. Delehanty, Peter A. Greer, PhD, Shuran Li, Jae K. Lee, PhD, Ivailo S. Mihaylov, PhD, Zhe Li, PhD, Stuart H. Orkin, MD, Adam Goldfarb, MD

Blood (2011) 118 (21): 552.

https://doi.org/10.1182/blood.V118.21.552.552

Published: 2011

Journal Articles

Gene Expression-Based Chemical Genomics Identifies Valproic Acid to Revert the Oncogenic Effect of GATA1s In Down Syndrome Megakaryoblastic Leukemia.

Kirsten Heitmann, Zhe Li, PhD, Jan-Henning Klusmann, MD, Basant Kumar Thakur, PhD, Jennifer Schöning, Jean-Pierre Bourquin, MD, PhD, Stuart H. Orkin, MD, Dirk Reinhardt, MD, PhD

Blood (2010) 116 (21): 3646.

https://doi.org/10.1182/blood.V116.21.3646.3646

Published: 2010

Journal Articles

Developmental Stage-Specific Interplay Between GATA1 and IGF Signaling in Fetal Hematopoiesis and Leukemogenesis.

Jan-Henning Klusmann, MD, Frank Godinho, Kirsten Heitmann, Aliaksandra Maroz, Dirk Reinhardt, MD, PhD, Stuart H Orkin, MD, Zhe Li, PhD

Blood (2009) 114 (22): 386.

https://doi.org/10.1182/blood.V114.22.386.386

Published: 2009

Journal Articles

A Myeloproliferative Disorder in the Tc1 Mouse Model of Down Syndrome

Kate A. Alford, PhD, Lesley Vanes, Zhe Li, PhD, Stuart H. Orkin, MD, Elizabeth M. C. Fisher, PhD, Victor L. J. Tybulewicz, PhD

Blood (2008) 112 (11): 2790.

https://doi.org/10.1182/blood.V112.11.2790.2790

Published: 2008

Journal Articles

GATA1s Mutant Protein Contributes to “Down” Syndrome Megakaryoblastic Leukemia by Derepression of E2F Targets.

Jan-Henning Klusmann, MD, Frank Godinho, Thanaseelan Pushpanathan, Dirk Reinhardt, MD, PhD, Stuart H Orkin, MD, Zhe Li, PhD

Blood (2008) 112 (11): 2248.

https://doi.org/10.1182/blood.V112.11.2248.2248

Published: 2008

Journal Articles

Chromosome 21-Encoded miR-125b and Its Role in the Development of Myeloid Leukemia in Children with Down’s Syndrome.

Jan-Henning Klusmann, MD, Katarina Janikova, Zhe Li, PhD, Stuart H. Orkin, MD, Dirk Reinhardt, MD PhD

Blood (2007) 110 (11): 716.

https://doi.org/10.1182/blood.V110.11.716.716

Published: 2007

Journal Articles

A Genome-Wide Retroviral Insertional Mutagenesis Screen for Genes Cooperating with Truncated, Oncogenic GATA1s.

Zhe Li, PhD, Jan-Henning Klusmann, Frank J. Godinho, BS, Hee-Won Lee, Dirk Reinhardt, MD, Stuart H. Orkin, MD

Blood (2005) 106 (11): 2990.

https://doi.org/10.1182/blood.V106.11.2990.2990

Published: 2005

Journal Articles

A Hypomorphic Cbfb Allele Reveals a Critical Dosage-Sensitive Function of Core Binding Factors at the Earliest Stages of T Cell Development.

Ivan Maillard, MD, PhD, Laleh Talebian, PhD, Zhe Li, PhD, Yalin Guo, MD, Daisuke Sugiyama, MD-PhD, Maren E. Speck, BA, Warren S. Pear, MD-PhD, Nancy A. Speck, PhD

Blood (2005) 106 (11): 124.

https://doi.org/10.1182/blood.V106.11.124.124

Published: 2005

Journal Articles

Developmental Stage-Selective Effect of Somatically Mutated GATA-1 in Down Syndrome AML M7--a Potential Basis for Transient Myeloproliferative Disorder.

Zhe Li, PhD, Frank Godinho, BS, Mireia Garriga-Canut, PhD, Channing Yu, PhD, Stuart H. Orkin, MD

Blood (2004) 104 (11): 463.

https://doi.org/10.1182/blood.V104.11.463.463

Published: 2004

Journal Articles

Loss of Runx1 Perturbs Adult Hematopoiesis and Is Associated with a Myeloproliferative Phenotype.

Joseph D. Growney, PhD, Hirokazu Shigematsu, PhD, Zhe Li, PhD, Benjamin H. Lee, MD, Jennifer Adelsperger, Rebecca Rowan, David P. Curley, Koichi Akashi, MD PhD, Ifor R. Williams, MD PhD, Nancy A. Speck, PhD, D. Gary Gilliland, MD PhD

Blood (2004) 104 (11): 227.

https://doi.org/10.1182/blood.V104.11.227.227

Published: 2004

NARROW

Combined Loss of Tet1 and Tet2 Promotes B-Cell, but Not Myeloid Malignancies in Mice

Developmental Stage and Sex-Specific Role of IGF/IGF1R Signaling in Hematopoietic Stem and Progenitor Cells

Histone Demethylase LSD1-Mediated Repression of GATA-2 Is Critical for Erythroid Differentiation

Reduced Erg Dosage Perturbs Fetal and Adult Hematopoiesis

the miR-99∼125 P olycistrons Promote Leukemogenesis in a Cell-Context Dependent Manner by Shifting the Balance Between TGFβ- and Wnt-Signaling

Deciphering the Role of Mir-99∼125 clusters in the Hematopoietic System

mTOR Pathway Links Suppressed Autophagy to HDAC Inhibitor-Induced Apoptosis in Myeloid Leukemia,

Calpain Drives Megakaryopoiesis by Targeting the 7SK snRNP Complex: A Connection to Down Syndrome Megakaryocytic Neoplasia

Gene Expression-Based Chemical Genomics Identifies Valproic Acid to Revert the Oncogenic Effect of GATA1s In Down Syndrome Megakaryoblastic Leukemia.

Developmental Stage-Specific Interplay Between GATA1 and IGF Signaling in Fetal Hematopoiesis and Leukemogenesis.

A Myeloproliferative Disorder in the Tc1 Mouse Model of Down Syndrome

GATA1s Mutant Protein Contributes to “Down” Syndrome Megakaryoblastic Leukemia by Derepression of E2F Targets.

Chromosome 21-Encoded miR-125b and Its Role in the Development of Myeloid Leukemia in Children with Down’s Syndrome.

A Genome-Wide Retroviral Insertional Mutagenesis Screen for Genes Cooperating with Truncated, Oncogenic GATA1s.

A Hypomorphic Cbfb Allele Reveals a Critical Dosage-Sensitive Function of Core Binding Factors at the Earliest Stages of T Cell Development.

Developmental Stage-Selective Effect of Somatically Mutated GATA-1 in Down Syndrome AML M7--a Potential Basis for Transient Myeloproliferative Disorder.

Loss of Runx1 Perturbs Adult Hematopoiesis and Is Associated with a Myeloproliferative Phenotype.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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