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Yang Liu, PhD
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Journal Articles

Targeting ROR1 Using the Antibody Drug Conjugate Vls-101 in Aggressive Mantle Cell Lymphoma

Vivian Changying Jiang, PhD, Yang Liu, PhD, Joseph McIntosh, BS, Alexa A Jordan, BS, Angela Leeming, Zhihong Chen, Katti A. Jessen, PhD, Brian J. Lannutti, PhD, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 33.
https://doi.org/10.1182/blood-2020-137660
Published: 2020
Journal Articles

Targeting Antibody Checkpoint Fcgriib Using Monoclonal Antibody BI-1206 to Overcome Therapeutic Resistance in Mantle Cell Lymphoma

Alexa A Jordan, BS, Joseph McIntosh, BS, Yang Liu, PhD, Angela Leeming, William Lee, Ingrid Karlsson, PhD, Linda Mårtensson, PhD, Mathilda Kovacek, Ingrid Teige, PhD, Björn Frendéus, PhD, Michael Wang, MD, Changying Changying Jiang, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 35.
https://doi.org/10.1182/blood-2020-140849
Published: 2020
Journal Articles

Overcoming CAR T Resistance with Non-Covalent BTK Inhibitor Loxo-305 in Mantle Cell Lymphoma

Yang Liu, PhD, Vivian Changying Jiang, PhD, Joseph McIntosh, BS, Alexa A Jordan, BS, Yijing Li, MS, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 10.
https://doi.org/10.1182/blood-2020-137645
Published: 2020
Journal Articles

Ibrutinib Plus Rituximab (IR) Followed By Short Course R-Hypercvad/MTX in Patients (age ≤ 65 years) with Previously Untreated Mantle Cell Lymphoma - Phase-II Window-1 Clinical Trial

Michael Wang, MD, Preetesh Jain, MBBS,MDDM,PhD, Yixin Yao, PhD, Yang Liu, PhD, Shuangtao Zhao, PhD, Holly Hill, Omar Moghrabi, Hun Ju Lee, MD, Felipe Samaniego, MD, Jason Westin, MD, Loretta J. Nastoupil, MD, Rashmi Kanagal-Shamanna, MD, Chi Young Ok, MD, Wendy Chen, Onyeka Oriabure, Yuxuan Che, Yijing Li, MS, Lei Feng, MS, Graciela M. Nogueras González, MPH, Guofang Xu, MD, Nicolaus Wagner-Bartak, MD, Selvi Thirumurthi, David Santos, Guilin Tang, MD, Francisco Vega, MDPhD, C. Cameron Yin, MD PhD, Michelle Avellaneda, Maria Badillo, MSN, RN, OCN, CCRP, Christopher Flowers, MDMS, Linghua Wang, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 35–36.
https://doi.org/10.1182/blood-2020-137259
Published: 2020
Journal Articles

Xeno-MCL: Genomic, Transcriptomic and Pathologic Landscape Associated with Disease Progression, Clonal Evolution and Tissue Tropism in Patient-Derived Xenografts of Mantle Cell Lymphoma

Vivian Changying Jiang, PhD, Shaojun Zhang, PhD, Shuangtao Zhao, PhD, Yang Liu, PhD, Joseph McIntosh, BS, Linghua Wang, MDPhDMS, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 20.
https://doi.org/10.1182/blood-2020-140878
Published: 2020
Journal Articles

Combination of Ibrutinib with Rituximab (IR) in Previously Untreated Older Patients with Mantle Cell Lymphoma (MCL) - a Phase II Clinical Trial

Preetesh Jain, MBBS,MDDM,PhD, Yixin Yao, PhD, Shuangtao Zhao, PhD, Yang Liu, PhD, Holly Hill, Yuxuan Che, Yijing Li, MS, Alexa A Jordan, BS, Joseph McIntosh, BS, Hun Ju Lee, MD, Raphael Eric Steiner, MD, Felipe Samaniego, MD, Jason Westin, MD, Loretta J. Nastoupil, MD, Ranjit Nair, Sairah Ahmed, MD, Chi Young Ok, MD, Rashmi Kanagal-Shamanna, MD, Onyeka Oriabure, Guofang Xu, MD, Wendy Chen, Omar Moghrabi, Chloe Marie McClain, Maria Badillo, MSN, RN, OCN, CCRP, Selvi Thirumurthi, David Santos, Cezar Iliescu, MD, C. Cameron Yin, MD PhD, Shaoying Li, MD, Guilin Tang, MD, Francisco Vega, MDPhD, Sattva S. Neelapu, MD, Christopher Flowers, MDMS, Linghua Wang, PhD, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 41–42.
https://doi.org/10.1182/blood-2020-137167
Published: 2020
Journal Articles

AZD4320 Is a Novel and Potent BCL-2/X L Dual Inhibitor in Targeting Aggressive Mantle Cell Lymphoma

Yijing Li, MS, Yang Liu, PhD, Joseph McIntosh, BS, Alexa A Jordan, BS, Angela Leeming, Courtney L Andersen, PhD, Justin Cidado, PhD, Vivian Changying Jiang, PhD, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 44.
https://doi.org/10.1182/blood-2020-140775
Published: 2020
Journal Articles

Oncogenic MALT1 Promotes Cell Survival and Mediates Ibrutinib Resistance and Ibrutinib-Venetoclax Resistance in Mantle Cell Lymphoma

Vivian Changying Jiang, PhD, Junwei Lian, PhD, Shengjian Huang, PhD, Shaojun Zhang, PhD, Yang Liu, PhD, Linghua Wang, MDPhDMS, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 18.
https://doi.org/10.1182/blood-2020-140871
Published: 2020
Journal Articles

Targeting Glutamine Metabolism Overcomes Resistance to Targeted Therapies in Refractory Mantle Cell Lymphoma

Lingzhi Li, Changying Jiang, PhD, Lucy Jayne Navsaria, Yang Liu, PhD, Angela Leeming, Michael Wang, MD, Yixin Yao, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 25–26.
https://doi.org/10.1182/blood-2020-140736
Published: 2020
Journal Articles

Targeting Transcription Checkpoint Using a Novel CDK9 Inhibitor in Mantle Cell Lymphoma

Junwei Lian, PhD, Yu Xue, PhD, Alexa A Jordan, BS, Joseph McIntosh, BS, Yang Liu, PhD, Michael Wang, MD, Jia Zhou, PhD, Vivian Changying Jiang, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 28–29.
https://doi.org/10.1182/blood-2020-140865
Published: 2020
Journal Articles

Interrogation of Dysregulated Pathways Enables Precision Medicine in Mantle Cell Lymphoma

Yang Liu, PhD, Shuangtao Zhao, PhD, Changying Changying Jiang, PhD, Yixin Yao, PhD, Joseph McIntosh, BS, Alexa A Jordan, BS, Yijing Li, MS, Yuxuan Che, Preetesh Jain, MBBS,MDDM,PhD, Linghua Wang, PhD, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 33.
https://doi.org/10.1182/blood-2020-140794
Published: 2020
Journal Articles

Complex Karyotype Is a Significant Predictor for Worst Outcomes in Patients with Mantle Cell Lymphoma (MCL) Treated with BTK Inhibitors - Comprehensive Analysis of 396 Patients

Preetesh Jain, MBBS,MDDM,PhD, Guilin Tang, MD, C. Cameron Yin, MD PhD, Chi Young Ok, MD, Lucy Navsaria, MB BCh BAO, Maria Badillo, MSN, RN, OCN, CCRP, Wendy Chen, Yijing Li, MS, Yuxuan Che, Yang Liu, PhD, Onyeka Oriabure, Graciela M. Nogueras González, MPH, Jason Westin, MD, Loretta J. Nastoupil, MD, Sairah Ahmed, MD, Ranjit Nair, Selvi Thirumurthi, Shaoying Li, MD, Rashmi Kanagal-Shamanna, MD, Francisco Vega, MDPhD, Christopher Flowers, MDMS, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 32–33.
https://doi.org/10.1182/blood-2020-137473
Published: 2020
Journal Articles

Abemaciclib-Based Combinational Therapies to Overcome Therapeutic Resistance in Mantle Cell Lymphoma

Yuxuan Che, Yang Liu, PhD, Lingzhi Li, Holly Hill, Joseph McIntosh, BS, Alexa A Jordan, BS, Dayoung Jung, Yixin Yao, PhD, Vivian Changying Jiang, PhD, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 33–34.
https://doi.org/10.1182/blood-2020-140856
Published: 2020
Journal Articles

Targeting the Synthetic Lethality Interaction of MTAP and PRMT5 to Overcome Drug Resistance and Enhance Anti-Cancer Immunity in Mantle Cell Lymphoma

Yixin Yao, PhD, Lingzhi Li, Yuxuan Che, Joseph McIntosh, BS, Holly Hill, Yang Liu, PhD, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 15.
https://doi.org/10.1182/blood-2020-138553
Published: 2020
Journal Articles

MCL Cells in Tumor Microenvironment Impair T-Cell Metabolic Fitness and Effector Function

Yixin Yao, PhD, Yuxuan Che, Yang Liu, PhD, Lingzhi Li, Alexa A Jordan, BS, Preetesh Jain, MBBS,MDDM,PhD, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 16.
https://doi.org/10.1182/blood-2020-139611
Published: 2020
Journal Articles

Single Cell Transcriptomic Evolution and Resistance Mechanisms of BTK and BCL-2 Inhibition in Mantle Cell Lymphoma

Vivian Changying Jiang, PhD, Shaojun Zhang, PhD, Junwei Lian, PhD, Yuanxin Wang, Rongjia Zhang, Yang Liu, PhD, Joseph McIntosh, BS, Guangchun Han, Ruiping Wang, PhD, David Santos, Maria Badillo, MSN, RN, OCN, CCRP, Angela Leeming, Zhihong Chen, Kimberly Hartig, John Bigcal, Hun Lee, MD, Raphael Eric Steiner, MD, Jorge Enrique Romaguera, MD, Preetesh Jain, MBBS,MDDM,PhD, Krystle Nomie, PhD, Andy Futreal, Linghua Wang, MDPhDMS, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 33–34.
https://doi.org/10.1182/blood-2020-140882
Published: 2020
Journal Articles

Metabolic Profiling Identifies De Novo Nucleotide Synthesis As a Potential Metabolic Vulnerability for Targeted Therapy Against Mantle Cell Lymphoma

Yixin Yao, PhD, Yang Liu, PhD, Hui Guo, PhD, Makhdum Ahmed, MD PhD MPH, Shabnam Bhuiyan, MSc, Krystle Nomie, PhD, Liang Zhang, MD PhD, Michael Wang, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2945.
https://doi.org/10.1182/blood-2018-99-112192
Published: 2018
Journal Articles

Ibrutinib-Resistant Mantle Cell Lymphoma Undergoes Metabolic Reprogramming Towards Oxphos

Krystle Nomie, PhD, Liang Zhang, MD PhD, Yixin Yao, PhD, Yang Liu, PhD, Shaojun Zhang, PhD, Hui Zhang, Hui Guo, PhD, Makhdum Ahmed, MDPhDMPH, Maria Badillo, Linghua Wang, PhD, Michael Wang, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 41.
https://doi.org/10.1182/blood-2018-99-117279
Published: 2018
Journal Articles

Endothelial Cell-Derived Extracellular Vesicles Mitigate Radiation-Induced Hematopoietic Injury

Sadhna O. Piryani, BS, Yiqun Jiao, MD, Angel Y.F. Kam, PhD, Yang Liu, PhD, Tuan Vo-Dinh, PhD, Benny J. Chen, MD, Nelson J. Chao, MD, Phuong L. Doan, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2581.
https://doi.org/10.1182/blood-2018-99-117058
Published: 2018
Journal Articles

Nfe2 Is Dispensable for Early, but Required for Adult Thrombocyte Formation and Function in Zebrafish

Megan S Rost, PhD, Ilya Shestopalov, PhD, Yang Liu, PhD, Andy H Vo, BS, MS, Francesca Barrett, David L Stachura, PhD, Leonard I. Zon, MD, Jordan A. Shavit, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2534.
https://doi.org/10.1182/blood.V128.22.2534.2534
Published: 2016