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Yankai Zhang, PhD
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Journal Articles

Validation of a Peripheral Blood-Derived Microglia-like Cell System

Yankai Zhang, PhD, Celeste K. Kanne, BA, Jennifer N. Tran, DO, Michael J. Lacagnina, PhD, Peter M. Grace, PhD, Mark J. Burish, MD PhD, Vivien A. Sheehan, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 12–13.
https://doi.org/10.1182/blood-2020-139888
Published: 2020
Journal Articles

Microglia-like Cells Derived from Hematopoietic Stem and Progenitor Cells Are a Model System to Investigate Chronic Pain in Sickle Cell Disease

Yankai Zhang, PhD, Celeste K. Kanne, BA, Jennifer N. Tran, DO, Michael J. Lacagnina, PhD, Peter M. Grace, PhD, Vivien A. Sheehan, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3575.
https://doi.org/10.1182/blood-2019-128921
Published: 2019
Journal Articles

Regulation of Fetal Hemoglobin through the Insulin Signaling Pathway

Alireza Paikari, MD, Yankai Zhang, PhD, Alicia Chang, MD, Ankush Goyal, MA, Evadnie Rampersaud, PhD, Jonathan M. Flanagan, PhD, Mitchell J. Weiss, MD, PhD, Vivien A. Sheehan, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 811.
https://doi.org/10.1182/blood-2019-131313
Published: 2019
Journal Articles

Engineered Human Umbilical Cord Derived Erythroid Progenitor Cells (HUDEP2) with Sickle or β-Thalassemia Mutation: An in-Vitro System for Testing Pharmacological Induction of Fetal Hemoglobin

So Hyun Park, BS, Ciaran M Lee, PhD, Yankai Zhang, PhD, Alicia Chang, MD, Vivien A Sheehan, MD PhD, Gang Bao, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3478.
https://doi.org/10.1182/blood-2018-99-114241
Published: 2018
Journal Articles

The Role of Adenosine Monophosphate Activated Protein Kinase Alpha 1 (AMPK) in Gamma-Globin Regulation

Alicia Chang, MD, Yankai Zhang, PhD, Nelda Itzep, MD, Vivien A Sheehan, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 413.
https://doi.org/10.1182/blood-2018-99-117092
Published: 2018
Journal Articles

Highly Efficient Editing of the Beta-Globin Gene in Patient Derived Hematopoietic Stem and Progenitor Cells to Treat Sickle Cell Disease

So Hyun Park, BS, Ciaran M Lee, PhD, Daniel P. Dever, PhD, Timothy H Davis, BS, Joab Camarena, BS, Yankai Zhang, PhD, Matthew Porteus, MD PhD, Vivian A Sheehan, MD PhD, Gang Bao, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2192.
https://doi.org/10.1182/blood-2018-99-117371
Published: 2018
Journal Articles

Microglia-like Cells Derived from Hematopoietic Stem and Progenitor Cells Are a Model System to Investigate Chronic Pain in Sickle Cell Disease

Yankai Zhang, PhD, Samir K. Ballas, MD, Vivien A Sheehan, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1071.
https://doi.org/10.1182/blood-2018-99-116936
Published: 2018
Journal Articles

Insulin-like Growth Factor Binding Protein-3 (IGFBP3) Induces Fetal Hemoglobin in Hematopoietic Stem and Progenitor Cells from Patients with Sickle Cell Anemia

Alireza Paikari, MD, Tian Mi, PhD, Yankai Zhang, PhD, Evadnie Rampersaud, PhD, Guolian Kang, PhD, Gang Wu, PhD, Jane S. Hankins, MD MS, Jeremie H. Estepp, MD, Pavel Sumazin, PhD, Mitchell J. Weiss, MD PhD, Vivien A Sheehan, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 722.
https://doi.org/10.1182/blood-2018-99-115383
Published: 2018
Journal Articles

Piceatannol Induces Fetal Hemoglobin in Erythroid Progenitor Cells from Patients with Sickle Cell Disease

Yankai Zhang, PhD, Alicia Chang, MD, Pavel Sumazin, PhD, Vivien Sheehan, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2221.
https://doi.org/10.1182/blood.V130.Suppl_1.2221.2221
Published: 2017
Journal Articles

Screening Fetal Hemoglobin Inducing Compounds in Human Umbilical Cord Blood-Derived Erythroid Progenitor Cells

Yankai Zhang, PhD, Ryo Kurita, PhD, Yukio Nakamura, MD PhD, Vivien Sheehan, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2222.
https://doi.org/10.1182/blood.V130.Suppl_1.2222.2222
Published: 2017
Journal Articles

Metformin Induction of Fetal Hemoglobin

Yankai Zhang, PhD, Alireza Paikari, MD, Pavel Sumazin, PhD, Alex George, MD, PhD, Bogdan Dinu, MD, Carly Summarell, MS, Mitchell J Weiss, MD PhD, Vivien Sheehan, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 359.
https://doi.org/10.1182/blood.V130.Suppl_1.359.359
Published: 2017
Journal Articles

Metformin Induces FOXO3-Dependent Fetal Hemoglobin Production in Primary Erythroid Cells

Yankai Zhang, PhD, Mitch Weiss, MD PhD, Pavel Sumazin, PhD, Vivien A. Sheehan, MD PhD
Journal: Blood
Blood (2016) 128 (22): 322.
https://doi.org/10.1182/blood.V128.22.322.322
Published: 2016
Journal Articles

Pharmacological Induction of FOXO3 Is a Potential Treatment for Sickle Cell Disease

Yankai Zhang, PhD, Jacy R Crosby, MS, Eric Boerwinkle, PhD, Betty Pace, MD, Vivien A. Sheehan, MD PhD
Journal: Blood
Blood (2015) 126 (23): 282.
https://doi.org/10.1182/blood.V126.23.282.282
Published: 2015