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Yadong Liu, MD
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Journal Articles

Smoothened Stabilizes and Protects TRAF6 from Proteosomal Degradation: A Novel Non-Canonical Role of Smoothened with Implications in Lymphoma Biology

Changju QU, MDPhD, Amineh Vaghefi, MD, Kranthi Kunkalla, MS, Jennifer R Chapman, MD, Yadong Liu, MD, Marzenna Blonska, PhD, Juan Pablo Alderuccio, MD, Leon Bernal-Mizrachi, MD, Izidore S Lossos, MD, Ralf Landgraf, PhD, Francisco Vega, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 646.
https://doi.org/10.1182/blood.V130.Suppl_1.646.646
Published: 2017
Journal Articles

Smoothened (SMO) Is an Adaptor Protein That Recruits TRAF6 and Phospholipase C Gamma 2 (PLCg2) to Enhance the Activation of NF-Kb Signaling Pathway

Nitin Agarwal, PhD, Chae Hwa Kim, MD, Kranthi Kunkalla, MS, Gloria Yang, Youley Tjendra, MD, Yadong Liu, MD, Changju Qu, MDPhD, Francisco Vega, MD PhD
Journal: Blood
Blood (2015) 126 (23): 3907.
https://doi.org/10.1182/blood.V126.23.3907.3907
Published: 2015
Journal Articles

Transcriptional Regulation Of GLI1 , Potential New Therapeutic Target For Diffuse Large B-Cell Lymphoma

Nitin K Agarwal, PhD, Kranthi Kunkalla, MS, David H Hawke, PhD, Yadong Liu, MD, Changju Qu, MD PhD, Francisco Vega, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2513.
https://doi.org/10.1182/blood.V122.21.2513.2513
Published: 2013
Journal Articles

Smoothened (SMO) Activates NF-Kb Pathway Through Activation of PKCβ/CARMA1 and TRAF6 Stabilization in Diffuse Large B-Cell Lymphoma

Changju Qu, MD PhD, Yadong Liu, MD, Kranthi Kunkalla, MS, Nitin K Agarwal, PhD, Francisco Vega, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 1298.
https://doi.org/10.1182/blood.V120.21.1298.1298
Published: 2012
Journal Articles

GLI1 Directly Regulates the Transcription of AKT Genes in Diffuse Large B-Cell Lymphoma.

Nitin K Agarwal, PhD, Changju Qu, MD PhD, Kranthi Kunkalla, MS, Yadong Liu, MD, Francisco Vega, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2399.
https://doi.org/10.1182/blood.V120.21.2399.2399
Published: 2012
Journal Articles

The t(14;18)(q32;q21) Confers Resistance to Apoptosis-Induced by Smoothened Inhibitors In Diffuse Large B-Cell Lymphoma That Can Be Restored by Functional Inhibition of BCL2

Kranthi Kunkalla, MS, Changju Qu, MD PhD, Yadong Liu, MD, Rajesh Singh, PhD, Francisco Vega, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 2479.
https://doi.org/10.1182/blood.V118.21.2479.2479
Published: 2011
Journal Articles

Smoothened (SMO), a G-Protein-Coupled Receptor (GPCR) Activated by Hedgehog Ligands, Modulates the Activity Levels of PI3K/AKT and NF-Kβ in Diffuse Large B-Cell Lymphoma,

Changju Qu, MD PhD, Yadong Liu, MD, Kranthi Kunkalla, MS, Nitin K Agarwal, PhD, Estelle Bourbon, MS, Lan V Pham, PhD, Richard J. Ford, MD, PhD, Rajesh Singh, PhD, Francisco Vega, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 3483.
https://doi.org/10.1182/blood.V118.21.3483.3483
Published: 2011