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Yue-Zhong Wu, MS
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Journal Articles

Targeting Mir-155 via The NEDD8-Activating Enzyme Inhibitor MLN4924: A Novel Therapeutic Approach For Acute Myeloid Leukemia (AML)

Jihane C Khalife, MS, Hanna S Radomska, PhD, Jennifer Saultz, MD, Ramasamy Santhanam, PhD, Xiaomeng Huang, Hongyan Wang, PhD, John P. Curfman, Yue-Zhong Wu, MS, Pia Hoellerbauer, Houda Alachkar, PharmD, PhD, Adrienne M Dorrance, Ph.D, Michael A. Caligiuri, MD, Ramiro Garzon, MD, Jason H. Mendler, MD, PhD, Guido Marcucci, MD
Journal: Blood
Blood (2013) 122 (21): 3804.
https://doi.org/10.1182/blood.V122.21.3804.3804
Published: 2013
Journal Articles

Differential Clinical Impact Of Gene Mutations and Their Combinations In Primary Cytogenetically Normal Acute Myeloid Leukemia (CN-AML)

Dimitrios Papaioannou, MD, Kati Maharry, MAS, Krzysztof Mrózek, MD, PhD, Heiko Becker, MD, Klaus H. Metzeler, MD, Jason H. Mendler, MD, PhD, Susan P. Whitman, PhD, Ann-Kathrin Eisfeld, MD, Sebastian Schwind, MD, Yue-Zhong Wu, MS, Deedra Nicolet, MS, Jonathan E. Kolitz, MD, Maria R. Baer, MD, Bayard L. Powell, MD, Donna Bucci, Michael A. Caligiuri, MD, Andrew J. Carroll, PhD, Stefano Volinia, PhD, Richard M. Stone, MD, Guido Marcucci, MD, Clara D. Bloomfield, MD
Journal: Blood
Blood (2013) 122 (21): 2540.
https://doi.org/10.1182/blood.V122.21.2540.2540
Published: 2013
Journal Articles

The Clinical Role of Micrornas (miRs) in Cytogenetically Normal (CN) Acute Myeloid Leukemia (AML): miR-155 Upregulation Independently Identifies High-Risk Patients (Pts)

Guido Marcucci, MD, Kati Maharry, MAS, Klaus H. Metzeler, MD, Stefano Volinia, PhD, Yue-Zhong Wu, MS, Krzysztof Mrózek, MD, PhD, Deedra Nicolet, MS, Jessica Kohlschimdt, Susan Whitman, PhD, Jason H. Mendler, MD, PhD, Sebastian Schwind, MD, Heiko Becker, MD, Ann-Kathrin Eisfeld, MD, Andrew J. Carroll, PhD, Bayard L. Powell, MD, Jonathan E. Kolitz, MD, Ramiro Garzon, MD, Michael A. Caligiuri, M.D., Richard M. Stone, MD, Clara D Bloomfield
Journal: Blood
Blood (2012) 120 (21): 1387.
https://doi.org/10.1182/blood.V120.21.1387.1387
Published: 2012
Journal Articles

Impact of DNMT3A mutations on Clinical Response to the Hypomethylating Agent Decitabine in Older Patients (pts) with Acute Myeloid Leukemia (AML)

Alison R. Walker, MD, Klaus H. Metzeler, MD, Susan Geyer, PhD, Heiko Becker, MD, Sebastian Schwind, MD, Susan P. Whitman, PhD, John Curfman, Yue-Zhong Wu, MS, Danilo Perrotti, MD, Ph.D, Rebecca B. Klisovic, MD, Ramiro Garzon, MD, William Blum, MD, Guido Marcucci, MD
Journal: Blood
Blood (2011) 118 (21): 944.
https://doi.org/10.1182/blood.V118.21.944.944
Published: 2011
Journal Articles

Cytogenetic, Molecular and Clinical Features Associated with Rare CBFB-MYH11 Fusion Transcripts in Patients (Pts) with Acute Myeloid Leukemia (AML) and inv(16)/t(16;16)

Colin G Edwards, PhD, Kati Maharry, MAS, Krzysztof Mrózek, MD, PhD, Sebastian Schwind, MD, Peter Paschka, MD, Deedra Nicolet, MS, Jessica Kohlschmidt, PhD, Thomas W Prior, PhD, Yue-Zhong Wu, MS, Jonathan E. Kolitz, MD, William Blum, MD, Mark J. Pettenati, PhD, Paola Dal Cin, PhD, Andrew J. Carroll, PhD, Michael A Caligiuri, MD, Richard A. Larson, MD, Guido Marcucci, MD, Clara D. Bloomfield, MD
Journal: Blood
Blood (2011) 118 (21): 2514.
https://doi.org/10.1182/blood.V118.21.2514.2514
Published: 2011
Journal Articles

ASXL1 Mutations Identify a High-Risk Subgroup of Older Patients with Primary Cytogenetically Normal Acute Myeloid Leukemia within the European LeukemiaNet ‘Favorable' Genetic Category

Klaus H. Metzeler, MD, Heiko Becker, MD, Kati Maharry, MAS, Michael D. Radmacher, PhD, Jessica Kohlschmidt, PhD, Krzysztof Mrózek, MD, PhD, Deedra Nicolet, MS, Susan P. Whitman, PhD, Yue-Zhong Wu, MS, Sebastian Schwind, MD, Bayard L. Powell, MD, Thomas H. Carter, MD, PhD, Meir Wetzler, MD, Joseph O. Moore, MD, Jonathan E. Kolitz, MD, Maria R. Baer, MD, Andrew J. Carroll, PhD, Richard A. Larson, MD, Michael A Caligiuri, MD, Guido Marcucci, MD, Clara D. Bloomfield, MD
Journal: Blood
Blood (2011) 118 (21): 417.
https://doi.org/10.1182/blood.V118.21.417.417
Published: 2011
Journal Articles

Prognostic Utility of the European LeukemiaNet (ELN) Genetic-Risk Classification in Adults with De Novo Acute Myeloid Leukemia (AML): A Study of 1,550 Patients (Pts)

Krzysztof Mrózek, MD, PhD, Guido Marcucci, MD, Kati Maharry, MAS, Deedra Nicolet, MS, Heiko Becker, MD, Susan P. Whitman, PhD, Klaus H. Metzeler, MD, Sebastian Schwind, MD, Yue-Zhong Wu, MS, Jessica Kohlschmidt, PhD, Mark J. Pettenati, PhD, Prasad R. K. Koduru, PhD, Nyla A. Heerema, PhD, Annemarie W. Block, PhD, Shivanand R. Patil, PhD, Maria R. Baer, MD, Jonathan E. Kolitz, MD, Joseph O. Moore, MD, Andrew J. Carroll, PhD, Richard A. Larson, MD, Clara D. Bloomfield, MD
Journal: Blood
Blood (2011) 118 (21): 414.
https://doi.org/10.1182/blood.V118.21.414.414
Published: 2011
Journal Articles

MiR-3151 , a Novel MicroRNA Embedded in BAALC , Is Only Weakly Co-Expressed with Its Host Gene and Independently Impacts on the Clinical Outcome of Older Patients (Pts) with De Novo Cytogenetically Normal Acute Myeloid Leukemia (CN-AML)

Ann-Kathrin Eisfeld, MD, Guido Marcucci, MD, Kati Maharry, MAS, Sebastian Schwind, MD, Michael D. Radmacher, PhD, Deedra Nicolet, MS, Heiko Becker, MD, Susan P. Whitman, PhD, Klaus H. Metzeler, MD, Krzysztof Mrózek, MD, PhD, Yue-Zhong Wu, MS, Maria R. Baer, MD, Bayard L. Powell, MD, Thomas H. Carter, MD, PhD, Joseph O. Moore, MD, Jonathan E. Kolitz, MD, Meir Wetzler, MD, Michael A Caligiuri, MD, Richard A. Larson, MD, Stephan M. Tanner, PhD, Albert de la Chapelle, MD, PhD, Clara D. Bloomfield, MD
Journal: Blood
Blood (2011) 118 (21): 1462.
https://doi.org/10.1182/blood.V118.21.1462.1462
Published: 2011
Journal Articles

The Mll PTD and Flt3 ITD Double Knock-In Mouse Develops Acute Leukemia and Recapitulates Phenotypic, Molecular and Epigenetic Characteristics of the Counterpart Human Acute Myeloid Leukemia

Nicholas Zorko, Susan P. Whitman, PhD, Kelsie Bernot, PhD, Myntee T. Ngangana, Ronald Siebenaler, Shujun Liu, Ph.D., Yue-Zhong Wu, MS, Chidimma Kalu, Xiaoli Zhang, PhD, MS, David Jarjoura, PhD, Zhiliang Xie, MD, Kenneth K. Chan, PhD, Adrienne M. Dorrance, PhD, Benjamin H. Lee, MD, PhD, Roger Briesewitz, PhD, Danilo Perrotti, MD, PhD, Guido Marcucci, MD, Michael A. Caligiuri, MD
Journal: Blood
Blood (2010) 116 (21): 150.
https://doi.org/10.1182/blood.V116.21.150.150
Published: 2010
Journal Articles

Sole Trisomy 8 In Patients (pts) with De Novo Acute Myeloid Leukemia (AML) Is Associated with Age-Independent Poor Outcome That Is Modified by Molecular Markers and with Unique Gene- and Microrna (miR)-Signatures: a Cancer and Leukemia Group B (CALGB) Study

Heiko Becker, MD, Kati Maharry, MAS, Michael D. Radmacher, PhD, Dean Margeson, MAS, Krzysztof Mrózek, MD, PhD, Susan P. Whitman, PhD, Yue-Zhong Wu, MS, Klaus H. Metzeler, MD, Sebastian Schwind, MD, Kelsi B. Holland, MS, Jonathan E. Kolitz, MD, Andrew J. Carroll, PhD, Michael A. Caligiuri, MD, Maria R. Baer, MD, Richard A. Larson, MD, Guido Marcucci, MD, Clara D. Bloomfield, MD
Journal: Blood
Blood (2010) 116 (21): 577.
https://doi.org/10.1182/blood.V116.21.577.577
Published: 2010
Journal Articles

Interleukin-15 Is a Proto-Oncogene In Acute Large Granular Lymphocyte Leukemia

Anjali Mishra, Ph.D., Shujun Liu, Ph.D., Gregory H Sams, Douglas P Curphey, Ramasamy Santhanam, PhD, Laura J Rush, DVM, PhD, Deanna Schaefer, DVM, Lauren G Falkenberg, Laura Sullivan, Laura Jaroncyk, Xunchang Zou, MS, Harold Fisk, PhD, Jadwiga Labanowska, MS, Enrico Caserta, PhD, Lai-Chu Wu, MD, PhD, Heiko Becker, MD, Sebastian Schwind, MD, Jason C. Chandler, MD, Yue-Zhong Wu, MS, Nyla A. Heerema, Ph.D., Pierluigi Porcu, MD, Ramiro Garzon, MD, Guido Marcucci, MD, Michael A. Caligiuri, MD
Journal: Blood
Blood (2010) 116 (21): 704.
https://doi.org/10.1182/blood.V116.21.704.704
Published: 2010
Journal Articles

Mutations In the Tet Oncogene Family Member 2 ( TET2 ) Gene Refine the New European LeukemiaNet Risk Classification of Primary, Cytogenetically Normal Acute Myeloid Leukemia (CN-AML) In Adults: A Cancer and Leukemia Group B (CALGB) Study

Klaus H. Metzeler, MD, Kati Maharry, MAS, Michael D. Radmacher, PhD, Krzysztof Mrózek, MD, PhD, Dean Margeson, MAS, Heiko Becker, MD, John Curfman, Kelsi B. Holland, MS, Sebastian Schwind, MD, Susan P. Whitman, PhD, Yue-Zhong Wu, MS, William Blum, MD, Bayard L. Powell, MD, Thomas H. Carter, MD, PhD, Meir Wetzler, MD, Joseph O. Moore, MD, Jonathan E. Kolitz, MD, Maria R. Baer, MD, Andrew J. Carroll, PhD, Richard A. Larson, MD, Michael A. Caligiuri, MD, Guido Marcucci, MD, Clara D. Bloomfield, MD
Journal: Blood
Blood (2010) 116 (21): 98.
https://doi.org/10.1182/blood.V116.21.98.98
Published: 2010
Journal Articles

Aberrant Gene Expression of BAALC and ERG in Older [≥60 Years (y)] De Novo Cytogenetically Normal Acute Myeloid Leukemia (CN-AML): A Cancer and Leukemia Group B (CALGB) Study.

Sebastian Schwind, MD, Guido Marcucci, MD, Kati Maharry, MAS, Krzysztof Mrózek, MD, PhD, Michael D. Radmacher, PhD, Kelsi B. Holland, MS, Heiko Becker, MD, Susan P. Whitman, PhD, Yue-Zhong Wu, MS, Maria R Baer, MD, Bayard L. Powell, MD, Andrew J. Carroll, PhD, Michael A. Caligiuri, MD, Richard A. Larson, MD, Clara D. Bloomfield, MD
Journal: Blood
Blood (2009) 114 (22): 214.
https://doi.org/10.1182/blood.V114.22.214.214
Published: 2009
Journal Articles

Evidence of MicroRNA-29b and Sp1/NFκB-HDAC Regulatory Network for KIT Expression in KIT-Driven Acute Myeloid Leukemia (AML): Biologic and Therapeutic Implications.

Shujun Liu, PhD, Lai Chu Wu, PhD, Jiuxia Pang, BS, Ramasamy Santhanam, PhD, Sebastian Schwind, MD, Yue-Zhong Wu, MS, Christopher Hickey, MS, Jianhua Yu, PhD, Anjali Mishra, PhD, Heiko Becker, MD, Chenglong Li, PhD, Roger Briesewitz, PhD, Robert A. Baiocchi, MD, Kenneth K. Chan, PhD, Michael A. Caligiuri, MD, John C. Byrd, MD, Danilo Perrotti, MD, PhD, Ramiro Garzon, MD, Guido Marcucci, MD
Journal: Blood
Blood (2009) 114 (22): 938.
https://doi.org/10.1182/blood.V114.22.938.938
Published: 2009
Journal Articles

Comparison of Clinical and Biologic Significance of WT1 Mutations in Populations of Older (≥60 years[y]) and Younger (<60 y) Adult Patients (Pts) with Cytogenetically Normal (CN) De Novo Acute Myeloid Leukemia (AML): a Cancer and Leukemia Group B (CALGB) Study.

Heiko Becker, MD, Guido Marcucci, MD, Kati Maharry, MAS, Michael D. Radmacher, PhD, Krzysztof Mrózek, MD, PhD, Susan P. Whitman, PhD, Peter Paschka, MD, Dean Margeson, MAS, Yue-Zhong Wu, MS, Sebastian Schwind, MD, Christian Langer, MD, Maria R. Baer, MD, Andrew J. Carroll, PhD, Michael A. Caligiuri, MD, Jonathan E. Kolitz, MD, Richard A. Larson, MD, Clara D. Bloomfield, MD
Journal: Blood
Blood (2009) 114 (22): 326.
https://doi.org/10.1182/blood.V114.22.326.326
Published: 2009
Journal Articles

MicroRNA-181a Targets TEL/AML1 Expression and Impairs Cell Proliferation in t(12;21) Acute Lymphocytic Leukemia (ALL) Cells.

Christopher Hickey, Sebastian Schwind, MD, Heiko Becker, MD, Houda Alachkar, Ramiro Garzon, MD, Yue-Zhong Wu, MS, Shujun Liu, PhD, Danilo Perrotti, MD, PhD, Guido Marcucci, MD
Journal: Blood
Blood (2009) 114 (22): 766.
https://doi.org/10.1182/blood.V114.22.766.766
Published: 2009